A Study of HARMONIC 700 Shears With Advanced Hemostasis in Pediatric and Adult Surgical Procedures

NCT ID: NCT06608485

Last Updated: 2025-11-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

165 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-01-23

Study Completion Date

2026-08-15

Brief Summary

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The main purpose of this study is to demonstrate acceptable performance and assess safety of the HARMONIC 700 Shears device in a post-market setting when used per the instructions for use in pediatric and adult surgical procedures.

Detailed Description

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Conditions

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Pediatric Surgical Procedures Adult Surgical Procedures Adult Gynecological Procedures Adult Urological Procedures Adult Thoracic Procedures

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Pediatric; Adult Surgical Procedures (HARMONIC 700 Shears)

This prospective study will involve collection of clinical data in a post-market setting from pediatric surgical procedures (general) and adult surgical procedures (general, gynecological, urological, and thoracic surgical procedures). Investigators will perform each procedure using the device in compliance with their standard surgical approach and the HARMONIC 700 Shears instruction for use (IFU). All subjects enrolled will be followed post-operatively through discharge and again at approximately 28 days post-surgery.

HARMONIC 700 Shears

Intervention Type DEVICE

There is no intervention, beyond necessary clinical care, in this study. HARMONIC 700 Shears for vessel transection were used according to instructions for use.

Interventions

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HARMONIC 700 Shears

There is no intervention, beyond necessary clinical care, in this study. HARMONIC 700 Shears for vessel transection were used according to instructions for use.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

Pediatric participants

* Non-emergent procedure (general) where at least one vessel is planned to be transected by the HARMONIC 700 Shears per the IFU
* Less than 18 years of age at the time of procedure
* Participant's parent/legal guardian must give permission to participate in the study and provide written informed consent for the participant Adult participants
* Elective procedure (general, gynecological, urological, or thoracic) where at least one vessel is planned to be transected by the HARMONIC 700 Shears per the IFU
* Elective procedure (general, gynecological, urological, or thoracic) where at least one vessel is planned to be transected by the HARMONIC 700 Shears per the IFU

Exclusion Criteria

Preoperative

* Physical or psychological condition which would impair study participation
* Participants of childbearing potential who are pregnant
* Enrollment in a concurrent interventional clinical study that could impact the study endpoints Intraoperative
* HARMONIC 700 Shears were not attempted to be used for at least one single vessel transection during the surgical procedure
Maximum Eligible Age

110 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ethicon Endo-Surgery

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ethicon Endo-Surgery, Inc. Clinical Trial

Role: STUDY_DIRECTOR

Ethicon Endo-Surgery, Inc.

Locations

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Riley Hospital for Children at Indiana University Health

Indianapolis, Indiana, United States

Site Status RECRUITING

NextStage Clinical Research

Wichita, Kansas, United States

Site Status WITHDRAWN

Icahn School of Medicine at Mt. Sinai

New York, New York, United States

Site Status RECRUITING

The Methodist Hospital Research Institute D B A Houston Methodist Research Institute

Houston, Texas, United States

Site Status WITHDRAWN

Centre Hospitalier de l'Universite de Montreal

Montreal, Quebec, Canada

Site Status RECRUITING

Dorset County Hospital Nhs Foundation Trust

Dorchester, , United Kingdom

Site Status COMPLETED

Western General Hospital

Edinburgh, , United Kingdom

Site Status RECRUITING

Southampton General Hospital

Southampton, , United Kingdom

Site Status RECRUITING

Countries

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United States Canada United Kingdom

Central Contacts

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Study Contact

Role: CONTACT

Phone: 904-443-1474

Email: [email protected]

Other Identifiers

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ENG202301

Identifier Type: OTHER

Identifier Source: secondary_id

ENG202301

Identifier Type: -

Identifier Source: org_study_id