Clinical Trials

Showing trials with last updates posted in 2019.

NCT02335918 | COMPLETED | PHASE1/PHASE2
175 Participants

A Dose Escalation and Cohort Expansion Study of Anti-CD27 (Varlilumab) and Anti-PD-1 (Nivolumab) in Advanced Refractory Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2015-01-31
Completion: 2018-12-12
Conditions
Squamous Cell Carcinoma of the Head and Neck (SCCHN) Ovarian Carcinoma-Enrollment Completed Colorectal Cancer (CRC)-Enrollment Completed Renal Cell Carcinoma (RCC) (Phase ll Only) Glioblastoma (GBM) (Phase ll Only)-Enrollment Completed
Interventions
DRUG
No Results Yet
NCT02317354 | COMPLETED
13 Participants

People s Expectations When Enrolling in a Phase I/II RS1 Ocular Gene Transfer Clinical Trial

Study Type: OBSERVATIONAL
Last Updated: 2019-12-09
Start Date: 2014-12-13
Completion: 2017-11-20
Conditions
Retinoschisis X-Linked
No Results Yet
NCT02265952 | COMPLETED | PHASE2
9 Participants

Study of REGN1500 in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2015-02-04
Completion: 2016-11-21
Conditions
Homozygous Familial Hypercholesterolemia
Interventions
DRUG
NCT02181062 | COMPLETED | NA
240 Participants

Culturally Tailoring a Stroke Intervention in Community Senior Centers

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2014-10-31
Completion: 2016-08-31
Conditions
Hypertension Stroke Sedentary Lifestyle Aged Minority Groups
Interventions
BEHAVIORAL
No Results Yet
NCT02168660 | COMPLETED | PHASE2
109 Participants

Correction of Vitamin D Levels and Its Effect on Insulin Resistance and Weight Gain in Obese Youth

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2011-03-31
Completion: 2013-09-30
Conditions
Obesity Insulin Resistance Vitamin D Deficiency
Interventions
DRUG
NCT02144155 | TERMINATED | NA
14 Participants

Open-label Study of the Efficacy of Intranasal Oxytocin in Schizophrenia

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2012-03-31
Completion: 2014-12-31
Conditions
Schizophrenia
Interventions
DRUG
NCT02085447 | COMPLETED | NA
30 Participants

A Concierge Model of CAE Plus LAI in Individuals With Schizophrenia at Risk for Treatment Non-adherence and Homelessness

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2014-05-31
Completion: 2016-11-30
Conditions
Psychotic Disorders Schizophrenia Schizoaffective Disorder Medication Adherence Medication Non-Adherence
Interventions
BEHAVIORAL
NCT02064049 | COMPLETED | PHASE4
3692 Participants

Surveillance and Treatment of Prisoners With Hepatitis C

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2014-10-31
Completion: 2019-11-30
Conditions
Hepatitis C
Interventions
DRUG
No Results Yet
NCT02060682 | COMPLETED
60 Participants

Post-Market Registry of the ACIST CPM System and Navvus Catheter in Clinical Practice

Study Type: OBSERVATIONAL
Last Updated: 2019-12-09
Start Date: 2014-02-28
Completion: 2014-07-31
Conditions
Coronary Artery Disease
Interventions
DEVICE
No Results Yet
NCT02038920 | COMPLETED | PHASE3
157 Participants

Phase III Study of MLN0002 (300 mg) in Treatment of Crohn's Disease

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2014-01-28
Completion: 2019-01-25
Conditions
Crohn's Disease
Interventions
DRUG
NCT02025816 | COMPLETED
35 Participants

RNAseq Analysis of Microbial Gene Expression in Necrotizing Soft Tissue Infections

Study Type: OBSERVATIONAL
Last Updated: 2019-12-09
Start Date: 2013-12-31
Completion: 2017-09-30
Conditions
Necrotizing Soft Tissue Infections
No Results Yet
NCT01885052 | COMPLETED | PHASE2
4432 Participants

Evaluation of National Cancer Institute Young Adult Stop-Smoking Program

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2013-06-12
Completion: 2014-10-12
Conditions
Smoking Smoking Cessation Cigarette Smoking Tobacco, Smoking
Interventions
BEHAVIORAL
No Results Yet
NCT01878019 | COMPLETED
92 Participants

Brain Response to Pain Control in People With Chronic Pain

Study Type: OBSERVATIONAL
Last Updated: 2019-12-09
Start Date: 2013-05-28
Completion: 2016-09-08
Conditions
Pain
No Results Yet
NCT01844687 | COMPLETED | PHASE2
50 Participants

Laboratory Study of Cannabidiol on the Effects of Smoked Marijuana

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2013-05-31
Completion: 2014-10-31
Conditions
Smoking, Marijuana
Interventions
DRUG
NCT01816048 | TERMINATED | PHASE2
8 Participants

NaF Positron Emission Tomography/Computed Tomography (PET/CT)Imaging to Assess Treatment Responsiveness to TAK-700 in Patients With Castrate Resistant Prostate Cancer (CRPC) With Bone Metastasis

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2013-05-31
Completion: 2015-12-31
Conditions
Prostatic Neoplasms Prostate Cancer
Interventions
DRUG RADIATION PROCEDURE
NCT01797874 | COMPLETED | PHASE2
97 Participants

Pazopanib Maintenance for SCLC

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2013-06-30
Completion: 2017-02-28
Conditions
SCLC
Interventions
DRUG
No Results Yet
NCT01796379 | COMPLETED | NA
80 Participants

High Intensity Training in de Novo Heart Transplant Recipients in Scandinavia

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2013-02-28
Completion: 2019-12-31
Conditions
Heart Transplant Recipients Physical Fitness
Interventions
BEHAVIORAL
No Results Yet
NCT01778582 | COMPLETED
200 Participants

Perspective-taking, and Examining the Clinical Trial Informed Consent Process

Study Type: OBSERVATIONAL
Last Updated: 2019-12-09
Start Date: 2012-11-15
Completion: 2013-10-01
Conditions
Emotions Informed Consent
No Results Yet
NCT01715129 | COMPLETED | PHASE3
126 Participants

Induction and Maintenance of Castration After Subcutaneous Injections of Triptorelin Pamoate in Patients With Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2013-01-31
Completion: 2013-10-31
Conditions
Prostate Cancer
Interventions
DRUG
NCT01667549 | COMPLETED | NA
97 Participants

Sensitive Periods in Human Flavor Learning

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2012-08-31
Completion: 2015-07-31
Conditions
Development
Interventions
OTHER
NCT01621607 | COMPLETED
89 Participants

Individual Differences in Reward and Impulse Control

Study Type: OBSERVATIONAL
Last Updated: 2019-12-09
Start Date: 2012-06-08
Conditions
Drug Addiction Vulnerability to Substance Addiction
No Results Yet
NCT01579513 | COMPLETED | NA
190 Participants

Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2012-06-30
Completion: 2018-05-25
Conditions
Congenital Heart Disease Disorder of Fetus or Newborn
Interventions
DRUG
NCT01503242 | COMPLETED | PHASE1
15 Participants

90 Y-BC8-DOTA Monoclonal Antibody, Fludarabine Phosphate, and Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2012-01-09
Completion: 2017-06-06
Conditions
Plasma Cell Myeloma Refractory Plasma Cell Myeloma
Interventions
PROCEDURE DRUG RADIATION
No Results Yet
NCT01488526 | COMPLETED | PHASE4
200 Participants

Tenofovir in Late Pregnancy to Prevent Vertical Transmission of Hepatitis B Virus

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2012-03-01
Completion: 2014-04-28
Conditions
Hepatitis B Infection Chronic Infection Viremia
Interventions
DRUG
No Results Yet
NCT01468857 | COMPLETED
50 Participants

Physical and Emotional Health of Caregivers for People Who Have Had Stem Cell Transplants

Study Type: OBSERVATIONAL
Last Updated: 2019-12-09
Start Date: 2011-09-26
Conditions
Stress Family Caregivers
No Results Yet
NCT01468805 | WITHDRAWN | NA
0 Participants

Childhood Asthma Reduction Study

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2011-09-04
Completion: 2013-11-15
Conditions
Asthma
Interventions
PROCEDURE
No Results Yet
NCT01444911 | TERMINATED | PHASE2
29 Participants

Evaluation of The Vaginal Renewalโ„ข Program in Gynecologic Cancer Patients Experiencing Sexual Dysfunction

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2011-08-31
Completion: 2013-05-31
Conditions
Sexual Dysfunction, Physiological
Interventions
DEVICE
NCT01421888 | TERMINATED
4 Participants

The NIH UNI Study: Urea Cycle Disorders, Nutrition and Immunity

Study Type: OBSERVATIONAL
Last Updated: 2019-12-09
Start Date: 2011-08-08
Conditions
Argininosuccinic Aciduria Carbamoyl-Phosphate Synthase I Deficiency Citrullinemia Ornithine Carbamoyltransferase Deficiency Hyperargininemia N-Acetylglutamate Synthase Deficiency
No Results Yet
NCT01328600 | COMPLETED
144 Participants

Marinobufagenin as a Target for DIGIBIND in Preeclampsia

Study Type: OBSERVATIONAL
Last Updated: 2019-12-09
Start Date: 2006-08-16
Conditions
Preeclampsia
No Results Yet
NCT01312350 | COMPLETED | PHASE2
40 Participants

Neoadjuvant Chemotherapy for Locally Advanced Squamous Cell Cancer of the Head and Neck (SCCHN)

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2010-11-30
Completion: 2016-03-31
Conditions
Hypopharyngeal Cancer
Interventions
DRUG
No Results Yet
NCT01251575 | COMPLETED | PHASE2
77 Participants

Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Blood Cancer Undergoing Donor Peripheral Blood Stem Cell Transplant

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2010-12-01
Completion: 2018-11-23
Conditions
Adult Acute Lymphoblastic Leukemia Adult Acute Myeloid Leukemia Adult Diffuse Large B-Cell Lymphoma Adult Myelodysplastic Syndrome Adult Non-Hodgkin Lymphoma Aggressive Non-Hodgkin Lymphoma Childhood Acute Lymphoblastic Leukemia Childhood Acute Myeloid Leukemia Childhood Diffuse Large B-Cell Lymphoma Childhood Myelodysplastic Syndrome Childhood Non-Hodgkin Lymphoma Chronic Lymphocytic Leukemia Chronic Lymphocytic Leukemia in Remission Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive Hematopoietic and Lymphoid Cell Neoplasm Mantle Cell Lymphoma Plasma Cell Myeloma Prolymphocytic Leukemia Recurrent Chronic Lymphocytic Leukemia Refractory Chronic Lymphocytic Leukemia T-Cell Prolymphocytic Leukemia Waldenstrom Macroglobulinemia Recurrent Diffuse Large B-Cell Lymphoma Recurrent Hodgkin Lymphoma
Interventions
PROCEDURE DRUG OTHER RADIATION
NCT01220115 | COMPLETED
498 Participants

A 3-year, Prospective, Non-interventional, Multicenter Registry in Sickle Cell Disease (SCD) Patients

Study Type: OBSERVATIONAL
Last Updated: 2019-12-09
Start Date: 2010-01-31
Completion: 2014-09-30
Conditions
Sickle Cell Disease
No Results Yet
NCT01148004 | COMPLETED | PHASE1
25 Participants

The Influence of Ritonavir, Alone and in Combination With Lopinavir, on Fenofibric Acid Pharmacokinetics in Healthy Volunteers

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2010-05-13
Completion: 2013-07-29
Conditions
HIV Fenofibrate Protease Inhibitors Hypertriglyceridemia Glucuronosyltransferase
Interventions
DRUG
No Results Yet
NCT01128387 | TERMINATED | PHASE1/PHASE2
11 Participants

Trial of Panitumumab/Cisplatin/Fluorouracil Combined With Radiation in Esophageal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2010-05-31
Completion: 2016-10-31
Conditions
Cancer
Interventions
DRUG
NCT01083641 | TERMINATED | PHASE2
17 Participants

Estrogen for Triple Negative Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2010-01-31
Completion: 2013-06-30
Conditions
Female Breast Cancer
Interventions
DRUG
NCT01071590 | COMPLETED
45 Participants

The Influence of Sensory Stimuli on Gait Imagery in Patients With Freezing of Gait

Study Type: OBSERVATIONAL
Last Updated: 2019-12-09
Start Date: 2010-02-01
Conditions
Parkinson Disease
No Results Yet
NCT01035996 | COMPLETED
159 Participants

Dopamine Function and Reward Processing In Schizophrenia

Study Type: OBSERVATIONAL
Last Updated: 2019-12-09
Start Date: 2005-03-08
Conditions
Schizophrenia
No Results Yet
NCT00994071 | COMPLETED | PHASE1
9 Participants

A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2009-09-22
Conditions
Medulloblastoma Pontine Glioma Ependymoma Astrocytoma PNET
Interventions
DRUG
No Results Yet
NCT00985946 | TERMINATED | PHASE2
15 Participants

Study of Panobinostat in Patients With Neuroendocrine Tumors

Study Type: INTERVENTIONAL
Last Updated: 2019-12-09
Start Date: 2010-05-31
Completion: 2015-04-30
Conditions
Neuroendocrine Tumors
Interventions
DRUG
NCT00891956 | COMPLETED
426 Participants

The Role of Family Functioning in Adaptation to Being a Caregiver of an Individual With Rett Syndrome

Study Type: OBSERVATIONAL
Last Updated: 2019-12-09
Start Date: 2009-04-24
Conditions
Rett Syndrome
No Results Yet
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