Clinical Trials
Showing trials with last updates posted in 2025.
990
Participants
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-03-18
Completion:
2029-03-13
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
BIOLOGICAL
OTHER
No Results Yet
540
Participants
A Study to Evaluate the Efficacy and Safety of JNJ-77242113 (Icotrokinra) in Biologic-naïve Participants With Active Psoriatic Arthritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-02-21
Completion:
2026-05-27
Conditions
Arthritis, Psoriatic
Interventions
DRUG
No Results Yet
990
Participants
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-03-25
Completion:
2029-03-13
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
BIOLOGICAL
OTHER
No Results Yet
40
Participants
Precision-MRD: Prospective Observational Study of Biomarker-directed Systemic Therapy for Colorectal Cancer Patients With Minimal Residual Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2025-04-18
Completion:
2026-12-22
Conditions
Colorectal Cancer
Interventions
BEHAVIORAL
No Results Yet
Pre-Approval Expanded Access Study for TAR-200 Treating Physician Use
Study Type:
EXPANDED_ACCESS
Last Updated:
2025-11-10
Conditions
Non-Muscle Invasive Bladder Neoplasms
Interventions
DRUG
No Results Yet
300
Participants
Artificial Intelligence Diagnostic Decision Support to Reduce Antimicrobial Prescriptions in Young Children With Colds
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-11-30
Completion:
2026-11-30
Conditions
Acute Otitis Media (AOM)
Upper Respiratory Infection
Interventions
DIAGNOSTIC_TEST
No Results Yet
25
Participants
Study of the Esophageal String Test (EST) for the Diagnosis of Helicobacter Pylori
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-06-11
Completion:
2026-01-30
Conditions
Helicobacter Pylori
Interventions
DIAGNOSTIC_TEST
No Results Yet
600
Participants
Rapid Evacuation and Access of Cerebral Hemorrhage Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-05-27
Completion:
2030-03-31
Conditions
Stroke Hemorrhagic
Interventions
PROCEDURE
OTHER
No Results Yet
32
Participants
Belongingness in Nursing Through Mindfulness - BEING Mindful: A Pilot Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-04-29
Completion:
2025-10-14
Conditions
Mindfulness
Sense of Belonging
Interventions
BEHAVIORAL
No Results Yet
50
Participants
Well-being in IBS: Strengths and Happiness (WISH) 2.0
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-10-30
Completion:
2028-04-30
Conditions
Irritable Bowel Syndrome
Interventions
BEHAVIORAL
No Results Yet
53
Participants
Clinical Evaluation of Two Cosmetic Contact Lenses
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-03-30
Completion:
2025-05-05
Conditions
Visual Acuity
Interventions
DEVICE
No Results Yet
160
Participants
A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-04-01
Completion:
2026-07-13
Conditions
Atopic Dermatitis
Interventions
DRUG
No Results Yet
334
Participants
Proximal FEmur Reconstruction or Internal Fixation fOR Metastases (PERFORM) Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-02-01
Completion:
2029-06-01
Conditions
Metastatic Bone Disease
Interventions
PROCEDURE
No Results Yet
30
Participants
Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-07-30
Completion:
2027-06-30
Conditions
Astrocytoma, IDH-Mutant, Grade 2
Recurrent Adult Diffuse Hemispheric Glioma, H3 G34-Mutant
Recurrent Adult Diffuse Midline Glioma, H3 K27-Mutant
Recurrent Astrocytoma, IDH-Mutant
Recurrent Astrocytoma, IDH-Mutant, Grade 3
Recurrent Astrocytoma, IDH-Mutant, Grade 4
Recurrent Glioblastoma, IDH-Wildtype
Interventions
PROCEDURE
RADIATION
DRUG
No Results Yet
232
Participants
A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-04-14
Completion:
2030-09-30
Conditions
Hepatocellular Cancer
Squamous-Cell Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
600
Participants
Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-02-28
Completion:
2028-02-28
Conditions
Hidradenitis Suppurativa (HS)
Interventions
DRUG
No Results Yet
600
Participants
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-06-04
Completion:
2029-06-22
Conditions
Leukemia, Myeloid, Acute
Interventions
DRUG
No Results Yet
546
Participants
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RO7446603 Administered Alone or in Combination With Aflibercept or Faricimab in Participants With Diabetic Macular Edema
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2022-06-22
Completion:
2027-04-30
Conditions
Diabetic Macular Edema
Interventions
DRUG
No Results Yet
80
Participants
Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-02-06
Completion:
2026-12-31
Conditions
Systemic Sclerosis (SSc)
Scleroderma
Interventions
BIOLOGICAL
OTHER
No Results Yet
1000
Participants
A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-03-16
Completion:
2030-05-18
Conditions
Triple Negative Breast Neoplasms
Interventions
BIOLOGICAL
DRUG
No Results Yet
210
Participants
A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-02-12
Completion:
2027-01-08
Conditions
Chronic Rhinosinusitis With Nasal Polyps
Interventions
DRUG
No Results Yet
48
Participants
GentleFit Non-Invasive Ventilation (NIV) Interface Trial
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2025-10-24
Completion:
2026-10-30
Conditions
Device Ineffective
Device Induced Injury
Interventions
DEVICE
No Results Yet
240
Participants
A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-06-17
Completion:
2026-07-13
Conditions
Atopic Dermatitis
Interventions
DRUG
No Results Yet
580
Participants
Study of Mixed Vaccination Schedules With a 21-valent Pneumococcal Conjugate Vaccine and a 20-valent Pneumococcal Conjugate Vaccine in Healthy Infants From Approximately 2 Months of Age
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-02-27
Completion:
2027-08-26
Conditions
Pneumococcal Immunization
Interventions
BIOLOGICAL
No Results Yet
200
Participants
Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-05-14
Completion:
2027-01-31
Conditions
Central Line Associated Blood Stream Infections (CLABSI)
Interventions
DRUG
No Results Yet
0
Participants
Hypertonic Saline in Posterior Spinal Fusion
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-12-31
Completion:
2028-05-31
Conditions
Scoliosis Idiopathic
Scoliosis;Congenital
Interventions
DRUG
No Results Yet
20
Participants
NALIRIFOX Before Surgery for the Treatment of Borderline Resectable Pancreatic Ductal Adenocarcinoma, Nectar Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-12-01
Completion:
2027-03-01
Conditions
Borderline Resectable Pancreatic Ductal Adenocarcinoma
Interventions
PROCEDURE
DRUG
No Results Yet
12
Participants
A Study to Investigate the Safety and Biodistribution of a Single Intrathecal (IT) Injection of INS1201 in Ambulatory Males With Duchenne Muscular Dystrophy (DMD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-07-22
Completion:
2028-01-31
Conditions
Duchenne Muscular Dystrophy
Interventions
GENETIC
No Results Yet
400
Participants
Pharmacogenetics of Response to Sitagliptin (PRS)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2026-01-31
Completion:
2031-12-31
Conditions
Diabetes
Interventions
PROCEDURE
No Results Yet
420
Participants
A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-02-13
Completion:
2031-03-31
Conditions
Chronic Migraine
Interventions
DRUG
No Results Yet
250
Participants
A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-01-29
Completion:
2026-11-30
Conditions
Generalized Anxiety Disorder
Interventions
OTHER
DRUG
No Results Yet
120
Participants
Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-06-09
Completion:
2027-07-27
Conditions
Agitation
Alzheimer Disease
Interventions
DRUG
No Results Yet
48
Participants
A Trial to Assess the Efficacy and Safety of TEV-53408 in Adults With Celiac Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-03-31
Completion:
2026-09-15
Conditions
Celiac Disease
Interventions
DRUG
No Results Yet
750
Participants
A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced Participants With Active Psoriatic Arthritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-01-09
Completion:
2027-02-10
Conditions
Arthritis, Psoriatic
Interventions
DRUG
No Results Yet
45
Participants
Inaxaplin in Participants With Proteinuric APOL1 Mediated Kidney Disease With or Without Comorbidities
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-02-04
Completion:
2026-12-30
Conditions
Proteinuric Kidney Disease
Interventions
DRUG
No Results Yet
120
Participants
A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-03-12
Completion:
2027-05-31
Conditions
Metastatic Colorectal Cancer
Interventions
DRUG
No Results Yet
414
Participants
A Phase I Study of SIM0505 in Participants With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-02-26
Completion:
2028-02-29
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
450
Participants
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-04-09
Completion:
2032-05-30
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
650
Participants
FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-01-28
Completion:
2028-04-30
Conditions
Metastatic Head and Neck Squamous Cell Carcinoma
Recurrent Head and Neck Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
40120
Participants
The Effects of Orexin Antagonism on Fear Extinction in PTSD
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2026-01-01
Completion:
2032-03-01
Conditions
Insomnia
PTSD
Interventions
DRUG
No Results Yet
Showing 40 trials per page · Total 107903 trials