Clinical Trials

NCT06663332 | RECRUITING | PHASE3

196 Participants

A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-10-29

Completion: 2031-12-12

Conditions

Crohns Disease Colitis, Ulcerative Arthritis, Psoriatic Arthritis, Juvenile

Interventions

DRUG

No Results Yet

NCT06663319 | RECRUITING | PHASE1

170 Participants

A Study of JNJ-89402638 for Metastatic Colorectal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-10-15

Completion: 2028-02-25

Conditions

Unresectable Metastatic Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT06662786 | RECRUITING | PHASE3

1000 Participants

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-10-18

Completion: 2028-12-15

Conditions

Colorectal Neoplasms

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT06662162 | RECRUITING | NA

100 Participants

Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-05-07

Completion: 2027-03-31

Conditions

Age-Related Macular Degeneration Age-related Macular Degeneration (ARMD) Intermediate AMD Geographic Atrophy Secondary to Age-related Macular Degeneration

Interventions

DEVICE

No Results Yet

NCT06660563 | ACTIVE_NOT_RECRUITING | PHASE1

19 Participants

A Study of JNJ-80948543 in Combination With Other CD3 T-Cell Engagers in Participants With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (R/R B-Cell NHL)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-10-22

Completion: 2026-09-21

Conditions

Lymphoma, Non-Hodgkin

Interventions

DRUG

No Results Yet

NCT06657144 | RECRUITING | PHASE1

154 Participants

A Study of CHS-114 in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-04-01

Completion: 2027-05-31

Conditions

Metastatic Solid Tumor Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT06655740 | ACTIVE_NOT_RECRUITING | NA

16 Participants

Safety, Tolerability, and Effectiveness of Duodenal Mucosal RF Vapor Ablation for Insulin Elimination in Type-2 Diabetes

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-10-01

Completion: 2027-06-30

Conditions

Diabetes Mellitus, Type 2

Interventions

DEVICE

No Results Yet

NCT06651528 | NOT_YET_RECRUITING | NA

264 Participants

Trauma-informed Intervention to Reduce Substance Use and to Support Community Transition

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-12-31

Completion: 2029-09-30

Conditions

Substance Use Disorder (SUD)

Interventions

BEHAVIORAL OTHER

No Results Yet

NCT06646289 | RECRUITING | PHASE2

42 Participants

A Follow-on Study for Second-Eye Treatment for Participants Previously Treated With Gene Therapy for X-Linked Retinitis Pigmentosa (XLRP)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-10-10

Completion: 2030-10-24

Conditions

X-Linked Retinitis Pigmentosa

Interventions

BIOLOGICAL OTHER

No Results Yet

NCT06635889 | RECRUITING | PHASE2

116 Participants

Intravesical Bupivacaine on Post-Operative Ureteroscopy Pain

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-03-26

Completion: 2029-10-31

Conditions

Nephrolithiasis

Interventions

DRUG OTHER

No Results Yet

NCT06635785 | RECRUITING | PHASE1/PHASE2

204 Participants

Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-03-26

Completion: 2026-06-30

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT06635148 | RECRUITING | PHASE2

311 Participants

A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-09-19

Completion: 2029-08-24

Conditions

Geographic Atrophy Macular Degeneration

Interventions

DRUG OTHER

No Results Yet

NCT06635135 | TERMINATED | PHASE3

48 Participants

A Study of Aticaprant Plus an Antidepressant to Prevent Return of Depression Symptoms in Participants With Major Depressive Disorder Who Experience a Loss of Interest and Pleasure

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-09-19

Completion: 2025-04-09

Conditions

Depressive Disorder, Major Anhedonia

Interventions

DRUG OTHER

No Results Yet

NCT06634589 | RECRUITING | PHASE1/PHASE2

80 Participants

A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-11-27

Completion: 2028-12-02

Conditions

B-cell Malignancy Relapsed Cancer Refractory Cancer B-cell Lymphoma

Interventions

DRUG

No Results Yet

NCT06631638 | RECRUITING | NA

118 Participants

EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-10-30

Completion: 2027-12-31

Conditions

Osteoarthritis Traumatic Arthritis Rheumatoid Arthritis Congential Hip Dysplasia Avascular Necrosis of the Femoral Head Certain Cases of Ankylosis

Interventions

DEVICE

No Results Yet

NCT06630429 | ACTIVE_NOT_RECRUITING

100 Participants

A Pilot Study of Blood-based Biomarkers for Response to Immune Checkpoint Inhibitors

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2020-09-02

Completion: 2026-07-31

Conditions

Non-Small Cell Lung Cancer Renal Cell Carcinoma (RCC)

Interventions

OTHER

No Results Yet

NCT06628934 | ACTIVE_NOT_RECRUITING

600 Participants

Wearable Gait Sensors

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2017-06-23

Completion: 2025-12-31

Conditions

Spinocerebellar Ataxia

No Results Yet

NCT06625775 | RECRUITING | PHASE1

392 Participants

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-10-29

Completion: 2028-11-30

Conditions

Solid Tumor, Adult Metastatic Breast Cancer Advanced Breast Cancer HER2 Mutation-Related Tumors HER2-positive Metastatic Breast Cancer KRAS Mutant Metastatic Colorectal Cancer Metastatic Lung Cancer Metastatic Colorectal Cancer Advanced Lung Cancer HR-positive, HER2-negative Advanced Breast Cancer HER2-positive Advanced Breast Cancer

Interventions

DRUG

No Results Yet

NCT06625177 | RECRUITING | PHASE1

36 Participants

A Trial to Test the Safety and Efficacy of TEV-53408 in Treating Vitiligo

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-11-11

Completion: 2026-05-09

Conditions

Vitiligo

Interventions

DRUG

No Results Yet

NCT06624228 | ACTIVE_NOT_RECRUITING | PHASE3

684 Participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Study Participants With Active Psoriatic Arthritis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-10-21

Completion: 2026-02-03

Conditions

Psoriatic Arthritis

Interventions

DRUG

No Results Yet

NCT06624085 | RECRUITING | PHASE1

50 Participants

A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-04-28

Completion: 2030-03-31

Conditions

Lymphoma

Interventions

DRUG

No Results Yet

NCT06620042 | COMPLETED | PHASE2

20 Participants

FMRI of Patients Receiving IV Ketamine for Treatment Resistant Bipolar Depression

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-11-12

Completion: 2025-10-31

Conditions

Bipolar Depression Treatment Resistant Bipolar Depression

Interventions

DRUG OTHER

No Results Yet

NCT06618534 | RECRUITING | PHASE2

1120 Participants

Azithromycin for Meningococcal Carriage

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-11-12

Completion: 2026-05-31

Conditions

Meningococcal Infections

Interventions

DRUG

No Results Yet

NCT06615050 | RECRUITING | PHASE3

572 Participants

A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-04-02

Completion: 2031-01-17

Conditions

Graft-versus-host Disease (GVHD)

Interventions

DRUG

No Results Yet

NCT06614309 | RECRUITING | NA

45 Participants

Non-invasive Treatment for Long COVID (Post COVID-19 Condition) Brain Fog

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-09-24

Completion: 2026-04-30

Conditions

Long COVID

Interventions

OTHER

No Results Yet

NCT06613568 | RECRUITING | NA

50 Participants

Moda-flx Hemodialysis System™ Under Professional Care Settings by Trained Individuals and At Home by Participants

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-10-06

Completion: 2027-03-31

Conditions

End Stage Kidney Disease

Interventions

DEVICE

No Results Yet

NCT06608485 | RECRUITING

165 Participants

A Study of HARMONIC 700 Shears With Advanced Hemostasis in Pediatric and Adult Surgical Procedures

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2025-01-23

Completion: 2026-05-15

Conditions

Pediatric Surgical Procedures Adult Surgical Procedures Adult Gynecological Procedures Adult Urological Procedures Adult Thoracic Procedures

Interventions

DEVICE

No Results Yet

NCT06608212 | ACTIVE_NOT_RECRUITING

150000 Participants

An Observational Study to Learn More About How Safe Finerenone is and How Well it Works in People With Chronic Kidney Disease and Type 2 Diabetes in Routine Medical Care in the United States

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2024-10-09

Completion: 2025-12-31

Conditions

Chronic Kidney Disease Type 2 Diabetes Mellitus

Interventions

DRUG

No Results Yet

NCT06607458 | RECRUITING | PHASE2

90 Participants

Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-08-05

Completion: 2026-12-31

Conditions

Refractory Metastatic Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT06596577 | ENROLLING_BY_INVITATION | PHASE3

18000 Participants

Nudging Effective and Equitable Delivery of Specialty Palliative Care

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-08-06

Completion: 2028-03-01

Conditions

Serious Illness Palliative

Interventions

BEHAVIORAL

No Results Yet

NCT06595953 | RECRUITING | PHASE2

150 Participants

Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-12-04

Completion: 2029-10-01

Conditions

Psychiatric Disorders Anxiety Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT06593483 | COMPLETED | NA

120 Participants

Increasing Effectiveness of an Alcohol Use Reduction Exercise Using Self-Talk Videos

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-04-15

Completion: 2024-11-26

Conditions

Heavy Drinking

Interventions

BEHAVIORAL

No Results Yet

NCT06589115 | WITHDRAWN | NA

0 Participants

Blood Flow Restriction Therapy Improves Tibial Plateau Fracture Recovery

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-12-01

Completion: 2027-12-01

Conditions

Tibial Plateau Fractures

Interventions

OTHER

No Results Yet

NCT06588738 | ACTIVE_NOT_RECRUITING | PHASE3

840 Participants

A Study in Patients With Moderate to Severe Plaque Psoriasis to Evaluate the Efficacy and Safety of ESK-001

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-08-20

Completion: 2025-09-23

Conditions

Plaque Psoriasis

Interventions

DRUG

No Results Yet

NCT06588634 | RECRUITING | NA

200 Participants

The PERSEVERE Study

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-12-16

Completion: 2026-12-31

Conditions

Pulmonary Embolism Pulmonary Thromboembolism

Interventions

DEVICE PROCEDURE

No Results Yet

NCT06586112 | ACTIVE_NOT_RECRUITING | PHASE3

840 Participants

A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Moderate to Severe Plaque Psoriasis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-07-25

Completion: 2025-09-19

Conditions

Plaque Psoriasis

Interventions

DRUG

No Results Yet

NCT06585774 | RECRUITING | PHASE3

240 Participants

A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2025-01-21

Completion: 2027-09-28

Conditions

Chronic Graft-versus-host-disease

Interventions

DRUG

No Results Yet

NCT06581406 | RECRUITING | PHASE2/PHASE3

280 Participants

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-12-17

Completion: 2030-01-31

Conditions

Metastatic Uveal Melanoma

Interventions

BIOLOGICAL

No Results Yet

NCT06579794 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated: 2025-11-10

No Results Yet

NCT06577025 | ACTIVE_NOT_RECRUITING | PHASE2

43 Participants

A Study of Different Sequences of Cilta-cel, Talquetamab in Combination With Daratumumab and Teclistamab in Combination With Daratumumab Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in Participants With Standard-risk Newly Diagnosed Multiple Myeloma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-08-20

Completion: 2030-07-31

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet