Pro-active Genetic Testing in Kidney Transplant Patients

NCT ID: NCT05298904

Last Updated: 2024-12-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

177 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-03-28

Study Completion Date

2038-03-01

Brief Summary

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The purpose of this study is to determine the prevalence of genetic mutations that increase the risk of cancer and other medically actionable diseases in kidney transplant patients and to assess the impact of genetic testing on subsequent surveillance for cancer.

Detailed Description

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Conditions

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Kidney Transplant

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Kidney Transplants

Kidney transplant patients who are within one-year post transplant.

Genetic Health Screen Panel

Intervention Type DIAGNOSTIC_TEST

This panel covers cardiomyopathy genes, and cancer genes. The results of this panel are reported as Positive (pathogenic or likely pathogenic mutation identified in one or more genes) or Negative (no pathogenic/likely pathogenic mutations identified).

Interventions

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Genetic Health Screen Panel

This panel covers cardiomyopathy genes, and cancer genes. The results of this panel are reported as Positive (pathogenic or likely pathogenic mutation identified in one or more genes) or Negative (no pathogenic/likely pathogenic mutations identified).

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

\- Post transplant Kidney and Kidney Pancreas recipients.

Exclusion Criteria

* Simultaneous Liver Kidney Transplant.
* Simultaneous Heart Kidney Transplant.
* Non renal transplant history.
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Girish K. Mour

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Girish Mour, MD

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Locations

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Mayo Clinic Arizona

Scottsdale, Arizona, United States

Site Status

Countries

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United States

Related Links

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Other Identifiers

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NCI-2022-02382

Identifier Type: REGISTRY

Identifier Source: secondary_id

21-009697

Identifier Type: -

Identifier Source: org_study_id