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Clinical Trials

NCT05076617 | ENROLLING_BY_INVITATION | PHASE3
300 Participants

A Study to Test the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-02-03
Completion: 2028-11-30
Conditions
Stereotypical Prolonged Seizures
Interventions
DRUG
No Results Yet
NCT05074264 | ACTIVE_NOT_RECRUITING | NA
1586 Participants

Screening Algorithms for Cervical and Anal High-Grade Squamous Intraepithelial Lesions in People With HIV in Mexico and Puerto Rico

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-11-30
Completion: 2027-12-31
Conditions
AIDS-Related Anal Carcinoma AIDS-Related Cervical Carcinoma High Grade Anal Intraepithelial Neoplasia High Grade Cervical Intraepithelial Neoplasia HIV Infection
Interventions
PROCEDURE
No Results Yet
NCT05072483 | RECRUITING
155 Participants

Natural History Study of CADASIL

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2022-04-18
Completion: 2034-06-01
Conditions
Cardiovascular Disease Arterial Stiffness Germline Mutation in the NOTCH 3 Gene Pathogenesis of CADASIL Clinical Phenotype of CADASIL
Interventions
DEVICE
No Results Yet
NCT05063162 | RECRUITING | PHASE3
104 Participants

A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOG-AD)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-02-02
Completion: 2027-05-06
Conditions
Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOG-AD)
Interventions
DRUG OTHER
No Results Yet
NCT05061238 | RECRUITING | NA
15 Participants

Impact Of Muscle Vibration On Gait Control

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-10-04
Completion: 2025-12-31
Conditions
Muscle
Interventions
DEVICE
No Results Yet
NCT05060016 | ACTIVE_NOT_RECRUITING | PHASE2
222 Participants

A Phase 2 Study of Tarlatamab in Patients With Small Cell Lung Cancer (SCLC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-12-01
Completion: 2026-04-30
Conditions
Relapsed/Refractory Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT05059236 | ACTIVE_NOT_RECRUITING | PHASE2
223 Participants

A Study to Learn How Well Darolutamide Administered Together With Androgen Deprivation Therapy (ADT) Works in Men With Metastatic Hormone-sensitive Prostate Cancer. Results Will be Compared With ADT Alone From a Previously Conducted Study.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-11-04
Completion: 2025-05-30
Conditions
Metastatic Hormone-sensitive Prostate Cancer
Interventions
DRUG OTHER
No Results Yet
NCT05054413 | RECRUITING
10 Participants

Formulating Expert Consensus Guidelines in Cancer Care Using the Delphi Method

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2021-04-15
Completion: 2026-05-01
Conditions
Hematopoietic and Lymphoid Cell Neoplasm Malignant Solid Neoplasm
Interventions
OTHER
No Results Yet
NCT05053152 | RECRUITING | PHASE2
194 Participants

Testing the Addition of the Drug Relugolix to the Usual Radiation Therapy for Advanced-Stage Prostate Cancer, The NRG Promethean Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-04-20
Completion: 2029-02-01
Conditions
Oligometastatic Prostate Carcinoma Prostate Adenocarcinoma Prostate Ductal Adenocarcinoma Prostate Intraductal Carcinoma Stage IVB Prostate Cancer AJCC v8
Interventions
PROCEDURE OTHER DRUG RADIATION
No Results Yet
NCT05050162 | SUSPENDED | PHASE2/PHASE3
1714 Participants

Comparing Cisplatin Every Three Weeks to Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-02-01
Completion: 2026-02-09
Conditions
Advanced Head and Neck Squamous Cell Carcinoma Advanced Hypopharyngeal Squamous Cell Carcinoma Advanced Laryngeal Squamous Cell Carcinoma Advanced Oropharyngeal Squamous Cell Carcinoma Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 Stage III Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8 Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8 Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Interventions
DRUG PROCEDURE OTHER RADIATION
No Results Yet
NCT05050097 | ACTIVE_NOT_RECRUITING | PHASE1
166 Participants

A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-09-22
Completion: 2025-03-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05050084 | RECRUITING | PHASE3
2050 Participants

Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-12-06
Completion: 2026-11-11
Conditions
Prostate Adenocarcinoma
Interventions
DRUG RADIATION
No Results Yet
NCT05049798 | ACTIVE_NOT_RECRUITING
1314 Participants

A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2021-08-25
Completion: 2027-08-01
Conditions
Arthritis, Psoriatic
Interventions
DRUG
No Results Yet
NCT05049616 | COMPLETED | PHASE4
70 Participants

Oral Combined Hydrochlorothiazide/Lisinopril Versus Oral Nifedipine for Postpartum Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-10-18
Completion: 2022-06-26
Conditions
Hypertension in Pregnancy Postpartum Preeclampsia
Interventions
DRUG
Results Available
NCT05040386 | COMPLETED | NA
50 Participants

Nurse Coach-Led Early Palliative Care for Older Adults With COPD and Their Care Partners: The Project EPIC Pilot RCT

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-05-19
Completion: 2024-10-25
Conditions
COPD
Interventions
BEHAVIORAL OTHER
Results Available
NCT05039619 | RECRUITING | PHASE2
40 Participants

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-05-12
Completion: 2027-08-31
Conditions
Lupus Nephritis
Interventions
DRUG
No Results Yet
NCT05023993 | ACTIVE_NOT_RECRUITING | NA
20 Participants

The Effect of Exercise and Nicotinamide Riboside Muscle Health and Insulin Resistance in Survivors of Childhood Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-06-23
Completion: 2026-09-21
Conditions
Hematopoietic and Lymphoid Cell Neoplasm Malignant Solid Neoplasm Prediabetes
Interventions
OTHER DIETARY_SUPPLEMENT
No Results Yet
NCT05023967 | ACTIVE_NOT_RECRUITING | PHASE2
37 Participants

Metformin and Nightly Fasting in Women With Early Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-04-04
Completion: 2025-12-16
Conditions
Anatomic Stage I Breast Cancer AJCC v8 Anatomic Stage II Breast Cancer AJCC v8 Breast Ductal Carcinoma In Situ Invasive Breast Carcinoma
Interventions
PROCEDURE DRUG OTHER
No Results Yet
NCT05022849 | ACTIVE_NOT_RECRUITING | PHASE1
15 Participants

A Study of JNJ-75229414 for Metastatic Castration-resistant Prostate Cancer Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-09-28
Completion: 2037-10-30
Conditions
Prostatic Neoplasms
Interventions
DRUG
No Results Yet
NCT05020444 | RECRUITING | PHASE1
18 Participants

TriPRIL CAR T Cells in Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-10-05
Completion: 2026-01-01
Conditions
Multiple Myeloma Multiple Myeloma in Relapse Refractory Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05015439 | RECRUITING | PHASE1
40 Participants

Cannabidiol (CBD) in Adults With ASD

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-04-20
Completion: 2026-12-31
Conditions
Autism Spectrum Disorder
Interventions
DRUG
No Results Yet
NCT05012124 | ACTIVE_NOT_RECRUITING | NA
297 Participants

Using Technology to Optimize Collaborative Care Management of Depression in Urban and Rural Cancer Centers, SCOPE

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-04-15
Completion: 2025-10-28
Conditions
Depression Hematopoietic and Lymphoid Cell Neoplasm Malignant Solid Neoplasm
Interventions
OTHER
No Results Yet
NCT05011045 | RECRUITING
100 Participants

Neurocognitive Outcomes After Whole Brain Radiation Therapy for Hematologic Malignancies

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2020-01-09
Completion: 2026-10-31
Conditions
Central Nervous System Lymphoma Hematopoietic and Lymphoid Cell Neoplasm Leukemia Lymphoma Plasma Cell Myeloma Secondary Central Nervous System Lymphoma
Interventions
PROCEDURE OTHER
No Results Yet
NCT05006716 | RECRUITING | PHASE1/PHASE2
614 Participants

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-09-13
Completion: 2026-11-30
Conditions
B-cell Malignancy Marginal Zone Lymphoma Follicular Lymphoma Non-Hodgkin Lymphoma Waldenström Macroglobulinemia Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma Mantle Cell Lymphoma Diffuse Large B Cell Lymphoma
Interventions
DRUG
No Results Yet
NCT05001828 | ACTIVE_NOT_RECRUITING | PHASE1
38 Participants

Study of ADI-PEG 20, Venetoclax and Azacitidine in Acute Myeloid Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-04-05
Completion: 2025-12-31
Conditions
Acute Myeloid Leukemia, Adult
Interventions
DRUG
No Results Yet
NCT04998006 | COMPLETED
77 Participants

Alcohol and Cannabis Co-Use and the Gut-Brain Axis

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2022-02-25
Completion: 2024-12-23
Conditions
Cannabis Use Alcohol Use Inflammation
No Results Yet
NCT04995081 | COMPLETED | PHASE2
60 Participants

Clinical Trial for Parkinson's Disease Using Allogeneic HB-adMSCs (Early and Moderate PD)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-07-16
Completion: 2025-10-03
Conditions
Parkinson Disease
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT04982653 | RECRUITING | PHASE2
140 Participants

Short Stitch Versus Traditional Suture for the Prevention of Incisional Hernia After Open Hepatectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-01-04
Completion: 2026-04-30
Conditions
Liver and Intrahepatic Bile Duct Neoplasm Metastatic Malignant Neoplasm in the Liver Primary Malignant Liver Neoplasm
Interventions
OTHER PROCEDURE
No Results Yet
NCT04964739 | COMPLETED | NA
224 Participants

Gender/Sex & CUD Remission

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-11-15
Completion: 2025-10-27
Conditions
Cannabis Use Disorder, Mild Cannabis Use Disorder, Moderate Cannabis Use Disorder, Severe
Interventions
BEHAVIORAL
No Results Yet
NCT04955626 | COMPLETED | PHASE3
16372 Participants

To Evaluate the Safety, Tolerability, Efficacy and Immunogenicity of BNT162b2 Boosting Strategies Against COVID-19 in Participants ≥12 Years of Age.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-07-01
Completion: 2023-05-25
Conditions
SARS-CoV-2 Infection COVID-19
Interventions
BIOLOGICAL OTHER
Results Available
NCT04937166 | TERMINATED | PHASE1
25 Participants

A Study of Dual-SIgnaling Protein 107 (DSP107) for Patients With Hematological Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-01-13
Completion: 2025-04-23
Conditions
Acute Myeloid Leukemia Myelodysplastic Syndromes Chronic Myelomonocytic Leukemia
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT04931797 | ACTIVE_NOT_RECRUITING | NA
900 Participants

Video Images About Decisions for Ethical Outcomes in the Emergency Department (VIDEO-ED)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-04-25
Completion: 2025-06-10
Conditions
Emergencies
Interventions
BEHAVIORAL
No Results Yet
NCT04929210 | RECRUITING | PHASE4
405 Participants

A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-08-30
Completion: 2026-08-04
Conditions
Arthritis, Psoriatic
Interventions
DRUG
No Results Yet
NCT04929041 | RECRUITING | PHASE2/PHASE3
427 Participants

Testing the Addition of Radiation Therapy to the Usual Treatment (Immunotherapy With or Without Chemotherapy) for Advanced Stage Non-small Cell Lung Cancer Patients Who Are PD-L1 Negative

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-10-07
Completion: 2027-12-31
Conditions
Lung Adenocarcinoma Lung Adenosquamous Carcinoma Lung Non-Small Cell Carcinoma Stage IIIB Lung Cancer AJCC v8 Stage IIIC Lung Cancer AJCC v8 Stage IV Lung Cancer AJCC v8
Interventions
PROCEDURE BIOLOGICAL OTHER RADIATION
No Results Yet
NCT04926467 | RECRUITING | PHASE2
24 Participants

Chemotherapy + Anakinra in Patients With Pancreatic Adenocarcinoma (PDAC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-07-23
Completion: 2026-06-30
Conditions
Pancreatic Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT04923893 | ACTIVE_NOT_RECRUITING | PHASE3
743 Participants

A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-08-19
Completion: 2029-02-14
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT04921904 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
8 Participants

Abemaciclib Plus Ramucirumab for Esophageal/Gastroesophageal Junction Ca

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-06-11
Completion: 2024-12-31
Conditions
Metastatic Esophageal Adenocarcinoma Metastatic Gastroesophageal Junction Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT04919512 | ACTIVE_NOT_RECRUITING | PHASE2
163 Participants

A Study of TAR-200 in Combination With Cetrelimab and Cetrelimab Alone in Participants With Muscle-Invasive Urothelial Carcinoma of the Bladder

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-07-07
Completion: 2025-01-31
Conditions
Urinary Bladder Neoplasms
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT04919369 | ACTIVE_NOT_RECRUITING | PHASE1
18 Participants

All-Trans Retinoic Acid (ATRA) and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-10-18
Completion: 2026-01-15
Conditions
Metastatic Lung Non-Small Cell Carcinoma Recurrent Lung Non-Small Cell Carcinoma Stage IV Lung Cancer AJCC v8 Stage IVA Lung Cancer AJCC v8 Stage IVB Lung Cancer AJCC v8
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT04918121 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1
5 Participants

A Study of Yutiq Steroid Insert During Glaucoma Tube Implant Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-07-20
Completion: 2027-06-30
Conditions
Glaucoma
Interventions
DRUG
No Results Yet
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