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Clinical Trials

NCT07148245 | RECRUITING
300 Participants

Symptoms of Immune Checkpoint Inhibitor Therapy in Cutaneous Melanoma

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2025-10-13
Completion: 2027-06-30
Conditions
Cutaneous Melanoma Cutaneous Melanoma, Stage III Cutaneous Melanoma by AJCC V7 Stage Cutaneous Melanoma, Stage IV
Interventions
PROCEDURE OTHER
No Results Yet
NCT07142551 | NOT_YET_RECRUITING | PHASE2
60 Participants

Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-12-30
Completion: 2030-06-01
Conditions
Metastatic Castration-resistant Prostate Cancer
Interventions
DRUG
No Results Yet
NCT07142291 | RECRUITING | PHASE2
105 Participants

PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALS

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-30
Completion: 2027-11-30
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Interventions
DRUG
No Results Yet
NCT07139990 | RECRUITING | PHASE1
45 Participants

Personalized Radiotherapy for Individualized Treatment Strategies and Monitoring (PRISM)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-10-28
Completion: 2028-09-01
Conditions
Small Cell Lung Cancer Extensive Stage Brain Metastases Solid Tumor, Adult
Interventions
RADIATION
No Results Yet
NCT07137598 | RECRUITING | PHASE2
160 Participants

A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-09
Completion: 2027-07-09
Conditions
Rheumatoid Arthritis
Interventions
DRUG
No Results Yet
NCT07135453 | NOT_YET_RECRUITING | PHASE4
70 Participants

Induction of Cross-protective Antibodies for Serogroup 33 by Pneumococcal Conjugate Vaccines

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-12-31
Completion: 2026-08-31
Conditions
Vaccine Pneumococcal Disease
Interventions
BIOLOGICAL
No Results Yet
NCT07135427 | RECRUITING | PHASE4
30 Participants

Genetic Variation in IgG in Alpha 1 Antitrypsin Deficiency

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-09-03
Completion: 2027-03-31
Conditions
Alpha 1-Antitrypsin COPD Antibody Deficiency
Interventions
BIOLOGICAL
No Results Yet
NCT07130903 | RECRUITING | PHASE2
102 Participants

Amplitude-Modulated Radiofrequency Electromagnetic Fields (AM RF EMF) in Combination With Fruquintinib in Refractory Metastatic Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-09-10
Completion: 2028-04-17
Conditions
Metastatic Colorectal Adenocarcinoma
Interventions
DRUG DEVICE
No Results Yet
NCT07129993 | RECRUITING | PHASE2/PHASE3
630 Participants

Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-09-26
Completion: 2029-06-01
Conditions
Urothelial Cancer Bladder Cancer
Interventions
DRUG
No Results Yet
NCT07121452 | RECRUITING | NA
160 Participants

Telehealth for Sleep Apnea: Effectiveness, Implementation, and Cost in the Military Health System

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-10-15
Completion: 2028-01-31
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
BEHAVIORAL
No Results Yet
NCT07119320 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated: 2025-11-10
No Results Yet
NCT07119268 | RECRUITING | NA
115 Participants

SPARK Healthy Sleep

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-10-24
Completion: 2026-10-01
Conditions
Schizophrenia and Related Disorders Sleep Disturbance
Interventions
DEVICE
No Results Yet
NCT07109817 | NOT_YET_RECRUITING | PHASE2
116 Participants

Desloratadine to Prevent Taxane-induced Peripheral Neuropathy in Patients With Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-30
Completion: 2029-01-31
Conditions
Breast Cancer Peripheral Neuropathy
Interventions
DRUG
No Results Yet
NCT07108283 | RECRUITING | PHASE2
200 Participants

A Study of Zasocitinib in Adults With Nonsegmental Vitiligo

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-03
Completion: 2027-10-12
Conditions
Nonsegmental Vitiligo
Interventions
DRUG OTHER
No Results Yet
NCT07107230 | RECRUITING | PHASE1
380 Participants

A Study of JNJ-95437446 in Participants With Advanced-Stage Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-15
Completion: 2027-11-18
Conditions
Colorectal Neoplasms
Interventions
DRUG
No Results Yet
NCT07104500 | RECRUITING | PHASE3
4500 Participants

VK2735 for Weight Management Phase 3

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-23
Completion: 2027-07-01
Conditions
Weight Loss
Interventions
DRUG
No Results Yet
NCT07104383 | RECRUITING | PHASE3
1100 Participants

VK2735 for Weight Management Type 2 Diabetes Phase 3 (VANQUISH 2)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-23
Completion: 2027-07-01
Conditions
Weight Loss
Interventions
DRUG
No Results Yet
NCT07104279 | RECRUITING
150 Participants

Z1 Hip System: Post-Market Clinical Follow Up Study

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2025-10-13
Completion: 2028-08-31
Conditions
Hip Osteoarthritis Acute Traumatic Fracture of the Femoral Head or Neck Avascular Necrosis of the Femoral Head
Interventions
DEVICE
No Results Yet
NCT07103902 | NOT_YET_RECRUITING | NA
50 Participants

Aerobic Exercise and Obsessive-Compulsive Disorder Symptoms

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-12-01
Completion: 2026-09-01
Conditions
Obsessive-Compulsive Disorder (OCD)
Interventions
BEHAVIORAL
No Results Yet
NCT07096843 | RECRUITING | PHASE2
45 Participants

A Phase 2 Study of Budoprutug in Subjects With Primary Membranous Nephropathy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-08-25
Completion: 2027-10-31
Conditions
Primary Membranous Nephropathy
Interventions
DRUG
No Results Yet
NCT07091864 | RECRUITING | NA
116 Participants

Continuous Glucose Monitoring for the Management of Hyperglycemia in Patients With Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-29
Completion: 2027-11-30
Conditions
Glioblastoma, IDH-Wildtype WHO Grade 4 Glioma
Interventions
OTHER PROCEDURE
No Results Yet
NCT07091422 | RECRUITING | NA
20 Participants

A Split-Mouth Clinical Trial Evaluating the Bond Failure Rate of a New Etch-Free Orthodontic Adhesive

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-05
Completion: 2026-08-11
Conditions
Bracket Bonding Orthodontic Treatment Dental Adhesives/Restorations Performance White Spot Lesion of Tooth
Interventions
DEVICE
No Results Yet
NCT07090226 | RECRUITING | NA
65 Participants

Diffuse Cutaneous Scleroderma (DSSc) SFDI Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-06
Completion: 2028-12-31
Conditions
Systemic Scleroderma Diffuse Cutaneous Scleroderma
Interventions
OTHER
No Results Yet
NCT07089576 | RECRUITING | NA
132 Participants

Clinical Study to Evaluate the Safety and Effectiveness of Arcevo LSA

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-04
Completion: 2028-04-30
Conditions
Aortic Arch Aneurysm Aortic Arch Dissection Chronic Aortic Dissection Acute Aortic Dissection
Interventions
DEVICE
No Results Yet
NCT07082725 | RECRUITING | PHASE3
72 Participants

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-30
Completion: 2027-11-04
Conditions
Niemann-Pick Type C Disease
Interventions
DRUG
No Results Yet
NCT07082543 | RECRUITING | PHASE3
75 Participants

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of GM1 Gangliosidosis or GM2 Gangliosidosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-30
Completion: 2027-11-04
Conditions
Gangliosidoses, GM2 Gangliosidosis, GM1
Interventions
DRUG
No Results Yet
NCT07077746 | RECRUITING | PHASE2
46 Participants

HB-adMSCs for the Treatment of Crohn's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-01-31
Completion: 2027-12-31
Conditions
Crohn Disease (CD)
Interventions
DRUG
No Results Yet
NCT07076186 | NOT_YET_RECRUITING | PHASE2
48 Participants

Phase II Decentralized Pragmatic Trial of Adjuvant Doxorubicin - Trabectedin Chemotherapy in uLMS

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-12-01
Completion: 2027-12-02
Conditions
Uterine Leiomyosarcoma
Interventions
DRUG
No Results Yet
NCT07076160 | COMPLETED | NA
74 Participants

Pilot Dispensing Study of Two Marketed Daily Disposable Multifocal Contact Lenses

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-24
Completion: 2025-09-20
Conditions
Visual Acuity Presbyopia
Interventions
DEVICE
No Results Yet
NCT07075588 | NOT_YET_RECRUITING | NA
100 Participants

Integrating Free-choice Marketplace, dieTitian coacHing, cultuRally Tailored messagIng to improVE Blood Pressure

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-01-01
Completion: 2026-11-30
Conditions
Hypertension Hypertension Complicated With Type 2 Diabetes
Interventions
BEHAVIORAL
No Results Yet
NCT07066722 | RECRUITING | PHASE1
124 Participants

A Study to Evaluate VH4524184 Tablet Absorption, Effects of Food, and Interactions With Other Drugs in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-07
Completion: 2025-12-15
Conditions
HIV Infections
Interventions
DRUG
No Results Yet
NCT07061652 | RECRUITING | NA
162 Participants

Expanding the Support of Family Caregivers of Diverse Patients With Cancer and Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-03
Completion: 2026-06-30
Conditions
Cancer Diabetes
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT07056699 | NOT_YET_RECRUITING | PHASE3
24 Participants

SGLT2i, Pioglitazone, and Ketone Production in T1D

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-01-30
Completion: 2027-06-01
Conditions
Type1diabetes
Interventions
DRUG OTHER
No Results Yet
NCT07056361 | RECRUITING | NA
60 Participants

Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-12-16
Completion: 2026-12-31
Conditions
Movement Disorders (Incl Parkinsonism) Stroke Traumatic Brain Injury Brain Diseases Parkinson Disease Essential Tremor, Movement Disorders
Interventions
DEVICE
No Results Yet
NCT07056348 | RECRUITING | NA
60 Participants

Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-05-10
Completion: 2030-12-31
Conditions
Traumatic Brain Injury Stroke Brain Disease Movement Disorders (Incl Parkinsonism) Central Nervous System Disease Essential Tremor, Movement Disorders Essential Tremor of Voice
Interventions
DEVICE
No Results Yet
NCT07056335 | COMPLETED | NA
108 Participants

Physical Activity and Percussive Massage Therapy for Reducing Pain in Older Women

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-01-15
Completion: 2025-10-14
Conditions
Pain, Chronic
Interventions
BEHAVIORAL DEVICE
No Results Yet
NCT07054515 | RECRUITING | PHASE3
147 Participants

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-30
Completion: 2027-11-04
Conditions
Niemann-Pick Type C Disease GM1 Gangliosidosis GM2 Gangliosidosis
Interventions
DRUG
No Results Yet
NCT07054489 | RECRUITING | NA
10 Participants

UPBEAT: Using Polygenic Scores to Guide BB Therapy in HF With Mildly Reduced EF

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-30
Completion: 2026-11-30
Conditions
Heart Failure Polygenic Score
Interventions
OTHER
No Results Yet
NCT07053345 | RECRUITING | PHASE4
47 Participants

A Study of Esketamine Nasal Spray in Korean Participants With Treatment-resistant Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-09
Completion: 2027-06-25
Conditions
Depressive Disorder, Treatment-Resistant
Interventions
DRUG
No Results Yet
NCT07049926 | RECRUITING | PHASE1/PHASE2
140 Participants

Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-20
Completion: 2031-10-26
Conditions
Renal Cell Carcinoma
Interventions
DRUG
No Results Yet
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