Clinical Trials
743
Participants
A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-08-19
Completion:
2029-02-14
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
8
Participants
Abemaciclib Plus Ramucirumab for Esophageal/Gastroesophageal Junction Ca
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-06-11
Completion:
2024-12-31
Conditions
Metastatic Esophageal Adenocarcinoma
Metastatic Gastroesophageal Junction Adenocarcinoma
Interventions
DRUG
No Results Yet
163
Participants
A Study of TAR-200 in Combination With Cetrelimab and Cetrelimab Alone in Participants With Muscle-Invasive Urothelial Carcinoma of the Bladder
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2022-07-07
Completion:
2025-01-31
Conditions
Urinary Bladder Neoplasms
Interventions
DRUG
BIOLOGICAL
No Results Yet
18
Participants
All-Trans Retinoic Acid (ATRA) and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-10-18
Completion:
2026-01-15
Conditions
Metastatic Lung Non-Small Cell Carcinoma
Recurrent Lung Non-Small Cell Carcinoma
Stage IV Lung Cancer AJCC v8
Stage IVA Lung Cancer AJCC v8
Stage IVB Lung Cancer AJCC v8
Interventions
BIOLOGICAL
DRUG
No Results Yet
5
Participants
A Study of Yutiq Steroid Insert During Glaucoma Tube Implant Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-07-20
Completion:
2027-06-30
Conditions
Glaucoma
Interventions
DRUG
No Results Yet
658
Participants
A Study to Test the Long-term Treatment of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-05-27
Completion:
2026-07-28
Conditions
Hidradenitis Suppurativa
Interventions
DRUG
No Results Yet
17935
Participants
A Study of Vaccination With 9-valent Extraintestinal Pathogenic Escherichia Coli Vaccine (ExPEC9V) in the Prevention of Invasive Extraintestinal Pathogenic Escherichia Coli Disease in Adults Aged 60 Years And Older With a History of Urinary Tract Infection in the Past 2 Years
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-06-30
Completion:
2025-08-27
Conditions
Invasive Extraintestinal Pathogenic Escherichia Coli Disease (IED) Prevention
Interventions
BIOLOGICAL
OTHER
No Results Yet
75
Participants
Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2022-03-28
Completion:
2026-11-30
Conditions
Chronic Lymphocytic Leukemia (CLL)
Interventions
DRUG
No Results Yet
500
Participants
JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2022-01-04
Completion:
2026-06-30
Conditions
Locally Advanced Head and Neck Squamous Cell Carcinoma
Aged
Interventions
DRUG
RADIATION
No Results Yet
80
Participants
A Study of Nipocalimab in Adult Participants With Active Lupus Nephritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2026-01-15
Completion:
2028-02-28
Conditions
Lupus Nephritis
Interventions
OTHER
DRUG
No Results Yet
1054
Participants
A Study of Guselkumab in Participants With Active Psoriatic Arthritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-06-17
Completion:
2024-12-30
Conditions
Arthritis, Psoriatic
Interventions
DRUG
No Results Yet
2210
Participants
Implementing Inclusive Fraction Intervention Classwide
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-09-24
Completion:
2026-08-31
Conditions
Math Learning Difficulty
Interventions
BEHAVIORAL
No Results Yet
102
Participants
A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-07-21
Completion:
2032-12-30
Conditions
Renal Allograft Recipients
Interventions
BIOLOGICAL
DRUG
No Results Yet
20
Participants
Belantamab Mafodotin and Lenalidomide for the Treatment of Multiple Myeloma in Patients With Minimal Residual Disease Positive After Stem Cell Transplant
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2024-08-19
Completion:
2026-09-01
Conditions
Plasma Cell Myeloma
Interventions
BIOLOGICAL
DRUG
No Results Yet
152
Participants
APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-06-22
Completion:
2027-10-31
Conditions
Pancreatic Acinar Cell Carcinoma
Pancreatic Adenosquamous Carcinoma
Pancreatic Squamous Cell Carcinoma
Resectable Pancreatic Acinar Cell Carcinoma
Resectable Pancreatic Adenocarcinoma
Resectable Pancreatic Adenosquamous Carcinoma
Resectable Pancreatic Carcinoma
Interventions
PROCEDURE
DRUG
No Results Yet
198
Participants
Post-Market Clinical Follow-Up onTVT EXACTยฎ Continence System
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2021-07-08
Completion:
2035-09-30
Conditions
Stress Urinary Incontinence
Interventions
DEVICE
No Results Yet
195
Participants
Post Market Clinical Follow-up Study on TVT ABBREVOยฎ Continence System
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2021-09-09
Completion:
2036-09-30
Conditions
Stress Urinary Incontinence
Interventions
DEVICE
No Results Yet
1000
Participants
Ethicon Pelvic Mesh Post Market Clinical Follow-up Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2022-04-13
Completion:
2036-03-30
Conditions
Stress Urinary Incontinence
Pelvic Organ Prolapse
Interventions
DEVICE
No Results Yet
100
Participants
GYNEMESH PS Mesh Post Marketing Clinical Follow-Up Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2021-11-24
Completion:
2031-09-30
Conditions
Pelvic Organ Prolapse
Interventions
DEVICE
No Results Yet
5
Participants
Testing Oral Decitabine and Cedazuridine (ASTX727) in Combination With Venetoclax for Higher-Risk Acute Myeloid Leukemia Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2022-02-10
Completion:
2025-06-06
Conditions
Acute Myeloid Leukemia
Interventions
PROCEDURE
DRUG
No Results Yet
376
Participants
Middle Meningeal Artery Embolization for the Treatment of Subdural Hematomas With TRUFILLยฎ n-BCA
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-05-27
Completion:
2024-08-15
Conditions
Chronic Subdural Hematoma
Interventions
DEVICE
OTHER
No Results Yet
27
Participants
Phase I Study of Anti-CD22 Chimeric Receptor T Cells in Patients With Relapsed/Refractory Hairy Cell Leukemia and Variant
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2022-05-23
Completion:
2036-12-01
Conditions
Hairy Cell Leukemia
Hairy Cell Leukemia Variant
Interventions
BIOLOGICAL
No Results Yet
200
Participants
Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-06-10
Completion:
2028-07-01
Conditions
Metastatic Lung Small Cell Carcinoma
Metastatic Malignant Neoplasm in the Brain
Recurrent Lung Small Cell Carcinoma
Stage IV Lung Cancer AJCC v8
Interventions
PROCEDURE
DRUG
OTHER
RADIATION
No Results Yet
297
Participants
Effectiveness of the EMPOWERโข Modular Pacing System and EMBLEMโข Subcutaneous ICD to Communicate Antitachycardia Pacing
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-07-20
Completion:
2024-05-06
Conditions
Tachycardia, Ventricular
Arrhythmia, Ventricular
Interventions
DEVICE
97
Participants
Follow-up Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2020-12-04
Completion:
2029-09-20
Conditions
X-Linked Retinitis Pigmentosa
Interventions
BIOLOGICAL
No Results Yet
1300
Participants
Collection of Samples USOPTIVAL Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2020-12-30
Completion:
2025-12-30
Conditions
Colorectal Cancer (CRC)
Advanced Adenomas (AA)
Interventions
DIAGNOSTIC_TEST
No Results Yet
286
Participants
Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2024-03-19
Completion:
2025-12-31
Conditions
Attention-Deficit/Hyperactivity Disorder
Interventions
DRUG
No Results Yet
84
Participants
Decitabine/Cedazuridine and Venetoclax in Combination With Ivosidenib or Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-05-24
Completion:
2027-11-29
Conditions
Acute Myeloid Leukemia
Recurrent Acute Myeloid Leukemia
Refractory Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
20
Participants
Simplified IMmunosuppressive Protocol Utilizing Low Dose EnvarsusXR
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-11-23
Completion:
2024-02-23
Conditions
Kidney Transplantation
Kidney Transplant Rejection
Interventions
DRUG
No Results Yet
325
Participants
An Efficacy and Safety Study of ALZ-801 in APOE4/4 Early AD Subjects
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-05-19
Completion:
2024-05-29
Conditions
Early Alzheimer's Disease
Interventions
DRUG
53
Participants
Acalabrutinib and Rituximab for the Treatment of Previously Untreated Mantle Cell Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-06-30
Completion:
2026-08-30
Conditions
Mantle Cell Lymphoma
Interventions
DRUG
BIOLOGICAL
No Results Yet
11
Participants
Erdafitinib for the Treatment of Patients With Castration-Resistant Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-07-15
Completion:
2026-06-30
Conditions
Castration-Resistant Prostate Carcinoma
Castration-Resistant Prostate Carcinoma Refractory to Second-Generation Androgen Receptor Axis-Targeted Agents
Metastatic Malignant Neoplasm in the Bone
Metastatic Prostate Adenocarcinoma
Metastatic Prostate Small Cell Neuroendocrine Carcinoma
Stage IV Prostate Cancer AJCC v8
Stage IVA Prostate Cancer AJCC v8
Stage IVB Prostate Cancer AJCC v8
Interventions
PROCEDURE
DRUG
No Results Yet
125
Participants
Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2022-04-20
Completion:
2027-02-02
Conditions
Ankylosing Spondylitis
Autoimmune Disease
Crohn Disease
Enteropathic Arthritis
Enteropathic Spondylitis
Inflammatory Bowel Disease
Melanoma
Psoriasis
Psoriatic Arthritis
Reactive Arthritis
Rheumatoid Arthritis
Systemic Lupus Erythematosus
Ulcerative Colitis
Interventions
OTHER
No Results Yet
10
Participants
Pegloticase for the Reduction of Uric Acid in Patients With Tumor Lysis Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2022-04-05
Completion:
2025-12-31
Conditions
Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm
Tumor Lysis Syndrome
Interventions
DRUG
No Results Yet
24
Participants
Addition of Cord Blood Tissue-Derived Mesenchymal Stromal Cells to Ruxolitinib for the Treatment of Steroid-Refractory Acute Graft Versus Host Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-02-17
Completion:
2026-03-15
Conditions
Hematopoietic and Lymphoid Cell Neoplasm
Steroid Refractory Graft Versus Host Disease
Interventions
OTHER
DRUG
No Results Yet
30
Participants
Measuring the Effect of Dupilumab Treatment on Mucociliary Clearance (MCC) in Subjects With Moderate to Severe Asthma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2022-10-17
Completion:
2026-07-31
Conditions
Asthma
Interventions
DRUG
OTHER
No Results Yet
14
Participants
Food and Circadian Timing
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2022-04-01
Completion:
2026-03-31
Conditions
Diet, High-Fat
Circadian Rhythm
Interventions
OTHER
No Results Yet
490
Participants
Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-04-05
Completion:
2027-03-19
Conditions
Hematologic Malignancies
Waldenstroms Macroglobulinaemia
Non-Hodgkins Lymphoma
Chronic Lymphocytic Leukaemia
Interventions
DRUG
No Results Yet
140
Participants
A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-03-12
Completion:
2027-04-07
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
490
Participants
Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2021-05-21
Completion:
2026-08-31
Conditions
Gastric Cancer, Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma
Interventions
DRUG
No Results Yet
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