Clinical Trials

NCT05838742 | TERMINATED | PHASE2

314 Participants

A Dose-Finding Study to Evaluate the Efficacy and Safety of GSK3858279 in Adults With Knee Osteoarthritis (OA) Pain

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-09-13

Completion: 2024-08-12

Conditions

Pain Osteoarthritis, Knee

Interventions

DRUG

Results Available

NCT05828589 | RECRUITING | PHASE1

112 Participants

A Study of BGB-21447, a Bcl-2 Inhibitor, in Mature B-Cell Malignancies

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-06-20

Completion: 2027-04-30

Conditions

Relapsed Non-Hodgkin Lymphoma Refractory Non-Hodgkin Lymphoma Relapsed Chronic Lymphocytic Leukemia Refractory Chronic Lymphocytic Leukemia Relapsed Follicular Lymphoma Relapsed Marginal Zone Lymphoma Relapse Diffuse Large B Cell Lymphoma Relapsed Small Lymphocytic Lymphoma Refractory Follicular Lymphoma Refractory Marginal Zone Lymphoma Refractory Small Lymphocytic Lymphoma Richter Transformation Refractory Diffuse Large B-cell Lymphoma Transformed Non-Hodgkin Lymphoma

Interventions

DRUG

No Results Yet

NCT05818683 | RECRUITING | PHASE1

185 Participants

A Study of JNJ-78278343 in Combination With Either JNJ-63723283 (Cetrelimab), Taxane Chemotherapy, or Androgen Receptor Pathway Inhibitors for Metastatic Prostate Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-04-26

Completion: 2026-06-30

Conditions

Metastatic Castration-resistant Prostate Neoplasms Metastatic Hormone-sensitive Prostate Cancer

Interventions

DRUG

No Results Yet

NCT05818540 | COMPLETED | NA

173 Participants

Sleep Apnea Study in Adults Using DreamPort-Eclipse and a Traditional Nasal Mask

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-04-17

Completion: 2023-12-29

Conditions

Obstructive Sleep Apnea

Interventions

DEVICE

Results Available

NCT05811351 | ACTIVE_NOT_RECRUITING | PHASE2

305 Participants

A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-03-06

Completion: 2026-02-26

Conditions

Geographic Atrophy

Interventions

DRUG OTHER

No Results Yet

NCT05807139 | RECRUITING | PHASE1

20 Participants

Spironolactone in Alcohol Use Disorder (SAUD)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-07-13

Completion: 2025-12-31

Conditions

Alcohol Use Disorder

Interventions

OTHER DRUG

No Results Yet

NCT05802615 | COMPLETED | NA

60 Participants

Protective Assets Reinforced With Integrated Care and TechnologY (PARITY) Feasibility Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-04-06

Completion: 2025-08-06

Conditions

Maternal Health Blood Pressure

Interventions

BEHAVIORAL OTHER

No Results Yet

NCT05800405 | RECRUITING | EARLY_PHASE1

9 Participants

Evaluation of Bridging Radiation Therapy Before CAR T-Cell Infusion for the Treatment of Relapsed or Refractory Large B-Cell Lymphoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-07-20

Completion: 2026-01-13

Conditions

Recurrent Diffuse Large B-Cell Lymphoma Refractory Diffuse Large B-Cell Lymphoma

Interventions

PROCEDURE BIOLOGICAL RADIATION

No Results Yet

NCT05799105 | RECRUITING | PHASE4

122 Participants

OPEN Versus InTact Capsule Proton Pump Inhibitors for the Treatment of Marginal Ulcers

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-03-14

Completion: 2025-12-23

Conditions

Marginal Ulcer

Interventions

DRUG

No Results Yet

NCT05798117 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

21 Participants

An Open-label, Study to Assess Safety, Efficacy and Cellular Kinetics of YTB323 in Severe, Refractory Systemic Lupus Erythematosus

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-02-28

Completion: 2026-09-09

Conditions

Systemic Lupus Erythematosus Lupus Nephritis

Interventions

DRUG

No Results Yet

NCT05797168 | RECRUITING | PHASE1/PHASE2

506 Participants

Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-06-05

Completion: 2028-01-06

Conditions

Ovarian Cancer Lung Adenocarcinoma Endometrial Cancer

Interventions

DRUG

No Results Yet

NCT05796375 | RECRUITING | NA

240 Participants

Replacing Invasive Cystoscopy With Urine Testing for Non-muscle Invasive Bladder Cancer Surveillance

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-11-17

Completion: 2028-11-30

Conditions

Non-muscle-invasive Bladder Cancer

Interventions

PROCEDURE DIAGNOSTIC_TEST

No Results Yet

NCT05794997 | COMPLETED

817337 Participants

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Propranolol/Carvedilol Versus Atenolol/Bisoprolol/Sotalol

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2022-11-30

Completion: 2023-01-01

Conditions

Hypertension

Interventions

DRUG

Results Available

NCT05789082 | RECRUITING | PHASE1/PHASE2

240 Participants

A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-06-20

Completion: 2032-01-29

Conditions

Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05784441 | RECRUITING | PHASE1

20 Participants

A Study of JNJ-90009530 in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (r/r B-NHL)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-11-06

Completion: 2037-10-30

Conditions

Relapsed or Refractory B Cell Non-Hodgkin Lymphoma

Interventions

DRUG

No Results Yet

NCT05776030 | RECRUITING | NA

30 Participants

Multi-speed Ergonomic Wheelchair

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-07-18

Completion: 2026-02-27

Conditions

Spinal Cord Diseases Spinal Cord Injuries

Interventions

DEVICE

No Results Yet

NCT05773040 | RECRUITING | PHASE1

33 Participants

A Phase 1 Study of JV-213 Autologous CD79b-targeting Chimeric Antigen Receptor T-cell Therapy in Adults With Relapsed or Refractory B-cell Lymphomas

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-04-14

Completion: 2025-12-31

Conditions

Lymphomas B-cell Lymphomas

Interventions

DRUG PROCEDURE

No Results Yet

NCT05768945 | COMPLETED

742670 Participants

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Semaglutide v DPP4 Inhibitors

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2022-11-30

Completion: 2023-07-07

Conditions

Diabetes

Interventions

DRUG

Results Available

NCT05766852 | COMPLETED | NA

31 Participants

Potential Benefits of the Somatic Psychoeducational Intervention

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-10-23

Completion: 2024-04-11

Conditions

Work Related Stress

Interventions

BEHAVIORAL

No Results Yet

NCT05764135 | COMPLETED | NA

33 Participants

SCI-Lynx: A Mobile Platform for Physical Activity Social Support for People With SCI Pilot Study

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-06-14

Completion: 2024-10-01

Conditions

Spinal Cord Injuries

Interventions

BEHAVIORAL

No Results Yet

NCT05761951 | ACTIVE_NOT_RECRUITING | PHASE2

8 Participants

Phase 2 Study Evaluating the Efficacy of the Combination of DKN-01 (DKK1 Inhibitor, Leap Therapeutics) and Pembrolizumab in the Treatment of Advanced or Recurrent Endometrial Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-08-29

Completion: 2027-01-31

Conditions

Endometrial Cancer

Interventions

DRUG

No Results Yet

NCT05757869 | ACTIVE_NOT_RECRUITING | PHASE3

20296 Participants

A Study of Milvexian Versus Apixaban in Participants With Atrial Fibrillation

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-04-11

Completion: 2026-10-31

Conditions

Atrial Fibrillation

Interventions

DRUG

No Results Yet

NCT05754957 | RECRUITING | PHASE3

16000 Participants

A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-04-07

Completion: 2026-09-07

Conditions

Acute Coronary Syndrome

Interventions

DRUG OTHER

No Results Yet

NCT05742802 | RECRUITING | PHASE3

1869 Participants

Long-term Efficacy and Safety of Tozorakimab in Participants With Chronic Obstructive Pulmonary Disease With a History of Exacerbations (PROSPERO).

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-03-06

Completion: 2026-06-16

Conditions

Chronic Obstructive Pulmonary Disease (COPD)

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05739981 | RECRUITING | PHASE1/PHASE2

50 Participants

Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2023-02-10

Completion: 2026-08-30

Conditions

Ovarian Cancer Fallopian Tube Cancer Primary Peritoneal Cancer

Interventions

DRUG

No Results Yet

NCT05731544 | COMPLETED | PHASE1/PHASE2

443 Participants

Study of BMF-219 in Healthy Adult Subjects and in Adult Subjects With Type 2 Diabetes Mellitus (T2D)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-08-17

Completion: 2024-11-18

Conditions

Type 2 Diabetes Mellitus

Interventions

DRUG

No Results Yet

NCT05724121 | RECRUITING

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-11-30

Completion: 2024-11-20

Conditions

Atrial Fibrillation With Rapid Ventricular Response Hypotension Drug-Induced

Interventions

DRUG OTHER

Results Available