Clinical Trials

NCT06910813 | RECRUITING | PHASE1/PHASE2
30 Participants

DFT383 in Pediatric Participants With Nephropathic Cystinosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-02
Completion: 2031-03-14
Conditions
Nephropathic Cystinosis
Interventions
GENETIC
No Results Yet
NCT06910761 | RECRUITING | PHASE2
35 Participants

Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-05-05
Completion: 2028-10-02
Conditions
Anatomic Stage IV Breast Cancer AJCC v8 Metastatic Breast Carcinoma Metastatic Lung Non-Small Cell Carcinoma Metastatic Malignant Neoplasm in the Leptomeninges Stage IV Lung Cancer AJCC v8
Interventions
PROCEDURE RADIATION OTHER
No Results Yet
NCT06907979 | NOT_YET_RECRUITING | NA
24 Participants

Cannabis and Processing Emotions Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-01-31
Completion: 2027-05-31
Conditions
Cannabis Use Disorder, Severe
Interventions
DEVICE
No Results Yet
NCT06906926 | RECRUITING | NA
80 Participants

Harmony TPV EMEA PMS

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-30
Completion: 2027-07-31
Conditions
Severe Pulmonary Valve Regurgitation
Interventions
RADIATION
No Results Yet
NCT06903897 | RECRUITING | NA
68000 Participants

Social Needs Screening and Chronic Diseases Study (WE CARE)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-10-08
Completion: 2028-09-30
Conditions
Hyperlipidemias Diabetes Depression Pediatric Asthma Hypertension
Interventions
OTHER
No Results Yet
NCT06902480 | NOT_YET_RECRUITING | NA
24 Participants

Dairy Choline Bioavailability

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-30
Completion: 2026-08-31
Conditions
Post-menopausal Women Post-menopausal Status
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT06895681 | NOT_YET_RECRUITING
50000 Participants

UCSF Biobank for Hereditary Cancers and Tumor-Associated Mutations

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2026-01-31
Completion: 2035-12-31
Conditions
Solid Tumor Solid Tumor, Adult Somatic Mutation Solid Tumor, Unspecified, Adult Hereditary Cancer
Interventions
PROCEDURE OTHER
No Results Yet
NCT06883305 | RECRUITING | PHASE3
990 Participants

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-18
Completion: 2029-03-13
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06878404 | RECRUITING | PHASE3
540 Participants

A Study to Evaluate the Efficacy and Safety of JNJ-77242113 (Icotrokinra) in Biologic-naรฏve Participants With Active Psoriatic Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-21
Completion: 2026-05-27
Conditions
Arthritis, Psoriatic
Interventions
DRUG
No Results Yet
NCT06878261 | RECRUITING | PHASE3
990 Participants

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-25
Completion: 2029-03-13
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06878131 | RECRUITING
40 Participants

Precision-MRD: Prospective Observational Study of Biomarker-directed Systemic Therapy for Colorectal Cancer Patients With Minimal Residual Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2025-04-18
Completion: 2026-12-22
Conditions
Colorectal Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT06877676 | APPROVED_FOR_MARKETING

Pre-Approval Expanded Access Study for TAR-200 Treating Physician Use

Study Type: EXPANDED_ACCESS
Last Updated: 2025-11-10
Conditions
Non-Muscle Invasive Bladder Neoplasms
Interventions
DRUG
No Results Yet
NCT06876259 | NOT_YET_RECRUITING | NA
300 Participants

Artificial Intelligence Diagnostic Decision Support to Reduce Antimicrobial Prescriptions in Young Children With Colds

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-30
Completion: 2026-11-30
Conditions
Acute Otitis Media (AOM) Upper Respiratory Infection
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06871579 | RECRUITING | NA
25 Participants

Study of the Esophageal String Test (EST) for the Diagnosis of Helicobacter Pylori

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-11
Completion: 2026-01-30
Conditions
Helicobacter Pylori
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06870812 | RECRUITING | NA
600 Participants

Rapid Evacuation and Access of Cerebral Hemorrhage Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-05-27
Completion: 2030-03-31
Conditions
Stroke Hemorrhagic
Interventions
PROCEDURE OTHER
No Results Yet
NCT06866288 | COMPLETED | NA
32 Participants

Belongingness in Nursing Through Mindfulness - BEING Mindful: A Pilot Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-04-29
Completion: 2025-10-14
Conditions
Mindfulness Sense of Belonging
Interventions
BEHAVIORAL
No Results Yet
NCT06866106 | RECRUITING | NA
50 Participants

Well-being in IBS: Strengths and Happiness (WISH) 2.0

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-10-30
Completion: 2028-04-30
Conditions
Irritable Bowel Syndrome
Interventions
BEHAVIORAL
No Results Yet
NCT06864858 | COMPLETED | NA
53 Participants

Clinical Evaluation of Two Cosmetic Contact Lenses

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-30
Completion: 2025-05-05
Conditions
Visual Acuity
Interventions
DEVICE
No Results Yet
NCT06863961 | RECRUITING | PHASE2
160 Participants

A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-04-01
Completion: 2026-07-13
Conditions
Atopic Dermatitis
Interventions
DRUG
No Results Yet
NCT06863129 | RECRUITING | NA
334 Participants

Proximal FEmur Reconstruction or Internal Fixation fOR Metastases (PERFORM) Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-01
Completion: 2029-06-01
Conditions
Metastatic Bone Disease
Interventions
PROCEDURE
No Results Yet
NCT06860594 | RECRUITING | PHASE1
30 Participants

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-30
Completion: 2027-06-30
Conditions
Astrocytoma, IDH-Mutant, Grade 2 Recurrent Adult Diffuse Hemispheric Glioma, H3 G34-Mutant Recurrent Adult Diffuse Midline Glioma, H3 K27-Mutant Recurrent Astrocytoma, IDH-Mutant Recurrent Astrocytoma, IDH-Mutant, Grade 3 Recurrent Astrocytoma, IDH-Mutant, Grade 4 Recurrent Glioblastoma, IDH-Wildtype
Interventions
PROCEDURE RADIATION DRUG
No Results Yet
NCT06858813 | RECRUITING | PHASE1
232 Participants

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-04-14
Completion: 2030-09-30
Conditions
Hepatocellular Cancer Squamous-Cell Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT06855498 | RECRUITING | PHASE3
600 Participants

Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-28
Completion: 2028-02-28
Conditions
Hidradenitis Suppurativa (HS)
Interventions
DRUG
No Results Yet
NCT06852222 | RECRUITING | PHASE3
600 Participants

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-04
Completion: 2029-06-22
Conditions
Leukemia, Myeloid, Acute
Interventions
DRUG
No Results Yet
NCT06850922 | RECRUITING | PHASE1/PHASE2
546 Participants

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RO7446603 Administered Alone or in Combination With Aflibercept or Faricimab in Participants With Diabetic Macular Edema

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-06-22
Completion: 2027-04-30
Conditions
Diabetic Macular Edema
Interventions
DRUG
No Results Yet
NCT06843239 | RECRUITING | PHASE2
80 Participants

Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-06
Completion: 2026-12-31
Conditions
Systemic Sclerosis (SSc) Scleroderma
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06841354 | RECRUITING | PHASE3
1000 Participants

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-16
Completion: 2030-05-18
Conditions
Triple Negative Breast Neoplasms
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06834347 | RECRUITING | PHASE3
210 Participants

A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-12
Completion: 2027-01-08
Conditions
Chronic Rhinosinusitis With Nasal Polyps
Interventions
DRUG
No Results Yet
NCT06833294 | RECRUITING
48 Participants

GentleFit Non-Invasive Ventilation (NIV) Interface Trial

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2025-10-24
Completion: 2026-10-30
Conditions
Device Ineffective Device Induced Injury
Interventions
DEVICE
No Results Yet
NCT06832618 | RECRUITING | PHASE3
240 Participants

A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-17
Completion: 2026-07-13
Conditions
Atopic Dermatitis
Interventions
DRUG
No Results Yet
NCT06824181 | RECRUITING | PHASE3
580 Participants

Study of Mixed Vaccination Schedules With a 21-valent Pneumococcal Conjugate Vaccine and a 20-valent Pneumococcal Conjugate Vaccine in Healthy Infants From Approximately 2 Months of Age

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-27
Completion: 2027-08-26
Conditions
Pneumococcal Immunization
Interventions
BIOLOGICAL
No Results Yet
NCT06822426 | RECRUITING | PHASE3
200 Participants

Comparing The Safety And Efficacy Of DEFENCATHยฎ In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-05-14
Completion: 2027-01-31
Conditions
Central Line Associated Blood Stream Infections (CLABSI)
Interventions
DRUG
No Results Yet
NCT06822374 | WITHDRAWN | PHASE2/PHASE3
0 Participants

Hypertonic Saline in Posterior Spinal Fusion

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-12-31
Completion: 2028-05-31
Conditions
Scoliosis Idiopathic Scoliosis;Congenital
Interventions
DRUG
No Results Yet
NCT06821997 | RECRUITING | PHASE2
20 Participants

NALIRIFOX Before Surgery for the Treatment of Borderline Resectable Pancreatic Ductal Adenocarcinoma, Nectar Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-12-01
Completion: 2027-03-01
Conditions
Borderline Resectable Pancreatic Ductal Adenocarcinoma
Interventions
PROCEDURE DRUG
No Results Yet
NCT06817382 | RECRUITING | PHASE1
12 Participants

A Study to Investigate the Safety and Biodistribution of a Single Intrathecal (IT) Injection of INS1201 in Ambulatory Males With Duchenne Muscular Dystrophy (DMD)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-22
Completion: 2028-01-31
Conditions
Duchenne Muscular Dystrophy
Interventions
GENETIC
No Results Yet
NCT06813014 | NOT_YET_RECRUITING | PHASE4
400 Participants

Pharmacogenetics of Response to Sitagliptin (PRS)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-01-31
Completion: 2031-12-31
Conditions
Diabetes
Interventions
PROCEDURE
No Results Yet
NCT06810505 | RECRUITING | PHASE3
420 Participants

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-02-13
Completion: 2031-03-31
Conditions
Chronic Migraine
Interventions
DRUG
No Results Yet
NCT06809595 | RECRUITING | PHASE3
250 Participants

A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-01-29
Completion: 2026-11-30
Conditions
Generalized Anxiety Disorder
Interventions
OTHER DRUG
No Results Yet
NCT06808984 | RECRUITING | PHASE2
120 Participants

Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-09
Completion: 2027-07-27
Conditions
Agitation Alzheimer Disease
Interventions
DRUG
No Results Yet
NCT06807463 | RECRUITING | PHASE2
48 Participants

A Trial to Assess the Efficacy and Safety of TEV-53408 in Adults With Celiac Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-31
Completion: 2026-09-15
Conditions
Celiac Disease
Interventions
DRUG
No Results Yet
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