The Effect of Education on Quality of Life, Adherence to Immunosuppressive Therapy and Symptom Control in Organ Transplant Patients
NCT ID: NCT07288918
Last Updated: 2025-12-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
108 participants
INTERVENTIONAL
2025-12-10
2026-08-30
Brief Summary
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Individuals who undergo transplantation and their families often perceive transplantation as a rebirth. However, 30% to 40% of patients report no better health-related quality of life after kidney transplantation compared to dialysis. This is attributed to frequent checkups and monitoring, new medications and their strict dosing schedules, and the unexpected discomfort of potential side effects.
Even after the psychological challenges of waiting and the joy of a successful transplant, transplant recipients take on new responsibilities. Problems such as accepting transplantation risks, acute and chronic organ rejection, and adherence to lifelong medication regimens can arise. Persistent side effects of various immunosuppressive agents, adaptation and maintenance of the new organ, and uncertainty about the future due to rejection of transplanted organs and the subsequent re-transplantation process can all lead to physical and psychological distress.
Immunosuppressive therapy represents a lifelong endeavor for transplant recipients. These medication regimens involve complex protocols, not only due to the number of pills required, but also due to blood level monitoring, side effects, and frequent dose adjustments to avoid rejection. Non-adherence to immunosuppressant regimens has been shown to be high in organ transplant patients. Non-adherence rates in this population are reported as high as 65%. The highest immunosuppressant non-adherence rate is found in kidney transplant recipients, with a prevalence of 36-55%, while this rate is 15-40% in liver transplant recipients. Studies have found that 16-36% of graft losses are associated with non-adherence. The ever-growing population of transplant recipients and the limited number of transplant centers, particularly those living farther away, necessitate innovative healthcare delivery models to monitor and improve the use of transplant center resources. With the advent of smartphones and mobile medical devices, mobile health has become a popular way for healthcare professionals to manage patient care. Mobile health can serve as an adjunct method for delivering health education information, sending reminders to patients to take their medications, and implementing online education. In particular, converting paper-based education to video format can significantly increase knowledge on various topics. It is necessary to address the problems and challenges patients face after discharge and the practices that can potentially address these issues. These results suggest that healthcare professionals can do more to provide comprehensive care to patients, promote successful home-based treatment regimens, symptom control, and quality of life.
Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
DOUBLE
Study Groups
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Mobile applications
Mobile application installation
Transplant patients will receive standard discharge training. A mobile application created by the researcher will be installed on transplant patients' phones.
Teaching booklet
Providing teaching booklets
Transplant patients will receive standard discharge training. Transplant patients will be given researcher prepared instructional booklet
Control
Control
Transplant patients will receive standard discharge training
Interventions
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Mobile application installation
Transplant patients will receive standard discharge training. A mobile application created by the researcher will be installed on transplant patients' phones.
Providing teaching booklets
Transplant patients will receive standard discharge training. Transplant patients will be given researcher prepared instructional booklet
Control
Transplant patients will receive standard discharge training
Eligibility Criteria
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Inclusion Criteria
* Having undergone a liver or kidney transplant for the first time,
* Having been discharged at least three months ago,
* Having access to a smartphone and internet and the ability to use them independently,
Exclusion Criteria
* Having hearing or vision problems severe enough to impede communication,
* Requesting to leave during the research period
18 Years
ALL
No
Sponsors
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Ondokuz Mayıs University
OTHER
Responsible Party
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Rıfat GÜRKAN
Principal Investigator
Locations
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Ondokuz Mayis University
Samsun, Samsun, Turkey (Türkiye)
Countries
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Central Contacts
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Rıfat GÜRKAN, Master of Science in Nursing
Role: CONTACT
Phone: +905067154895
Email: [email protected]
Other Identifiers
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OMU-GURKAN-001
Identifier Type: -
Identifier Source: org_study_id