Effect of Indoor Air Quality Improvement on Health in Patients With Interstitial Lung Disease

NCT ID: NCT07344987

Last Updated: 2026-01-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2026-03-31

Study Completion Date

2027-06-30

Brief Summary

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Air pollution threatens the respiratory health of patients with interstitial lung disease (ILD). High-efficiency air purifiers, featuring easy operation and excellent particulate matter removal efficiency, have been shown in previous studies to potentially delay lung function deterioration and reduce acute exacerbation risk in respiratory disease patients. This randomized crossover study employs air purifiers to filter indoor gaseous pollutants, allergens, and other contaminants, aiming to alleviate respiratory irritation, improve daily life comfort, and enhance overall health status in ILD patients.

Detailed Description

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Conditions

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ILD

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

Study Groups

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Purifier (without Filter) Arm

Group Type SHAM_COMPARATOR

Purifier (without Filter) Arm

Intervention Type BEHAVIORAL

Place an air purifier without a filter in the home.

Air Purifier (with Filter) Arm

Group Type EXPERIMENTAL

Air Purifier (with Filter) Arm

Intervention Type BEHAVIORAL

Place an air purifier with high-efficiency filters in the home, and turn it on for at least 18 hours every day.

Interventions

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Air Purifier (with Filter) Arm

Place an air purifier with high-efficiency filters in the home, and turn it on for at least 18 hours every day.

Intervention Type BEHAVIORAL

Purifier (without Filter) Arm

Place an air purifier without a filter in the home.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Patients diagnosed with interstitial lung disease (ILD).
* Stable disease status, defined as no hospitalization due to acute exacerbation within the past month.

Exclusion Criteria

* Patients with complications of severe organ failure (including heart, liver, or kidney failure), malignant tumors, or mental disorders.
* A history of respiratory tract infection within the past two weeks.
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Peking Union Medical College

OTHER

Sponsor Role lead

Responsible Party

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Hongbing Xu

Prof.

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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CAMS-PUMC-IRM-IAQ-ILD-2025

Identifier Type: -

Identifier Source: org_study_id

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