Clinical Trials

Showing trials with last updates posted in 2024.

NCT05891561 | RECRUITING | PHASE2
120 Participants

Short-course Trastuzumab, Pertuzumab with Taxanes in the Adjuvant Treatment of Early HER2-positive Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2023-11-01
Completion: 2026-12-31
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
NCT05820230 | COMPLETED
7 Participants

Changes in the Blood-brain Barrier During Maintenance ECT in Formerly Depressed Patients

Study Type: OBSERVATIONAL
Last Updated: 2024-11-27
Start Date: 2023-02-17
Completion: 2024-02-01
Conditions
Depression
No Results Yet
NCT05807763 | ENROLLING_BY_INVITATION | NA
260 Participants

Fundoplication in Laparoscopic PEH Repair Based on FLIP

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2023-02-22
Completion: 2025-02-22
Conditions
Paraesophageal Hernia
Interventions
PROCEDURE
No Results Yet
NCT05794230 | ACTIVE_NOT_RECRUITING | PHASE3
1528 Participants

Study of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Given With Routine Pediatric Vaccines in Healthy Infants and Toddlers in India and the Republic of South Africa

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2023-03-27
Completion: 2025-12-02
Conditions
Meningococcal Immunisation Healthy Volunteers
Interventions
BIOLOGICAL
No Results Yet
NCT05780606 | COMPLETED | NA
2 Participants

Single-cell Transcriptome Identification of UV- and Visible-light-induced Genes in Human Melanocytes in Vivo

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2024-06-13
Completion: 2024-07-11
Conditions
Skin Diseases
Interventions
OTHER
No Results Yet
NCT05751642 | COMPLETED | PHASE1
48 Participants

Safety and Tolerability, Pharmacokinetic, and Pharmacodynamic Study of ALXN1920 in Healthy Participants

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2023-04-19
Completion: 2023-12-04
Conditions
Healthy Participants
Interventions
BIOLOGICAL
No Results Yet
NCT05746975 | COMPLETED
81 Participants

Diabetic Retinopathy Classification: ETDRS 7-fields vs Widefield Imaging (ClarusDR)

Study Type: OBSERVATIONAL
Last Updated: 2024-11-27
Start Date: 2023-04-03
Completion: 2024-11-04
Conditions
Retinopathy, Diabetic
No Results Yet
NCT05736224 | COMPLETED | PHASE1
30 Participants

Assessing a Natural Product Plus Bioadhesive Nanoparticle (BNP) Sunscreen

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2023-05-15
Completion: 2023-09-01
Conditions
Skin Cancer
Interventions
DRUG OTHER
NCT05720702 | COMPLETED | EARLY_PHASE1
31 Participants

A Feasibility Trial of OCM Supplements for the Treatment of NAFLD

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2023-06-30
Completion: 2024-08-23
Conditions
NAFLD
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT05718726 | RECRUITING
300 Participants

Post Splenectomy Infections After Surgery for Peritoneal Malignancies (OPSI)

Study Type: OBSERVATIONAL
Last Updated: 2024-11-27
Start Date: 2021-03-25
Completion: 2026-02-01
Conditions
Infection;Post Surg Procedure Peritoneal Cancer
Interventions
OTHER
No Results Yet
NCT05704010 | RECRUITING | NA
100 Participants

Videocapsule Endoscopy in Lynch Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2018-11-01
Completion: 2025-12-31
Conditions
Lynch Syndrome Lynch Syndrome I Lynch Syndrome II MLH1 Gene Mutation MSH2 Gene Mutation MSH6 Gene Mutation PMS2 Gene Mutation Small Bowel Adenocarcinoma
Interventions
DEVICE
No Results Yet
NCT05674552 | RECRUITING | PHASE2/PHASE3
50 Participants

Exogenous Ketone Esters for Refractory Status Epileptics

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2023-01-10
Completion: 2025-06-30
Conditions
Status Epilepticus
Interventions
DRUG
No Results Yet
NCT05672121 | RECRUITING | PHASE1/PHASE2
42 Participants

Safety and Tolerability of KH631 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2023-02-06
Completion: 2026-12-28
Conditions
Age-Related Macular Degeneration
Interventions
DRUG
No Results Yet
NCT05670847 | RECRUITING | PHASE2/PHASE3
60 Participants

Exogenous Ketone Esters for Drug Resistant Epilepsy

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2023-01-10
Completion: 2025-06-30
Conditions
Drug Resistant Epilepsy
Interventions
DRUG
No Results Yet
NCT05667194 | RECRUITING | PHASE1
45 Participants

Phase 1 Trial of KH617

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2022-12-26
Completion: 2030-09-30
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT05654441 | COMPLETED | PHASE4
104 Participants

Body and Social Behavior

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2022-10-17
Completion: 2023-12-15
Conditions
Psychology, Social Inflammation Defeat, Social Interaction, Social
Interventions
BIOLOGICAL
NCT05653726 | RECRUITING | NA
390 Participants

Multidimensional Impact of Telemonitoring in Heart Failure (IMPACT-HF)

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2023-11-29
Completion: 2025-06-15
Conditions
Heart Failure
Interventions
OTHER
No Results Yet
NCT05652283 | ACTIVE_NOT_RECRUITING | PHASE2
37 Participants

Pamiparib Combined With Surufatinib for the Neoadjuvant Treatment of Unresectable Ovarian Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2022-11-06
Completion: 2024-05-31
Conditions
Ovarian Cancer
Interventions
DRUG
No Results Yet
NCT05650528 | COMPLETED | PHASE1
78 Participants

QG101-23-0 Capsules SAD and MAD Study in Healthy Subjects

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2023-03-21
Completion: 2024-01-24
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT05630092 | COMPLETED | NA
93 Participants

Comparing 6-Minute Walk Tests for Ambulatory Oxygen Assessment

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2023-01-01
Completion: 2024-02-23
Conditions
Respiratory Disease
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05625503 | COMPLETED | EARLY_PHASE1
55 Participants

Dilution of Verapamil During Intraarterial Administration

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2022-12-13
Completion: 2023-12-01
Conditions
Vasospasm;Peripheral Burning Pain
Interventions
DRUG
No Results Yet
NCT05621460 | RECRUITING | NA
25 Participants

The Effect of Water Carbonation on Orthostatic Tolerance

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2023-09-01
Completion: 2026-04-30
Conditions
Orthostatic Hypotension Syncope Vasovagal Syncope
Interventions
OTHER
No Results Yet
NCT05617209 | COMPLETED
20 Participants

In Vitro Correction of Thrombin Generation by Concizumab (Anti-TFPI) for Severe Hemophilia Patients

Study Type: OBSERVATIONAL
Last Updated: 2024-11-27
Start Date: 2021-09-07
Completion: 2023-01-05
Conditions
Hemophilia
Interventions
OTHER
No Results Yet
NCT05607797 | COMPLETED | NA
1858 Participants

Genetic of Chronic Kidney Disease and Gout in New Caledonia

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2023-03-14
Completion: 2024-04-30
Conditions
Gout Renal Insufficiency, Chronic
Interventions
OTHER
No Results Yet
NCT05588557 | COMPLETED | PHASE1
24 Participants

A Phase I Study to Evaluate the Safety and PK of ND-340 in Healthy Volunteers

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2022-07-08
Completion: 2024-03-19
Conditions
Pain, Postoperative
Interventions
DRUG
No Results Yet
NCT05569473 | COMPLETED | NA
40 Participants

Evaluation of Volume Stable Collagen Matrix in the Regenerative Outcome of Periodontal Intrabony Defects

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2022-10-01
Completion: 2024-01-28
Conditions
Intrabony Periodontal Defect
Interventions
PROCEDURE
No Results Yet
NCT05555771 | RECRUITING | NA
300 Participants

Paediatric Syncope in the Emergency Department

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2022-09-03
Completion: 2026-09-30
Conditions
Syncope, Vasovagal Postural Orthostatic Tachycardia Syndrome Orthostatic Intolerance
Interventions
BEHAVIORAL
No Results Yet
NCT05555758 | COMPLETED | PHASE1
38 Participants

Aom0319 SAD Study in Healthy Subjects

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2022-12-15
Completion: 2023-12-13
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT05548010 | COMPLETED
200 Participants

Venous Thromboembolism (VTE) Knowledge

Study Type: OBSERVATIONAL
Last Updated: 2024-11-27
Start Date: 2022-11-29
Completion: 2023-11-29
Conditions
Thromboembolism
Interventions
OTHER
No Results Yet
NCT05532475 | COMPLETED
40 Participants

Vitreous Level Of Tumor Necrosis Factor Alpha In Patients With Retinal Vein Occlusion

Study Type: OBSERVATIONAL
Last Updated: 2024-11-27
Start Date: 2022-03-12
Completion: 2022-10-20
Conditions
Retinal Vein Occlusion
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05529940 | RECRUITING | PHASE3
609 Participants

NeoFOL-R Trial (Perioperative Versus Adjuvnat FOLFIRINOX in Resectable Pancreatic Cancer)

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2023-04-01
Completion: 2024-12-31
Conditions
Resectable Pancreatic Cancer Neoadjuvant Chemotherapy Effects of Chemotherapy
Interventions
DRUG
No Results Yet
NCT05511519 | TERMINATED | PHASE2
47 Participants

Study of ATI-450 vs Placebo in Patients With Moderate to Severe Psoriatic Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2022-07-12
Completion: 2023-12-06
Conditions
Psoriatic Arthritis
Interventions
DRUG
No Results Yet
NCT05483270 | COMPLETED | NA
845 Participants

Immediate Versus Postponed Freeze-all Embryo Transfer in Hyperresponders

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2022-08-30
Completion: 2024-10-08
Conditions
IVF
Interventions
BIOLOGICAL
No Results Yet
NCT05463367 | ACTIVE_NOT_RECRUITING | PHASE2
60 Participants

Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2021-01-01
Completion: 2025-06-01
Conditions
Opioid Use Opioid Dependence Opioid-use Disorder Narcotic Use Back Pain Back Injuries Chronic Pain Chronic Low-back Pain Pain, Chronic Pain;Back Low;Chronic Pain, Back
Interventions
DRUG
No Results Yet
NCT05446181 | COMPLETED
62 Participants

CLIC1 in Patients Presenting PD

Study Type: OBSERVATIONAL
Last Updated: 2024-11-27
Start Date: 2022-06-27
Completion: 2024-10-30
Conditions
Hip Fractures Hip Disease
Interventions
BEHAVIORAL PROCEDURE
No Results Yet
NCT05432362 | RECRUITING | NA
120 Participants

ESAN II - Energy Sensing in Depression

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2019-02-25
Completion: 2026-01-31
Conditions
Immune System Tolerance Depression Obesity Microbial Colonization Diet, Healthy
Interventions
OTHER
No Results Yet
NCT05419908 | COMPLETED | PHASE2
87 Participants

Trial to Investigate the Effect of ESN364 in Early Postmenopausal Women Suffering From Hot Flashes

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2015-09-21
Completion: 2016-09-21
Conditions
Hot Flashes
Interventions
DRUG
NCT05396157 | ACTIVE_NOT_RECRUITING
813 Participants

Venous Thromboembolism in Hematologic Malignancy and Hematopoietic Cell Transplant Patients: a Retrospective Study

Study Type: OBSERVATIONAL
Last Updated: 2024-11-27
Start Date: 2021-11-01
Completion: 2025-12-31
Conditions
Thrombosis, Venous Bleeding Hemorrhage Venous Thromboembolic Disease Hematologic Malignancy Thrombocytopenia
No Results Yet
NCT05373940 | RECRUITING | NA
730 Participants

Cardioverter DefIbriIlator PlacEMent for priMary Prevention of Sudden cArdiac Death in Patients Older Than 70 Years

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2022-06-29
Completion: 2030-05-31
Conditions
Heart Failure Primary Prevention of Sudden Cardiac Death Implantable Cardioverter Defibrillator
Interventions
DEVICE
No Results Yet
NCT05355402 | COMPLETED | PHASE2
154 Participants

A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe Hypertriglyceridemia

Study Type: INTERVENTIONAL
Last Updated: 2024-11-27
Start Date: 2022-05-09
Completion: 2023-03-22
Conditions
Hypertriglyceridemia Atherosclerotic Cardiovascular Disease Severe Hypertriglyceridemia
Interventions
DRUG
No Results Yet
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