Evaluation of Quality of Life in Patients After Placement of a Modified Double J Ureteral Stent

NCT ID: NCT07275879

Last Updated: 2025-12-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-12-28

Study Completion Date

2026-04-30

Brief Summary

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Double-J (DJ) stents are commonly inserted after ureteroscopy. There are several complications associated with the presence of DJ stent: urinary tract infection, stent encrustation, stent migration, and stent-related symptoms (SRS).

SRS occur in up to 80% of patients and include pain, hematuria, and dysuria, all of which negatively impact the patient's quality of life.

Physicians proposed the distal end of the ureteral stents might involve in SRS by over-simulating the trigone of bladder. The design of the distal end, made with a thinner loop than that of a standard DJ stent, is intended to mitigate SRS and reduce urine reflux.

Detailed Description

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Study Design:

Prospective, randomized, open-label, controlled trial with two parallel arms.

Study Center:

Department of Urology, St. Luke's Clinical Hospital, St. Petersburg, Russia

Study Population:

All patients should not be prestented and should have no ureteral obstruction. 40 patients, divided into four equal groups of 20 people each:

Group I (standard DJ stent):

Group II (modified DJ stent)

Procedure for evaluation:

After surgery ( RIRS, ureteroscopy) reflux is assessed (gravity-filling cystogram). After stenting, the presence of post-stent reflux is assessed.

In the postoperative period, patients complete the USSQ (1st day, 7th day and before stent removal).

Statistics method:

The results are presented as the median and interquartile range (IQR) for continuous variables, and as frequencies (n with percentage %) for categorical variables. Statistical comparisons of all primary and secondary outcome measures between different treatment groups were conducted using the Mann-Whitney U test for continuous data. Meanwhile, categorical variables were analyzed using either Pearson's chi-square (χ²) test or Fisher's exact test, where appropriate. Thenthreshold for statistical significance was established at 5%, implying that a p-value less than 0.05 (p \< 0.05) was considered statistically significant for all tests performed.

Conditions

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Ureteral Double-J Stent Urolithiasis Quality of Life

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Group I (DJ stent)

Non-prestented patients who will insert a standard DJ stent after surgery

Group Type ACTIVE_COMPARATOR

Ureteric stent insertion

Intervention Type PROCEDURE

Ureteric stent insertion is the procedure to place a thin, flexible plastic tube that is temporarily in the ureter to help urine drain. They are placed with cystoscopic and X-ray guidances in an operating room setting

Group II (modified DJ stent)

Non-prestented patients who will insert a modified DJ stent after surgery

Group Type EXPERIMENTAL

Ureteric stent insertion

Intervention Type PROCEDURE

Ureteric stent insertion is the procedure to place a thin, flexible plastic tube that is temporarily in the ureter to help urine drain. They are placed with cystoscopic and X-ray guidances in an operating room setting

Interventions

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Ureteric stent insertion

Ureteric stent insertion is the procedure to place a thin, flexible plastic tube that is temporarily in the ureter to help urine drain. They are placed with cystoscopic and X-ray guidances in an operating room setting

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients aged 18 years and older
* Patients with kidney stones
* Patients with ureteral stones

Exclusion Criteria

* Congenital anomalies of the urinary tract
* Urinary tract infections
* Upper urinary tract obstruction
* Complicated ureteroscopy (e.g., ureteral perforation)
* Pregnancy
* Pre-stented patients
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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St. Luke's Clinical Hospital, Russia

OTHER

Sponsor Role lead

Responsible Party

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Mikheev Yury

Urologist

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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St. Luke's Clinical Hospital

Saint Petersburg, Outside U.S./Canada, Russia

Site Status RECRUITING

Countries

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Russia

Central Contacts

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Dmitriy Sytnik

Role: CONTACT

+7 931 367 78 58

Yury Mikheev

Role: CONTACT

+79315412190

Facility Contacts

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Dmitriy Sytnik

Role: primary

+7 931 367 78 58

Other Identifiers

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21/4

Identifier Type: -

Identifier Source: org_study_id

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