Clinical Trials

Showing trials with last updates posted in 2024.

NCT05694715 | RECRUITING | PHASE1
24 Participants

Combination Therapy in Cancers With Mutations in DNA Repair Genes

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2023-05-23
Completion: 2028-01-31
Conditions
Metastatic Solid Tumor BRCA1 Mutation BRCA2 Mutation ATM Gene Mutation PALB2 Gene Mutation
Interventions
DRUG
No Results Yet
NCT05673304 | RECRUITING | NA
30 Participants

Preoperative Boost Associated With Neoadjuvant Chemotherapy in Luminal B Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2023-05-24
Completion: 2027-12-31
Conditions
Breast Cancer Radiotherapy
Interventions
RADIATION
No Results Yet
NCT05656027 | COMPLETED | PHASE3
469 Participants

Phase 3 Evaluation of the Safety and Efficacy of LNZ101 for the Treatment of Presbyopia

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2022-12-19
Completion: 2023-12-15
Conditions
Presbyopia Refractive Error Near Vision Miosis Eye Diseases
Interventions
DRUG
No Results Yet
NCT05655195 | RECRUITING | NA
50 Participants

Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2022-12-14
Completion: 2025-12-01
Conditions
Alzheimer Disease Alzheimer Disease, Early Onset Alzheimer Disease, Late Onset Alzheimer's Disease (Incl Subtypes) Alzheimer's Alzheimer's Disease
Interventions
DEVICE
No Results Yet
NCT05650775 | COMPLETED | PHASE1
16 Participants

Biomarkers of ADHD Treatment Response

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2023-02-17
Completion: 2024-03-30
Conditions
ADHD
Interventions
DRUG
No Results Yet
NCT05643287 | NOT_YET_RECRUITING | NA
75 Participants

The Effect of Time on the Outcome of Periodontal Treatment.

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2025-02-03
Completion: 2025-12-31
Conditions
Periodontitis
Interventions
PROCEDURE
No Results Yet
NCT05639348 | COMPLETED
993 Participants

Validation of a Risk Assessment Model for Postoperative Delirium Based on Artificial Intelligence

Study Type: OBSERVATIONAL
Last Updated: 2024-12-18
Start Date: 2022-11-21
Completion: 2024-06-15
Conditions
Postoperative Delirium (POD)
Interventions
OTHER
No Results Yet
NCT05625425 | RECRUITING | NA
200 Participants

Wayfinding Intervention and Long-Term Memory

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2024-01-01
Completion: 2026-12-31
Conditions
Long-Term Memory Decline Mild Cognitive Impairment
Interventions
BEHAVIORAL
No Results Yet
NCT05622201 | RECRUITING | PHASE2
120 Participants

A Randomized Controlled Trial With Rituximab for Psychotic Disorder in Adults

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2023-03-21
Completion: 2026-06-30
Conditions
Schizophrenia Spectrum and Other Psychotic Disorders
Interventions
DRUG
No Results Yet
NCT05617872 | RECRUITING | NA
75 Participants

Vinegar-induced Collection of Duodenal Pancreatic Juice Via Endoscopic Ultrasound

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2022-12-30
Completion: 2025-01-31
Conditions
Pancreatic Cancer
Interventions
DRUG
No Results Yet
NCT05603741 | ACTIVE_NOT_RECRUITING | PHASE4
155 Participants

Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2022-11-10
Completion: 2027-01-31
Conditions
Ehlers-Danlos Syndrome Anesthesia, Local
Interventions
DRUG
No Results Yet
NCT05586737 | COMPLETED | PHASE2
15 Participants

Immunomodulatory Therapy in Women With Autoimmune Premature Ovarian Insufficiency

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2019-04-29
Completion: 2024-12-15
Conditions
Autoimmune Diseases Premature Ovarian Insufficiency
Interventions
DRUG
No Results Yet
NCT05583448 | ENROLLING_BY_INVITATION
93 Participants

MDR ExploR Radial Head System PMCF

Study Type: OBSERVATIONAL
Last Updated: 2024-12-18
Start Date: 2022-08-16
Completion: 2026-08-16
Conditions
Elbow Injury
Interventions
DEVICE
No Results Yet
NCT05562960 | RECRUITING | NA
20 Participants

Plasmapheresis in Amyotrophic Lateral Sclerosis With Autoantibody Against NRIP

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2023-05-01
Completion: 2025-03-31
Conditions
Amyotrophic Lateral Sclerosis Plasmapheresis
Interventions
PROCEDURE
No Results Yet
NCT05561244 | TERMINATED | NA
45 Participants

Weekly Monitoring Strategy of Capillary INR Versus Monthly Monitoring Strategy of Venous INR in Elderly Patients in a Nursing Home.

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2022-11-18
Completion: 2024-12-13
Conditions
Atrial Fibrillation Deep Vein Thrombosis Stroke
Interventions
DEVICE
No Results Yet
NCT05553938 | RECRUITING | PHASE1
60 Participants

Effects of Acute and Chronic Empagliflozin Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2023-08-04
Completion: 2025-11-30
Conditions
Heart Failure
Interventions
DRUG
No Results Yet
NCT05467735 | TERMINATED | NA
20 Participants

Above-Knee-High Application of Lower Limb Compression and Its Impact on Clinical Outcome in Patients Hospitalized With Heart Failure Exacerbation.

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2022-04-30
Completion: 2024-09-10
Conditions
Heart Failure; With Decompensation Lower Extremity Edema Heart Failure,Congestive
Interventions
OTHER
No Results Yet
NCT05456360 | TERMINATED | PHASE2/PHASE3
89 Participants

Implementation of Digital Vital Sign Monitoring to Decrease Sleep Interruption and Enhance Recovery in Phase II of the PROmoting Sleep, Patient Engagement and Recovery (PROSPER) Project

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2023-03-01
Completion: 2023-10-30
Conditions
Sleep
Interventions
DEVICE DRUG
NCT05429476 | COMPLETED | PHASE3
234 Participants

EXtending the Time Window for Thrombolysis in Posterior Circulation Stroke Without Early CT Signs

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2022-08-17
Completion: 2024-08-15
Conditions
Stroke, Acute Ischemic
Interventions
DRUG
No Results Yet
NCT05415501 | RECRUITING | NA
104 Participants

Sentence Production Training in Aphasia

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2021-08-01
Completion: 2026-05-30
Conditions
Aphasia
Interventions
BEHAVIORAL
No Results Yet
NCT05412342 | COMPLETED
718 Participants

Characterizing the Association Between Preoperative Depressive Symptoms and Opioid Use/Misuse After Surgery

Study Type: OBSERVATIONAL
Last Updated: 2024-12-18
Start Date: 2019-05-10
Completion: 2024-03-03
Conditions
Opioid Use
No Results Yet
NCT05373615 | COMPLETED | PHASE1
14 Participants

Cefiderocol Plasma Concentrations in Patients Receiving Renal Replacement Therapy

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2022-07-25
Completion: 2024-11-20
Conditions
Pharmacokinetics
Interventions
DRUG
No Results Yet
NCT05368974 | RECRUITING
100 Participants

The Treatment in Pregnancy for Hepatitis C ("TiP-HepC") Registry

Study Type: OBSERVATIONAL
Last Updated: 2024-12-18
Start Date: 2022-02-11
Completion: 2026-06-30
Conditions
Hepatitis C
Interventions
DRUG
No Results Yet
NCT05339035 | COMPLETED | NA
62 Participants

Digital Game Addiction in Adolescents

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2023-02-03
Completion: 2023-12-26
Conditions
Digital Technology Behavior, Addictive Adolescent Motivation
Interventions
BEHAVIORAL
No Results Yet
NCT05298904 | ACTIVE_NOT_RECRUITING
177 Participants

Pro-active Genetic Testing in Kidney Transplant Patients

Study Type: OBSERVATIONAL
Last Updated: 2024-12-18
Start Date: 2022-03-28
Completion: 2037-03-01
Conditions
Kidney Transplant
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05290597 | RECRUITING | PHASE1
84 Participants

A Phase 1, Open-label, Multicenter, Dose Escalation Study of IBI363 (PD1-IL2m) in Subjects with Advanced Solid Malignancies or Lymphomas

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2022-08-22
Completion: 2026-06-30
Conditions
Solid Malignancies or Lymphomas
Interventions
BIOLOGICAL
No Results Yet
NCT05268887 | RECRUITING | NA
40 Participants

High Frequency Light, Sound, and Tactile Stimulation to Improve Motor and Cognitive Deficits in Parkinson's Disease

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2022-02-09
Completion: 2025-11-01
Conditions
Parkinson Disease
Interventions
DEVICE
No Results Yet
NCT05266001 | TERMINATED | PHASE3
141 Participants

GM-CSF for Reversal of Immunoparalysis in Pediatric Sepsis-induced MODS

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2022-06-14
Completion: 2024-12-01
Conditions
Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome
Interventions
DRUG OTHER
No Results Yet
NCT05246930 | COMPLETED
43 Participants

Evaluating the Use of a Device Called Impulse Oscillometry in Participants With Vocal Cord Disorders or Asthma

Study Type: OBSERVATIONAL
Last Updated: 2024-12-18
Start Date: 2022-06-15
Completion: 2024-06-01
Conditions
Breathing, Mouth Lung Function Decreased Vocal Cord Dysfunction Laryngeal Obstruction Asthma
Interventions
DEVICE
No Results Yet
NCT05185180 | ACTIVE_NOT_RECRUITING
50 Participants

Effects of Epigenetic Regulation in Chronic Pelvic Pain Syndrome

Study Type: OBSERVATIONAL
Last Updated: 2024-12-18
Start Date: 2021-10-11
Completion: 2025-06-30
Conditions
Chronic Pelvic Pain
No Results Yet
NCT05184894 | COMPLETED | NA
50 Participants

A Study of Acute Kidney Injury in Care Transitions

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2022-01-17
Completion: 2023-10-31
Conditions
Acute Kidney Injury
Interventions
BEHAVIORAL
NCT05180552 | WITHDRAWN | NA
0 Participants

The HEALiX: Comparing the Efficacy of the HEALiX Device With Wrist Restraints in a Critical Care Setting

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2028-08-10
Completion: 2028-12-31
Conditions
Safety Issues Device Dislodgement Device Intolerance Device Ineffective
Interventions
DEVICE
No Results Yet
NCT05172700 | APPROVED_FOR_MARKETING

Expanded Access Program for Pirtobrutinib for Participants With B-Cell Cancer

Study Type: EXPANDED_ACCESS
Last Updated: 2024-12-18
Conditions
Leukemia, Lymphocytic, Chronic, B-Cell Lymphoma, Lymphocytic, Small Lymphoma, Mantle-Cell Waldenstrom Macroglobulinemia Ritcher's Transformation, Syndrome
Interventions
DRUG
No Results Yet
NCT05166811 | COMPLETED | PHASE2
52 Participants

Timely Intravenous Magnesium for Asthma in Children

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2022-09-12
Completion: 2023-05-31
Conditions
Asthma
Interventions
DRUG
NCT05164367 | COMPLETED | EARLY_PHASE1
10 Participants

Pharmacokinetics of Atropine Oral Gel

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2022-10-01
Completion: 2023-06-30
Conditions
Cerebral Palsy Sialorrhea
Interventions
DRUG
No Results Yet
NCT05144061 | COMPLETED | PHASE1
28 Participants

A First-in-human Study of HRS2398 Tablets in Subjects With Advanced Malignant Tumors

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2021-12-20
Completion: 2024-02-21
Conditions
Advanced Malignant Tumor
Interventions
DRUG
No Results Yet
NCT05143866 | COMPLETED | NA
44 Participants

A Pilot Study of Evidence-based Guided Self-help for the Treatment of Binge Eating

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2022-02-15
Completion: 2024-09-30
Conditions
Binge-Eating Disorder Binge Eating
Interventions
BEHAVIORAL
No Results Yet
NCT05141487 | RECRUITING
16 Participants

Feasibility of Triggered Sacral Neuromodulation for Neurogenic Bladder

Study Type: OBSERVATIONAL
Last Updated: 2024-12-18
Start Date: 2022-10-03
Completion: 2025-10-29
Conditions
Urinary Incontinence Urinary Bladder, Neurogenic
Interventions
DEVICE
No Results Yet
NCT05088694 | ENROLLING_BY_INVITATION | NA
1500 Participants

The Optimization and Evaluation of the Extremism and Intolerance Curriculum for the Kingdom of Bahrain.

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2021-11-01
Completion: 2025-12-31
Conditions
Norm, Social Literacy Resistance Skills Beliefs About Consequences Decision Making Skills Empathy Tolerance Open Mindedness Active Citizenship Anti-extremism
Interventions
BEHAVIORAL
No Results Yet
NCT05065281 | COMPLETED | NA
554 Participants

Responding to Elder Abuse in GERiAtric Care: Educational Intervention

Study Type: INTERVENTIONAL
Last Updated: 2024-12-18
Start Date: 2021-09-16
Completion: 2024-11-18
Conditions
Healthy
Interventions
OTHER
No Results Yet
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