Clinical Trials

NCT04901195 | ACTIVE_NOT_RECRUITING | PHASE3

658 Participants

A Study to Test the Long-term Treatment of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-05-27

Completion: 2026-07-28

Conditions

Hidradenitis Suppurativa

Interventions

DRUG

No Results Yet

NCT04899336 | COMPLETED | PHASE3

17935 Participants

A Study of Vaccination With 9-valent Extraintestinal Pathogenic Escherichia Coli Vaccine (ExPEC9V) in the Prevention of Invasive Extraintestinal Pathogenic Escherichia Coli Disease in Adults Aged 60 Years And Older With a History of Urinary Tract Infection in the Past 2 Years

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-06-30

Completion: 2025-08-27

Conditions

Invasive Extraintestinal Pathogenic Escherichia Coli Disease (IED) Prevention

Interventions

BIOLOGICAL OTHER

No Results Yet

NCT04895436 | RECRUITING | PHASE2

75 Participants

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-03-28

Completion: 2026-11-30

Conditions

Chronic Lymphocytic Leukemia (CLL)

Interventions

DRUG

No Results Yet

NCT04892173 | RECRUITING | PHASE3

500 Participants

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-01-04

Completion: 2026-06-30

Conditions

Locally Advanced Head and Neck Squamous Cell Carcinoma Aged

Interventions

DRUG RADIATION

No Results Yet

NCT04883619 | NOT_YET_RECRUITING | PHASE2

80 Participants

A Study of Nipocalimab in Adult Participants With Active Lupus Nephritis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2026-01-15

Completion: 2028-02-28

Conditions

Lupus Nephritis

Interventions

OTHER DRUG

No Results Yet

NCT04882098 | ACTIVE_NOT_RECRUITING | PHASE3

1054 Participants

A Study of Guselkumab in Participants With Active Psoriatic Arthritis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-06-17

Completion: 2024-12-30

Conditions

Arthritis, Psoriatic

Interventions

DRUG

No Results Yet

NCT04878757 | ENROLLING_BY_INVITATION | NA

2210 Participants

Implementing Inclusive Fraction Intervention Classwide

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-09-24

Completion: 2026-08-31

Conditions

Math Learning Difficulty

Interventions

BEHAVIORAL

No Results Yet

NCT04877288 | RECRUITING | PHASE3

102 Participants

A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-07-21

Completion: 2032-12-30

Conditions

Renal Allograft Recipients

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT04876248 | RECRUITING | PHASE2

20 Participants

Belantamab Mafodotin and Lenalidomide for the Treatment of Multiple Myeloma in Patients With Minimal Residual Disease Positive After Stem Cell Transplant

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-08-19

Completion: 2026-09-01

Conditions

Plasma Cell Myeloma

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT04858334 | RECRUITING | PHASE2

152 Participants

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-06-22

Completion: 2027-10-31

Conditions

Pancreatic Acinar Cell Carcinoma Pancreatic Adenosquamous Carcinoma Pancreatic Squamous Cell Carcinoma Resectable Pancreatic Acinar Cell Carcinoma Resectable Pancreatic Adenocarcinoma Resectable Pancreatic Adenosquamous Carcinoma Resectable Pancreatic Carcinoma

Interventions

PROCEDURE DRUG

No Results Yet

NCT04829994 | ACTIVE_NOT_RECRUITING

198 Participants

Post-Market Clinical Follow-Up onTVT EXACT® Continence System

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2021-07-08

Completion: 2035-09-30

Conditions

Stress Urinary Incontinence

Interventions

DEVICE

No Results Yet

NCT04829357 | RECRUITING

195 Participants

Post Market Clinical Follow-up Study on TVT ABBREVO® Continence System

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2021-09-09

Completion: 2036-09-30

Conditions

Stress Urinary Incontinence

Interventions

DEVICE

No Results Yet

NCT04829175 | RECRUITING

1000 Participants

Ethicon Pelvic Mesh Post Market Clinical Follow-up Registry

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2022-04-13

Completion: 2036-03-30

Conditions

Stress Urinary Incontinence Pelvic Organ Prolapse

Interventions

DEVICE

No Results Yet

NCT04829058 | RECRUITING

100 Participants

GYNEMESH PS Mesh Post Marketing Clinical Follow-Up Study

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2021-11-24

Completion: 2031-09-30

Conditions

Pelvic Organ Prolapse

Interventions

DEVICE

No Results Yet

NCT04817241 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

5 Participants

Testing Oral Decitabine and Cedazuridine (ASTX727) in Combination With Venetoclax for Higher-Risk Acute Myeloid Leukemia Patients

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-02-10

Completion: 2025-06-06

Conditions

Acute Myeloid Leukemia

Interventions

PROCEDURE DRUG

No Results Yet

NCT04816591 | COMPLETED | NA

376 Participants

Middle Meningeal Artery Embolization for the Treatment of Subdural Hematomas With TRUFILL® n-BCA

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-05-27

Completion: 2024-08-15

Conditions

Chronic Subdural Hematoma

Interventions

DEVICE OTHER

No Results Yet

NCT04815356 | RECRUITING | PHASE1

27 Participants

Phase I Study of Anti-CD22 Chimeric Receptor T Cells in Patients With Relapsed/Refractory Hairy Cell Leukemia and Variant

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-05-23

Completion: 2036-12-01

Conditions

Hairy Cell Leukemia Hairy Cell Leukemia Variant

Interventions

BIOLOGICAL

No Results Yet

NCT04804644 | RECRUITING | PHASE3

200 Participants

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-06-10

Completion: 2028-07-01

Conditions

Metastatic Lung Small Cell Carcinoma Metastatic Malignant Neoplasm in the Brain Recurrent Lung Small Cell Carcinoma Stage IV Lung Cancer AJCC v8

Interventions

PROCEDURE DRUG OTHER RADIATION

No Results Yet

NCT04798768 | ACTIVE_NOT_RECRUITING | NA

297 Participants

Effectiveness of the EMPOWER™ Modular Pacing System and EMBLEM™ Subcutaneous ICD to Communicate Antitachycardia Pacing

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-07-20

Completion: 2024-05-06

Conditions

Tachycardia, Ventricular Arrhythmia, Ventricular

Interventions

DEVICE

Results Available

NCT04794101 | ACTIVE_NOT_RECRUITING | PHASE3

97 Participants

Follow-up Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2020-12-04

Completion: 2029-09-20

Conditions

X-Linked Retinitis Pigmentosa

Interventions

BIOLOGICAL

No Results Yet

NCT04792684 | RECRUITING

1300 Participants

Collection of Samples USOPTIVAL Study

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2020-12-30

Completion: 2025-12-30

Conditions

Colorectal Cancer (CRC) Advanced Adenomas (AA)

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04781140 | RECRUITING | PHASE4

286 Participants

Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2024-03-19

Completion: 2025-12-31

Conditions

Attention-Deficit/Hyperactivity Disorder

Interventions

DRUG

No Results Yet

NCT04774393 | RECRUITING | PHASE1/PHASE2

84 Participants

Decitabine/Cedazuridine and Venetoclax in Combination With Ivosidenib or Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-05-24

Completion: 2027-11-29

Conditions

Acute Myeloid Leukemia Recurrent Acute Myeloid Leukemia Refractory Acute Myeloid Leukemia

Interventions

DRUG

No Results Yet

NCT04773392 | TERMINATED | PHASE4

20 Participants

Simplified IMmunosuppressive Protocol Utilizing Low Dose EnvarsusXR

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-11-23

Completion: 2024-02-23

Conditions

Kidney Transplantation Kidney Transplant Rejection

Interventions

DRUG

No Results Yet

NCT04770220 | COMPLETED | PHASE3

325 Participants

An Efficacy and Safety Study of ALZ-801 in APOE4/4 Early AD Subjects

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-05-19

Completion: 2024-05-29

Conditions

Early Alzheimer's Disease

Interventions

DRUG

Results Available

NCT04765111 | ACTIVE_NOT_RECRUITING | PHASE2

53 Participants

Acalabrutinib and Rituximab for the Treatment of Previously Untreated Mantle Cell Lymphoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-06-30

Completion: 2026-08-30

Conditions

Mantle Cell Lymphoma

Interventions

DRUG BIOLOGICAL

No Results Yet

NCT04754425 | ACTIVE_NOT_RECRUITING | PHASE2

11 Participants

Erdafitinib for the Treatment of Patients With Castration-Resistant Prostate Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-07-15

Completion: 2026-06-30

Conditions

Castration-Resistant Prostate Carcinoma Castration-Resistant Prostate Carcinoma Refractory to Second-Generation Androgen Receptor Axis-Targeted Agents Metastatic Malignant Neoplasm in the Bone Metastatic Prostate Adenocarcinoma Metastatic Prostate Small Cell Neuroendocrine Carcinoma Stage IV Prostate Cancer AJCC v8 Stage IVA Prostate Cancer AJCC v8 Stage IVB Prostate Cancer AJCC v8

Interventions

PROCEDURE DRUG

No Results Yet

NCT04751396 | RECRUITING

125 Participants

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2022-04-20

Completion: 2027-02-02

Conditions

Ankylosing Spondylitis Autoimmune Disease Crohn Disease Enteropathic Arthritis Enteropathic Spondylitis Inflammatory Bowel Disease Melanoma Psoriasis Psoriatic Arthritis Reactive Arthritis Rheumatoid Arthritis Systemic Lupus Erythematosus Ulcerative Colitis

Interventions

OTHER

No Results Yet

NCT04745910 | ACTIVE_NOT_RECRUITING | PHASE4

10 Participants

Pegloticase for the Reduction of Uric Acid in Patients With Tumor Lysis Syndrome

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-04-05

Completion: 2025-12-31

Conditions

Hematopoietic and Lymphoid Cell Neoplasm Malignant Solid Neoplasm Tumor Lysis Syndrome

Interventions

DRUG

No Results Yet

NCT04744116 | RECRUITING | EARLY_PHASE1

24 Participants

Addition of Cord Blood Tissue-Derived Mesenchymal Stromal Cells to Ruxolitinib for the Treatment of Steroid-Refractory Acute Graft Versus Host Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-02-17

Completion: 2026-03-15

Conditions

Hematopoietic and Lymphoid Cell Neoplasm Steroid Refractory Graft Versus Host Disease

Interventions

OTHER DRUG

No Results Yet

NCT04743791 | RECRUITING | PHASE4

30 Participants

Measuring the Effect of Dupilumab Treatment on Mucociliary Clearance (MCC) in Subjects With Moderate to Severe Asthma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-10-17

Completion: 2026-07-31

Conditions

Asthma

Interventions

DRUG OTHER

No Results Yet

NCT04743271 | RECRUITING | NA

14 Participants

Food and Circadian Timing

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-04-01

Completion: 2026-03-31

Conditions

Diet, High-Fat Circadian Rhythm

Interventions

OTHER

No Results Yet

NCT04728893 | RECRUITING | PHASE2

490 Participants

Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-04-05

Completion: 2027-03-19

Conditions

Hematologic Malignancies Waldenstroms Macroglobulinaemia Non-Hodgkins Lymphoma Chronic Lymphocytic Leukaemia

Interventions

DRUG

No Results Yet

NCT04722146 | ACTIVE_NOT_RECRUITING | PHASE1

140 Participants

A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-03-12

Completion: 2027-04-07

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT04704934 | ACTIVE_NOT_RECRUITING | PHASE3

490 Participants

Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-05-21

Completion: 2026-08-31

Conditions

Gastric Cancer, Adenocarcinoma Gastroesophageal Junction Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT04703101 | RECRUITING | PHASE1

25 Participants

Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-02-11

Completion: 2026-10-01

Conditions

Locally Advanced Rectal Carcinoma Rectal Adenocarcinoma Stage II Rectal Cancer AJCC v8 Stage IIA Rectal Cancer AJCC v8 Stage IIB Rectal Cancer AJCC v8 Stage IIC Rectal Cancer AJCC v8 Stage III Rectal Cancer AJCC v8 Stage IIIA Rectal Cancer AJCC v8 Stage IIIB Rectal Cancer AJCC v8 Stage IIIC Rectal Cancer AJCC v8

Interventions

DRUG RADIATION OTHER BEHAVIORAL PROCEDURE

No Results Yet

NCT04696809 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

40 Participants

A Study of Teclistamab in Japanese Participants With Relapsed or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-02-22

Completion: 2026-04-22

Conditions

Hematologic Malignancies

Interventions

DRUG

No Results Yet

NCT04696575 | RECRUITING | PHASE2

28 Participants

Lamivudine in Combination With Chemoimmunotherapy for the Treatment of Extensive Stage Small Cell Lung Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-07-02

Completion: 2026-07-01

Conditions

Extensive Stage Lung Small Cell Carcinoma

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT04684563 | ACTIVE_NOT_RECRUITING | PHASE1

72 Participants

huCART19-IL18 in CD19+ Cancers

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-05-06

Completion: 2036-05-31

Conditions

Chronic Lymphocytic Leukemia Non-hodgkin Lymphoma Acute Lymphoblastic Leukemia

Interventions

BIOLOGICAL

No Results Yet

NCT04676594 | ACTIVE_NOT_RECRUITING

400 Participants

Genentech Validation Tool for Pulmonary Fibrosis

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2020-10-04

Completion: 2026-08-31

Conditions

Interstitial Lung Disease

No Results Yet