RESOLUTE ONYX Post-Approval Study (Bifurcation Cohort)

NCT ID: NCT03584464

Last Updated: 2023-11-24

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

205 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-05-14

Study Completion Date

2022-09-28

Brief Summary

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To observe the continued performance of the Medtronic Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System in a real-world more-comer population.

To collect data on the safety and efficacy of the Medtronic Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System in bifurcated lesions.

Detailed Description

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Conditions

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Coronary Artery Disease

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Bifurcation Cohort

Subjects receiving stents 2.0 mm - 5.0 mm in diameter will be included in the Bifurcation Cohort.

Group Type OTHER

Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System

Intervention Type DEVICE

Medtronic Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System, sizes 2.0 mm - 5.0 mm

Interventions

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Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System

Medtronic Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System, sizes 2.0 mm - 5.0 mm

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Symptomatic coronary artery disease including subjects with chronic stable angina, silent ischemia, and acute coronary syndromes including non-ST elevation and ST-elevation myocardial infarction
* Subject is an acceptable candidate for treatment with a drug eluting stent in accordance with the applicable guidelines on percutaneous coronary interventions, manufacturer's Instructions for Use, and the Declaration of Helsinki
* Subject requires treatment of a single de novo bifurcated lesion amenable to treatment with Resolute Onyx using the provisional stenting technique

Exclusion Criteria

* Unprotected left main disease
* Subjects with planned PCI of three vessel disease
* Planned two stent technique (main branch and side branch) of a bifurcation
* Subjects with more than one bifurcation lesion
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medtronic Vascular

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Huntsville Hospital

Huntsville, Alabama, United States

Site Status

Scripps Green Hospital

La Jolla, California, United States

Site Status

Riverside Community Hospital

Riverside, California, United States

Site Status

Hartford Hospital

Hartford, Connecticut, United States

Site Status

Morton Plant Hospital

Clearwater, Florida, United States

Site Status

North Florida Regional Medical Center

Gainesville, Florida, United States

Site Status

Tallahassee Memorial Hospital

Tallahassee, Florida, United States

Site Status

WellStar Kennestone Hospital

Marietta, Georgia, United States

Site Status

University of Michigan Health System

Ann Arbor, Michigan, United States

Site Status

Mercy Hospital

Coon Rapids, Minnesota, United States

Site Status

Abbott Northwestern

Minneapolis, Minnesota, United States

Site Status

Nebraska Medical Center

Omaha, Nebraska, United States

Site Status

Desert Springs Hospital

Las Vegas, Nevada, United States

Site Status

St. Josephs Hospital Health Center

East Syracuse, New York, United States

Site Status

North Shore University Hospital

Manhasset, New York, United States

Site Status

NYU Langone Medical Center

New York, New York, United States

Site Status

New York-Presbyterian Hospital/ Columbia University Medical Center

New York, New York, United States

Site Status

Baptist Memorial Hospital-Memphis

Germantown, Tennessee, United States

Site Status

Houston Methodist Hospital

Houston, Texas, United States

Site Status

University of Virginia Medical Center

Charlottesville, Virginia, United States

Site Status

Saint Vincent Hospital

Green Bay, Wisconsin, United States

Site Status

CHU Charleroi

Charleroi, , Belgium

Site Status

Ziekenhuis Oost Limburg

Genk, , Belgium

Site Status

CHU Toulouse - Hôpital Rangueil

Toulouse, , France

Site Status

Stredoslovensky Ustav Srdcovych a Cievnych Chorob a.s

Banská Bystrica, , Slovakia

Site Status

Countries

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United States Belgium France Slovakia

Provided Documents

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Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Other Identifiers

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Ver 4.0 16Feb2018

Identifier Type: -

Identifier Source: org_study_id