Pulmonary Rehabilitation in Interstitial Lung Diseases

NCT ID: NCT00882817

Last Updated: 2013-08-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-04-30

Study Completion Date

2011-11-30

Brief Summary

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Treatment in interstitial lung diseases (ILD) is frequently ineffective. Pulmonary rehabilitation (PR) is an excellent therapeutic option in another chronic lung diseases such as chronic obstructive pulmonary disease (COPD). This prospective randomized controlled study aims to evaluate the short and long-term effects of PR in patients with ILD. For this purpose, 60 ILD patients will be randomly assigned to a PR or a control group.

The investigators hypothesize that PR will improve exercise capacity, increase muscle force, reduce dyspnea and improve quality of life and daily life activities in ILD patients.

Detailed Description

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Conditions

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Interstitial Lung Disease

Keywords

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ILD

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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1

Pulmonary Rehabilitation

Group Type ACTIVE_COMPARATOR

Pulmonary Rehabilitation

Intervention Type OTHER

The intervention group will perform a 6 month pulmonary rehabilitation program which consists of training, patient education, nutrition counseling and psychosocial support. They will be evaluated with some tests for the study.

2

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Pulmonary Rehabilitation

The intervention group will perform a 6 month pulmonary rehabilitation program which consists of training, patient education, nutrition counseling and psychosocial support. They will be evaluated with some tests for the study.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of interstitial lung disease according to internationally established criteria
* Dyspnea on exertion
* Stable medical therapy
* Stable clinical condition at inclusion, with no infection or exacerbation in the previous 4 weeks

Exclusion Criteria

* Co-morbidities that do not allow exercise training (unstable angina, recent myocardial infarction or cerebrovascular accident, active cancer, severe orthopedic disorders).
* Life expectancy below 3 months
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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KU Leuven

OTHER

Sponsor Role lead

Responsible Party

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Marc Decramer

Prof. Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Silvia Pérez-Bogerd, MD

Role: PRINCIPAL_INVESTIGATOR

KU Leuven

Wim Janssens, MD PhD

Role: PRINCIPAL_INVESTIGATOR

KU Leuven

Wim Wuyts, MD PhD

Role: PRINCIPAL_INVESTIGATOR

KU Leuven

Locations

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Katholieke Universiteit Leuven

Leuven, Flanders, Belgium

Site Status

Countries

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Belgium

References

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Perez-Bogerd S, Wuyts W, Barbier V, Demeyer H, Van Muylem A, Janssens W, Troosters T. Short and long-term effects of pulmonary rehabilitation in interstitial lung diseases: a randomised controlled trial. Respir Res. 2018 Sep 20;19(1):182. doi: 10.1186/s12931-018-0884-y.

Reference Type DERIVED
PMID: 30236104 (View on PubMed)

Other Identifiers

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S1490

Identifier Type: -

Identifier Source: secondary_id

B32220095560

Identifier Type: -

Identifier Source: org_study_id