Clinical Trials
50
Participants
Haploidentical BMT With Post-Transplant Cyclophosphamide and Bendamustine
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-11-29
Completion:
2025-08-01
Conditions
Acute Lymphoblastic Leukemia
Acute Myelogenous Leukemia
Myelodysplastic Syndromes
Chronic Myelogenous Leukemia
Lymphoma,Non-Hodgkin
Lymphoma, Hodgkin
Lymphoma, Follicular
Marginal Zone Lymphoma
Large Cell Lymphoma
Mantle-Cell Lymphoma
Gray Zone Lymphoma
Burkitt Lymphoma
High Risk Undifferentiated Acute Leukemia
Interventions
DRUG
No Results Yet
60
Participants
Alpha/Beta T and CD19+ Depleted Peripheral Stem Cells for Patients With Primary Immunodeficiencies
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-12-31
Completion:
2026-11-30
Conditions
Immunodeficiencies
Immune Dysregulation Syndromes
Interventions
DEVICE
No Results Yet
59
Participants
A Study of Brentuximab Vedotin + Adriamycin, Vinblastine, and Dacarbazine in Pediatric Participants With Advanced Stage Newly Diagnosed Hodgkin Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2017-09-06
Completion:
2020-05-05
Conditions
Hodgkin Disease
Interventions
DRUG
460
Participants
INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2017-02-09
Completion:
2028-02-01
Conditions
Glioblastoma
Interventions
DRUG
No Results Yet
51
Participants
CIMAvax Vaccine, Nivolumab, and Pembrolizumab in Treating Patients With Advanced Non-small Cell Lung Cancer or Squamous Head and Neck Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-12-22
Completion:
2025-05-23
Conditions
Advanced Head and Neck Squamous Cell Carcinoma
Lung Non-Small Cell Carcinoma
Metastatic Lung Non-Small Cell Carcinoma
PD-L1 Positive
Recurrent Head and Neck Squamous Cell Carcinoma
Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
Stage III Lung Cancer AJCC v8
Stage IIIA Lung Cancer AJCC v8
Stage IIIB Lung Cancer AJCC v8
Stage IIIC Lung Cancer AJCC v8
Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
Stage IV Lung Cancer AJCC v8
Stage IVA Lung Cancer AJCC v8
Stage IVB Lung Cancer AJCC v8
Unresectable Lung Non-Small Cell Carcinoma
Advanced Squamous Non-Small Cell Lung Carcinoma
Interventions
OTHER
BIOLOGICAL
No Results Yet
70
Participants
Safety Study of MELK Inhibitor to Treat Patients With Advanced Breast Cancer and Triple Negative Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2017-05-29
Completion:
2027-09-30
Conditions
Relapsed/Refractory Locally Advanced or Metastatic Breast Cancer and Triple Negative Breast Cancer
Interventions
DRUG
No Results Yet
63
Participants
Mild TBI Assessment & Rehabilitation
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2017-03-09
Completion:
2025-10-31
Conditions
Brain Injuries, Traumatic
Interventions
BEHAVIORAL
OTHER
DEVICE
No Results Yet
3613
Participants
Memory Gel and Shape Combined Cohort
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-09-01
Completion:
2031-06-16
Conditions
Primary Breast Augmentation
Primary Breast Reconstruction
Revision Breast Augmentation
Revision Breast Reconstruction
Interventions
DEVICE
PROCEDURE
No Results Yet
177
Participants
Effect of Soluble Corn Fiber Supplementation for 1 Year on Bone Metabolism in Adolescents
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2020-02-10
Completion:
2025-04-30
Conditions
Osteoporosis
Interventions
DIETARY_SUPPLEMENT
COMBINATION_PRODUCT
413
Participants
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of JNJ-63723283, an Anti-PD-1 Monoclonal Antibody, in Participants With Advanced Cancers
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-11-21
Completion:
2023-11-17
Conditions
Neoplasms
Interventions
DRUG
No Results Yet
123
Participants
FOLFIRI or Modified FOLFIRI and Veliparib as Second Line Therapy in Treating Patients With Metastatic Pancreatic Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-09-01
Completion:
2019-05-01
Conditions
Metastatic Pancreatic Adenocarcinoma
Recurrent Pancreatic Carcinoma
Stage IV Pancreatic Cancer AJCC v6 and v7
Interventions
DRUG
OTHER
40
Participants
REVIVE: Reducing Exsanguination Via In-Vivo Expandable Foam
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2025-08-07
Completion:
2026-10-31
Conditions
Hemorrhagic Shock
Trauma
Exsanguinating Hemorrhage
Shock; Traumatic
Interventions
DEVICE
No Results Yet
1200
Participants
Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-11-17
Completion:
2027-10-22
Conditions
Metastatic Castration-Resistant Prostate Cancer
Interventions
BIOLOGICAL
DRUG
OTHER
No Results Yet
540
Participants
14022 ATTUNE Cementless RP Clinical Performance Evaluation
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-09-01
Completion:
2027-09-01
Conditions
Osteoarthritis
Interventions
DEVICE
No Results Yet
444
Participants
Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2017-06-23
Completion:
2023-05-09
Conditions
Fallopian Tube High Grade Serous Adenocarcinoma
Ovarian High Grade Serous Adenocarcinoma
Ovarian Seromucinous Carcinoma
Primary Peritoneal High Grade Serous Adenocarcinoma
Recurrent Fallopian Tube Carcinoma
Recurrent Fallopian Tube Clear Cell Adenocarcinoma
Recurrent Fallopian Tube Endometrioid Adenocarcinoma
Recurrent Fallopian Tube Undifferentiated Carcinoma
Recurrent Ovarian Carcinoma
Recurrent Ovarian Clear Cell Adenocarcinoma
Recurrent Ovarian Endometrioid Adenocarcinoma
Recurrent Ovarian Undifferentiated Carcinoma
Recurrent Platinum-Resistant Fallopian Tube Carcinoma
Recurrent Platinum-Resistant Ovarian Carcinoma
Recurrent Platinum-Resistant Primary Peritoneal Carcinoma
Recurrent Primary Peritoneal Carcinoma
Recurrent Primary Peritoneal Clear Cell Adenocarcinoma
Recurrent Primary Peritoneal Endometrioid Adenocarcinoma
Recurrent Primary Peritoneal Undifferentiated Carcinoma
Interventions
DRUG
BIOLOGICAL
PROCEDURE
OTHER
960
Participants
Metastatic Tumor Research and Outcomes Network
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2017-11-15
Completion:
2025-12-31
Conditions
Metastatic Spine Tumor
No Results Yet
13
Participants
TG4010 and Nivolumab in Patients With Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-12-14
Completion:
2021-02-24
Conditions
Recurrent Non-Small Cell Lung Carcinoma
Stage I Non-Small Cell Lung Cancer
Stage II Non-Small Cell Lung Cancer
Stage IIIA Non-Small Cell Lung Cancer
Stage IIIB Non-Small Cell Lung Cancer
Stage IV Non-Small Cell Lung Cancer
Interventions
BIOLOGICAL
537
Participants
An Observational Prospective Long-term Exposure Registry of Adult Patients With Moderate-to-Severe Ulcerative Colitis
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2016-12-16
Completion:
2026-12-10
Conditions
Ulcerative Colitis
No Results Yet
1350
Participants
Primary Tumor Research and Outcomes Network
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2016-10-31
Completion:
2025-12-31
Conditions
Spinal Column Tumor
No Results Yet
500
Participants
Molecular Analysis of Childhood and Adolescent Melanocytic Lesions
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2016-05-31
Completion:
2031-05-31
Conditions
Melanoma
No Results Yet
18
Participants
Matched Paired Pharmacodynamics and Feasibility Study of Durvalumab in Combination With Chemotherapy in Frontline Ovarian Cancer (N-Dur)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-07-06
Completion:
2025-12-31
Conditions
Stage III Fallopian Tube Cancer AJCC v7
Stage III Ovarian Cancer AJCC v6 and v7
Stage III Primary Peritoneal Cancer AJCC v7
Stage IIIA Fallopian Tube Cancer AJCC v7
Stage IIIA Ovarian Cancer AJCC v6 and v7
Stage IIIA Primary Peritoneal Cancer AJCC v7
Stage IIIB Fallopian Tube Cancer AJCC v7
Stage IIIB Ovarian Cancer AJCC v6 and v7
Stage IIIB Primary Peritoneal Cancer AJCC v7
Stage IIIC Fallopian Tube Cancer AJCC v7
Stage IIIC Ovarian Cancer AJCC v6 and v7
Stage IIIC Primary Peritoneal Cancer AJCC v7
Stage IV Fallopian Tube Cancer AJCC v6 and v7
Stage IV Ovarian Cancer AJCC v6 and v7
Stage IV Primary Peritoneal Cancer AJCC v7
Interventions
DRUG
BIOLOGICAL
OTHER
No Results Yet
400
Participants
A Study of the Safety and Effectiveness of the Mentor Larger Size MemoryGel Ultra High Profile Breast Implants in Subjects Who Are Undergoing Primary Breast Reconstruction or Revision Reconstruction
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-04-01
Completion:
2029-01-31
Conditions
Breast Reconstruction, Revision Breast Reconstruction
Interventions
DEVICE
No Results Yet
230
Participants
Salvage Radiation Therapy in Treating Patients With Metastatic Cancer That Has Progressed After Systemic Immunotherapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-05-25
Completion:
2026-05-30
Conditions
Hematopoietic and Lymphoid Cell Neoplasm
Metastatic Malignant Solid Neoplasm
Interventions
RADIATION
OTHER
No Results Yet
39
Participants
Effectiveness of Dry Needling and Physical Therapy Versus Physical Therapy Alone Following Shoulder Stabilization Repair
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-03-31
Completion:
2017-12-31
Conditions
Shoulder Pain
Interventions
DEVICE
196
Participants
Abiraterone Acetate, Prednisone, and Apalutamide With or Without Ipilimumab or Cabazitaxel and Carboplatin in Treating Patients With Metastatic Castration-Resistant Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-05-18
Completion:
2026-03-31
Conditions
Castration Levels of Testosterone
Castration-Resistant Prostate Carcinoma
Metastatic Prostate Carcinoma
PSA Progression
Stage IV Prostate Adenocarcinoma AJCC v7
Interventions
DRUG
BIOLOGICAL
OTHER
No Results Yet
236
Participants
LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2017-01-06
Completion:
2023-10-31
Conditions
Leukodystrophy
White Matter Disease
4H Syndrome
Adrenoleukodystrophy
AMN
ALD
ALD (Adrenoleukodystrophy)
X-linked Adrenoleukodystrophy
X-ALD
Adrenomyeloneuropathy
Aicardi Goutieres Syndrome
AGS
Alexander Disease
Alexanders Leukodystrophy
AxD
ADLD
Canavan Disease
CTX
Cerebrotendinous Xanthomatoses
Krabbe Disease
GALC Deficiency
Globoid Leukodystrophy
TUBB4A-Related Leukodystrophy
H-ABC - Hypomyelination, Atrophy of Basal Ganglia and Cerebellum
HBSL
HBSL - Hypomyelination, Brain Stem, Spinal Cord, Leg Spasticity
LBSL
Leukoencephalopathy With Brain Stem and Spinal Cord Involvement and High Lactate Syndrome (Disorder)
Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation
ALSP
CSF1R Gene Mutation
HCC - Hypomyelination and Congenital Cataract
MLC1
Megalencephalic Leukoencephalopathy With Subcortical Cysts 1
MLD
Metachromatic Leukodystrophy
PMD
Pelizaeus-Merzbacher Disease
PLP1 Null Syndrome
PLP1 Gene Duplication | Blood or Tissue | Mutations
Pelizaeus-Merzbacher-Like Disease, 1
Peroxisomal Biogenesis Disorder
Zellweger Syndrome
Refsum Disease
Salla Disease
Sialic Storage Disease
Sjรถgren
Sjogren-Larsson Syndrome
Van Der Knapp Disease
Vanishing White Matter Disease
Charcot-Marie-Tooth
CMT
Mct8 (Slc16A2)-Specific Thyroid Hormone Cell Transporter Deficiency
Allan-Herndon-Dudley Syndrome
Cadasil
Cockayne Syndrome
Multiple Sulfatase Deficiency
Gangliosidoses
GM2 Gangliosidosis
BPAN
Labrune Syndrome
LCC
Mucopolysaccharidoses
TBCK-Related Intellectual Disability Syndrome
85
Participants
Behavioral Activation Therapy and Nicotine Replacement Therapy in Increasing Smoking Cessation
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-08-05
Completion:
2025-12-31
Conditions
Cigarette Smoker
Tobacco Use Disorder
Interventions
BEHAVIORAL
OTHER
DRUG
No Results Yet
80
Participants
Nivolumab and Radiation Therapy With or Without Ipilimumab in Treating Patients With Brain Metastases From Non-small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-12-16
Completion:
2027-12-31
Conditions
Metastatic Malignant Neoplasm in the Brain
Stage IV Non-Small Cell Lung Cancer AJCC v7
Interventions
PROCEDURE
BIOLOGICAL
OTHER
RADIATION
No Results Yet
272
Participants
Vigilant ObservatIon of GlIadeL WAfer ImplaNT Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2016-04-26
Completion:
2025-06-23
Conditions
CNS Tumor
No Results Yet
20
Participants
Utilizing Holmium Laser for FURS Renal Stone Lithotripsy Comparing Stone Breaking vs. Stone Dusting Settings
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-02-29
Completion:
2017-01-31
Conditions
Stone Clearance
Interventions
DEVICE
60
Participants
Trametinib and Docetaxel in Treating Patients With Recurrent or Stage IV KRAS Mutation Positive Non-small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-07-18
Completion:
2019-05-15
Conditions
KRAS Gene Mutation
Recurrent Lung Non-Small Cell Carcinoma
Stage IV Lung Non-Small Cell Cancer AJCC v7
Interventions
DRUG
OTHER
10
Participants
A Study of Haploidentical Bone Marrow Transplant for Patients With Hematologic Malignancies
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2012-09-21
Completion:
2016-05-12
Conditions
Hematologic Malignancies
Interventions
DRUG
751
Participants
Study of Amivantamab, a Human Bispecific EGFR and cMet Antibody, in Participants With Advanced Non-Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-05-24
Completion:
2026-12-31
Conditions
Non-Small-Cell Lung Cancer
Interventions
DRUG
No Results Yet
325
Participants
Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-06-01
Completion:
2023-06-30
Conditions
Alveolar Rhabdomyosarcoma
Botryoid-Type Embryonal Rhabdomyosarcoma
Embryonal Rhabdomyosarcoma
Rhabdomyosarcoma
Sclerosing Rhabdomyosarcoma
Spindle Cell Rhabdomyosarcoma
Interventions
DRUG
BIOLOGICAL
OTHER
RADIATION
117
Participants
Open-Label, Randomised, Multi-Drug, Biomarker-Directed, Phase 1b Study in Pts w/ Muscle Invasive Bladder Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-12-28
Completion:
2020-03-18
Conditions
Muscle Invasive Bladder Cancer
Interventions
DRUG
No Results Yet
1503
Participants
An Efficacy and Safety Study of JNJ-56021927 (Apalutamide) in High-risk Prostate Cancer Subjects Receiving Primary Radiation Therapy: ATLAS
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2015-11-19
Completion:
2026-06-30
Conditions
Prostatic Neoplasms
Interventions
DRUG
RADIATION
No Results Yet
1301
Participants
Physician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2015-11-10
Completion:
2023-09-15
Conditions
Clinical Stage III Cutaneous Melanoma AJCC v8
Clinical Stage IV Cutaneous Melanoma AJCC v8
Metastatic Cutaneous Melanoma
Metastatic Mucosal Melanoma
Metastatic Non-Cutaneous Melanoma
Non-Cutaneous Melanoma
Recurrent Cutaneous Melanoma
Recurrent Mucosal Melanoma
Recurrent Non-Cutaneous Melanoma
Interventions
PROCEDURE
BIOLOGICAL
OTHER
61
Participants
Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2015-09-03
Completion:
2021-04-01
Conditions
Head and Neck Squamous Cell Carcinoma
Metastatic Pancreatic Adenocarcinoma
Non-Resectable Cholangiocarcinoma
Pancreatic Adenocarcinoma
Recurrent Gallbladder Carcinoma
Recurrent Non-Small Cell Lung Carcinoma
Stage III Pancreatic Cancer
Stage IIIA Gallbladder Cancer
Stage IIIA Non-Small Cell Lung Cancer
Stage IIIB Gallbladder Cancer
Stage IIIB Non-Small Cell Lung Cancer
Stage IV Gallbladder Cancer
Stage IV Non-Small Cell Lung Cancer
Stage IV Pancreatic Cancer
Unresectable Gallbladder Carcinoma
Unresectable Pancreatic Cancer
Interventions
DRUG
OTHER
BIOLOGICAL
No Results Yet
237
Participants
Long-term Outcomes of Children With Hypoplastic Left Heart Syndrome and the Impact of Norwood Shunt Type
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2015-06-30
Completion:
2020-10-31
Conditions
Heart Defects
32
Participants
Differing Levels of Hypoglycemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2015-07-31
Completion:
2026-09-30
Conditions
Hypoglycemia
Interventions
DEVICE
No Results Yet
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