Quality of Life and the Influence of Stress on the Postoperative Course of Patients After Device Implantation

NCT ID: NCT07343466

Last Updated: 2026-01-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-02-04

Study Completion Date

2029-07-15

Brief Summary

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The project "Investigating Quality of Life and the Influence of Stress on the Postoperative Course of Patients After Device Implantation" aims to investigate the relationship between stress and the postoperative healing process of patients who have had a medical device implanted. These devices include pacemakers for the treatment of bradycardia, implantable cardioverter-defibrillators (ICDs) for the treatment of tachycardia in primary and secondary prevention, and cardiac resynchronization therapy (CRT) devices and event recorders. The study will analyze the influence of stress on the postoperative course, potential complications, and overall quality of life. A combination of medical examinations and surveys will be used to analyze how psychological stress influences the physical healing process and which measures can contribute to improving quality of life and treatment success. The surgical procedure for implanting devices is not part of the study; this is an observational study.

Detailed Description

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Conditions

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Quality of Life (QOL) and Impact of Stress

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with indication for device implantation (pacemaker, ICD, CRT, event recorder)

Patients with cardiac diseases, that makes a device implantation (pacemaker, ICD, CRT, event recorder) necessary, including primary and secondary indication for an ICD.

Survey using a questionnaire.

Intervention Type OTHER

survery over 36 months with comparison of the questionnares with risk-factors, blood-samples and physical fitness of the patient

Interventions

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Survey using a questionnaire.

survery over 36 months with comparison of the questionnares with risk-factors, blood-samples and physical fitness of the patient

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients of legal capacity with an indication for device implantation (pacemaker, ICD, CRT, event recorder) who present at the Department of Cardiology and Angiology at the University Hospital Essen and consent to participate in the study will be included.

Exclusion Criteria

* none
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Essen

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Tienush Rassaf, Univ.-Prof. Dr. med.

Role: STUDY_CHAIR

Universitätsklinikum Essen

Julia Lortz, Prof. Dr. med.

Role: STUDY_DIRECTOR

Universitätsklinikum Essen

Muhammed Kurt, Dr. med.

Role: STUDY_DIRECTOR

Universitätsklinikum Essen

Locations

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Universitätsklinikum Essen, Klinik für Kardiologie und Angiologie

Essen, North Rhine-Westphalia, Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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Muhammed Kurt, Dr. med.

Role: CONTACT

+49 201-723 86255

Julia Lortz, Prof. Dr. med.

Role: CONTACT

+49 201-723 84995

Facility Contacts

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Julia Lortz, Prof. Dr. med.

Role: primary

+49 201-723 84995

Muhammed Kurt, Dr. med.

Role: backup

+49 201-723 86255

References

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Golbidi S, Frisbee JC, Laher I. Chronic stress impacts the cardiovascular system: animal models and clinical outcomes. Am J Physiol Heart Circ Physiol. 2015 Jun 15;308(12):H1476-98. doi: 10.1152/ajpheart.00859.2014. Epub 2015 Apr 17.

Reference Type BACKGROUND
PMID: 25888514 (View on PubMed)

Pedersen SS, Wehberg S, Nielsen JC, Riahi S, Larroude C, Philbert BT, Johansen JB; DEFIB-WOMEN Investigators. Patients with an implantable cardioverter defibrillator at risk of poorer psychological health during 24 months of follow-up (results from the Danish national DEFIB-WOMEN study). Gen Hosp Psychiatry. 2023 Jan-Feb;80:54-61. doi: 10.1016/j.genhosppsych.2022.12.006. Epub 2023 Jan 3.

Reference Type BACKGROUND
PMID: 36638700 (View on PubMed)

Kim J, Park JK, Choi J, Kim SH, On YK, Shin MS, Choi N, Heo S. Changes in the Physical Function and Psychological Distress from Pre-Implant to 1, 6, and 12 Months Post-Implant in Patients Undergoing Implantable Cardioverter Defibrillator Therapy. J Clin Med. 2020 Jan 22;9(2):307. doi: 10.3390/jcm9020307.

Reference Type BACKGROUND
PMID: 31979074 (View on PubMed)

van Barreveld M, Verstraelen TE, van Dessel PFHM, Boersma LVA, Delnoy PPHM, Tuinenburg AE, Theuns DAMJ, van der Voort PH, Kimman GJ, Buskens E, Zwinderman AH, Wilde AAM, Dijkgraaf MGW; DO-IT Registry Investigators. Dutch Outcome in Implantable Cardioverter-Defibrillator Therapy: Implantable Cardioverter-Defibrillator-Related Complications in a Contemporary Primary Prevention Cohort. J Am Heart Assoc. 2021 Apr 6;10(7):e018063. doi: 10.1161/JAHA.120.018063. Epub 2021 Mar 31.

Reference Type BACKGROUND
PMID: 33787324 (View on PubMed)

Miller JL, Thylen I, Elayi SC, Etaee F, Fleming S, Czarapata MM, Lennie TA, Moser DK. Multi-morbidity burden, psychological distress, and quality of life in implantable cardioverter defibrillator recipients: Results from a nationwide study. J Psychosom Res. 2019 May;120:39-45. doi: 10.1016/j.jpsychores.2019.03.006. Epub 2019 Mar 5.

Reference Type BACKGROUND
PMID: 30929706 (View on PubMed)

Lampert R. Managing with pacemakers and implantable cardioverter defibrillators. Circulation. 2013 Oct 1;128(14):1576-85. doi: 10.1161/CIRCULATIONAHA.113.001555. No abstract available.

Reference Type BACKGROUND
PMID: 24081953 (View on PubMed)

Linde C. Quality-of-life in pacemaker and implantable cardioverter defibrillator recipients. Pacing Clin Electrophysiol. 2000 Jun;23(6):931-3. doi: 10.1111/j.1540-8159.2000.tb00876.x. No abstract available.

Reference Type BACKGROUND
PMID: 10879374 (View on PubMed)

Su SF, Wu MS. Arrhythmia Perception and Quality of Life in Bradyarrhythmia Patients Following Permanent Pacemaker Implantation. Clin Nurs Res. 2021 Feb;30(2):183-192. doi: 10.1177/1054773819880297. Epub 2019 Oct 16.

Reference Type BACKGROUND
PMID: 31617405 (View on PubMed)

Sikora K, Wawryniuk A, Luczyk RJ, Sawicka K, Zwolak A. The Occurrence of Stress, Illness Acceptance and the Quality of Life of Patients after Pacemaker Implantation. Int J Environ Res Public Health. 2022 Oct 29;19(21):14133. doi: 10.3390/ijerph192114133.

Reference Type BACKGROUND
PMID: 36361008 (View on PubMed)

Iliou MC, Blanchard JC, Lamar-Tanguy A, Cristofini P, Ledru F. Cardiac rehabilitation in patients with pacemakers and implantable cardioverter defibrillators. Monaldi Arch Chest Dis. 2016 Oct 14;86(1-2):756. doi: 10.4081/monaldi.2016.756.

Reference Type BACKGROUND
PMID: 27748467 (View on PubMed)

Other Identifiers

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24-12310-BO

Identifier Type: -

Identifier Source: org_study_id

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