Clinical Trials

Showing trials with last updates posted in 2024.

NCT03562975 | COMPLETED
18 Participants

Upper Extremity Function in Multiple Sclerosis Patients With Advanced Disability Treated With Ocrevus

Study Type: OBSERVATIONAL
Last Updated: 2024-12-10
Start Date: 2018-07-23
Completion: 2023-01-11
Conditions
Multiple Sclerosis Pathologic Processes Demyelinating Diseases Nervous System Diseases Autoimmune Diseases Immune System Diseases Primary Progressive Multiple Sclerosis Relapsing Remitting Multiple Sclerosis
Interventions
DRUG
NCT03562494 | COMPLETED | PHASE1
14 Participants

VY-AADC02 for Parkinson's Disease With Motor Fluctuations (RESTORE-1)

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2018-10-17
Completion: 2024-10-30
Conditions
Parkinson's Disease
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT03546556 | TERMINATED | EARLY_PHASE1
10 Participants

18-FLT PET/MR Imaging to Predict Graft Failure and GVHD in Bone Marrow Transplant Patients

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2017-01-01
Completion: 2020-03-12
Conditions
Graft Vs Host Disease
Interventions
DRUG
No Results Yet
NCT03532126 | COMPLETED
91 Participants

A 52-week Clinical Investigation of Princess® VOLUME PLUS Lidocaine in Subjects With Midface Volume Deficit

Study Type: OBSERVATIONAL
Last Updated: 2024-12-10
Start Date: 2018-03-28
Completion: 2019-07-24
Conditions
Midface Volume Deficit
Interventions
DEVICE
No Results Yet
NCT03494790 | COMPLETED
955 Participants

Markers of Inflammation and Metabolism in the ER

Study Type: OBSERVATIONAL
Last Updated: 2024-12-10
Start Date: 2017-12-15
Completion: 2019-08-01
Conditions
Acute Infection Sepsis
No Results Yet
NCT03455608 | COMPLETED | NA
952 Participants

PRO-ACTIVE: Prophylactic Swallow Intervention for Patients Receiving Radiotherapy for Head and Neck Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2018-09-27
Completion: 2024-11-15
Conditions
Dysphagia
Interventions
BEHAVIORAL
No Results Yet
NCT03370718 | COMPLETED | PHASE2
18 Participants

Cabozantinib in Treating Patients With Locally Advanced or Metastatic Unresectable Adrenocortical Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2018-02-26
Completion: 2024-01-12
Conditions
Metastatic Carcinoma in the Adrenal Cortex Stage III Adrenal Cortex Carcinoma AJCC v8 Stage IV Adrenal Cortex Carcinoma AJCC v8 Unresectable Adrenal Cortex Carcinoma
Interventions
DRUG OTHER
NCT03329092 | COMPLETED | PHASE3
422 Participants

A Study to Determine the Efficacy, Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI) ± Metronidazole (MTZ) Versus Meropenem (MER) ± Colistin (COL) for the Treatment of Serious Infections Due to Gram Negative Bacteria.

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2018-04-05
Completion: 2023-02-23
Conditions
Complicated Intra-abdominal Infection Hosptial Acquired Pneumonia Ventilator Associated Pneumonia
Interventions
DRUG
NCT03316638 | TERMINATED | PHASE1/PHASE2
316 Participants

A Study of a New Investigational Medicinal Product to Treat Patients with Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2017-11-24
Completion: 2021-10-30
Conditions
Advanced or Metastatic Solid Tumors
Interventions
DRUG
No Results Yet
NCT03214354 | RECRUITING | PHASE2
12 Participants

Nonmyeloablative Stem Cell Transplant in Children with Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2017-07-05
Completion: 2028-07-31
Conditions
Sickle Cell Disease Stem Cell Transplant Complications Red Blood Cell Disorder Pure Red Cell Aplasia
Interventions
DRUG RADIATION
No Results Yet
NCT03164694 | WITHDRAWN | PHASE2
0 Participants

APatinib Plus Chemotherapy vErsus Chemotherapy As First-line Treatment for Advanced NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2017-05-20
Completion: 2025-05-20
Conditions
Lung Cancer
Interventions
DRUG
No Results Yet
NCT03151733 | COMPLETED | NA
200 Participants

Single Incision Laparoscopic Colorectal Surgery

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2017-06-28
Completion: 2019-06-29
Conditions
Laparoscopic Colorectal Surgery
Interventions
PROCEDURE
No Results Yet
NCT03066063 | COMPLETED
92 Participants

A New Approach to Vision Therapy Based on Naturalistic 3-D Computer Gaming

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2019-05-07
Completion: 2022-02-28
Conditions
Amblyopia Ocular Motility Disorders
Interventions
DEVICE BEHAVIORAL
NCT03047577 | TERMINATED | NA
237 Participants

Brief Intervention for ICU Patients with Alcohol Use Disorders

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2017-03-30
Completion: 2022-07-12
Conditions
Alcohol Use Disorder Critically Ill
Interventions
BEHAVIORAL
No Results Yet
NCT03030417 | COMPLETED | PHASE1
36 Participants

Indenoisoquinoline LMP744 in Adults With Relapsed Solid Tumors and Lymphomas

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2017-02-27
Completion: 2023-10-02
Conditions
Solid Tumors Lymphoma
Interventions
DRUG OTHER
NCT02978378 | TERMINATED
2 Participants

Renal Biomarkers to Predict Recovery Following Venoarterial Extracorporeal Membrane Oxygenation

Study Type: OBSERVATIONAL
Last Updated: 2024-12-10
Start Date: 2017-05-01
Completion: 2018-03-23
Conditions
Acute Kidney Injury
Interventions
OTHER
No Results Yet
NCT02942277 | COMPLETED | PHASE1
301 Participants

Safety and Immunogenicity of Pfs25M-EPA/AS01 and Pfs230D1M-EPA/AS01 Vaccines, Transmission Blocking Vaccines Against Plasmodium Falciparum, at Full and Fractional Dosing in Adults in Mali

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2016-10-21
Completion: 2020-07-15
Conditions
Malaria
Interventions
BIOLOGICAL OTHER DRUG
NCT02922998 | COMPLETED
64 Participants

CD64 and Antibiotics in Human Sepsis

Study Type: OBSERVATIONAL
Last Updated: 2024-12-10
Start Date: 2016-09-30
Completion: 2019-12-31
Conditions
Antibiotic Resistant Infection Critical Illness SIRS Sepsis
No Results Yet
NCT02878317 | COMPLETED
81 Participants

Skin Autofluorescence as a Risk Marker in People Receiving Dialysis.

Study Type: OBSERVATIONAL
Last Updated: 2024-12-10
Start Date: 2016-09-21
Completion: 2022-03-31
Conditions
Chronic Kidney Disease
NCT02802566 | ACTIVE_NOT_RECRUITING | NA
146 Participants

BMI-based Vitamins in Obese Pregnant Women

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2014-12-31
Completion: 2017-09-30
Conditions
Obesity
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT02797080 | COMPLETED | PHASE3
38 Participants

Long-Term Safety Extension Study of ACTIMMUNE® (Interferon γ-1b) in Children and Young Adults With Friedreich's Ataxia

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2016-06-28
Completion: 2017-03-31
Conditions
Friedreich's Ataxia
Interventions
DRUG
NCT02784171 | COMPLETED | PHASE2/PHASE3
520 Participants

Pembrolizumab in Patients With Advanced Malignant Pleural Mesothelioma

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2016-11-11
Completion: 2024-10-11
Conditions
Mesothelioma
Interventions
DRUG
NCT02588404 | WITHDRAWN
0 Participants

The Predictive Value of TMPRSS2-ERG Fusion in High Risk Prostate Cancer Patient

Study Type: OBSERVATIONAL
Last Updated: 2024-12-10
Start Date: 2015-12-31
Completion: 2030-01-31
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT02588261 | TERMINATED | PHASE3
530 Participants

A Study of ASP8273 vs. Erlotinib or Gefitinib in First-line Treatment of Patients With Stage IIIB/IV Non-small Cell Lung Cancer Tumors With EGFR Activating Mutations

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2016-02-11
Completion: 2017-12-21
Conditions
Non-small Cell Lung Cancer (NSCLC)
Interventions
DRUG
NCT02506192 | COMPLETED | PHASE2
83 Participants

Gulf War Illness Inflammation Reduction Trial

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2015-07-31
Completion: 2023-10-19
Conditions
Chronic Inflammation Chronic Pain Fatigue Cognitive Impairment
Interventions
DRUG
NCT02428764 | WITHDRAWN | PHASE2
0 Participants

Neoadjuvant Nimotuzumab Plus Gemcitabine and Carboplatin in Unresectable Stage III Squamous Cell Lung Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2015-04-01
Completion: 2025-10-01
Conditions
Lung Cancer
Interventions
DRUG PROCEDURE
No Results Yet
NCT02362464 | COMPLETED | PHASE2
14 Participants

Long-Term TARP Vaccination Using a Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Previously Vaccinated Men on NCI 09-C-0139

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2015-05-12
Completion: 2022-03-25
Conditions
Prostatic Neoplasms Neoplasms of Prostate Prostate Cancer Cancer Of Prostate Stage D0 Prostate Cancer
Interventions
BIOLOGICAL
NCT02347839 | WITHDRAWN | PHASE2
0 Participants

NEoadjuvant Gefitinib fOllowed by Surgery and gefiTinib In unresectAble sTage III NSCLC With EGFR Mutations.

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2016-01-01
Completion: 2025-01-01
Conditions
Lung Cancer
Interventions
PROCEDURE
No Results Yet
NCT02218606 | COMPLETED | PHASE2
81 Participants

Multicenter Trial of Abiraterone Acetate With or Without Cabazitaxel in Treatment of Metastatic Castration Resistant Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2014-08-31
Completion: 2023-10-13
Conditions
Prostate Cancer
Interventions
DRUG
NCT02196155 | RECRUITING | NA
54 Participants

Botulinum Toxin A Versus Steroids for the Treatment of Chronic Plantar Fasciitis

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2016-07-31
Completion: 2026-12-31
Conditions
Plantar Fasciitis
Interventions
DRUG
No Results Yet
NCT02167802 | COMPLETED
524 Participants

Construction and Validation of a Tool for Automatic Identification of Care Pathways At Risk of Sub-optimality in the Management of Severe Infections in Children (DIABACT IV)

Study Type: OBSERVATIONAL
Last Updated: 2024-12-10
Start Date: 2015-03-20
Completion: 2020-03-07
Conditions
Severe Infection
No Results Yet
NCT02023996 | COMPLETED | NA
42 Participants

PET Imaging With 89Zr-DFO-Trastuzumab in Esophagogastric Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2013-12-31
Completion: 2023-06-27
Conditions
Esophagogastric Cancer
Interventions
RADIATION DEVICE
NCT01650194 | COMPLETED | PHASE2
60 Participants

A Study to Determine Safety and Tolerability of Enzalutamide (MDV3100) in Combination With Abiraterone Acetate in Bone Metastatic Castration-Resistant Prostate Cancer Patients

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2012-07-09
Completion: 2018-01-04
Conditions
Metastatic Castration-Resistant Prostate Cancer
Interventions
DRUG
NCT01602029 | COMPLETED | PHASE2
303 Participants

Randomized Double Blind Placebo Control Study in Patients with Schizophrenia

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2010-08-31
Completion: 2013-06-30
Conditions
Schizophrenia Schizoaffective Disorder Psychosis Not Otherwise Specified Schizophreniform Disorder
Interventions
DRUG
No Results Yet
NCT01350180 | WITHDRAWN
0 Participants

Assessing DNA Changes in High Risk Prostate Cancer to Determine Prognosis

Study Type: OBSERVATIONAL
Last Updated: 2024-12-10
Start Date: 2010-09-30
Completion: 2022-11-01
Conditions
Prostate Cancer
No Results Yet
NCT00948116 | RECRUITING
250 Participants

Development of a Biomarker Panel for the Earlier Prediction of Acute Kidney Injury in Patients With Diabetes

Study Type: OBSERVATIONAL
Last Updated: 2024-12-10
Start Date: 2009-06-24
Completion: 2025-12-31
Conditions
Diabetes Mellitus Renal Impairment
No Results Yet
NCT00853866 | COMPLETED | PHASE4
12 Participants

Enhancement of Motor Function with Reboxetine and Transcranial Direct Current Stimulation

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2009-01-31
Completion: 2009-11-30
Conditions
Cerebral Stroke
Interventions
DRUG DEVICE
No Results Yet
NCT00801216 | COMPLETED | PHASE2
40 Participants

High-dose Sequential Chemoimmunotherapy for B-cell Lymphomas With Central Nervous System Involvement

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2007-01-31
Completion: 2013-01-31
Conditions
B-cell Lymphomas
Interventions
DRUG
NCT00413218 | COMPLETED | PHASE3
450 Participants

Isavuconazole (BAL8557) in the Treatment of Candidemia and Other Invasive Candida Infections

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2007-03-08
Completion: 2015-03-03
Conditions
Candidiasis, Invasive Candidemia Mycoses
Interventions
DRUG
NCT00412893 | COMPLETED | PHASE3
527 Participants

Isavuconazole (BAL8557) for Primary Treatment of Invasive Aspergillosis

Study Type: INTERVENTIONAL
Last Updated: 2024-12-10
Start Date: 2007-03-07
Completion: 2013-03-28
Conditions
Aspergillosis Invasive Fungal Infection
Interventions
DRUG
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