The Effect of Prolonged Sugar-Free Chewing Gum Mastication on Self-Reported Fatigue Levels and Changes of Static and Dynamic Surface Electromyography Parameters in Young Individuals With and Without Temporomandibular Joint Disorders.
NCT ID: NCT07273123
Last Updated: 2025-12-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
30 participants
OBSERVATIONAL
2025-12-01
2026-07-30
Brief Summary
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How does self-reported fatigue, measured with a visual analogue scale (VAS), change during sustained chewing? How do static and dynamic surface electromyographic (sEMG) parameters evolve over the same period? Participants with TMD will be compared with healthy controls to determine group differences in perceived fatigue and EMG responses.
All participants will undergo baseline EMG assessment, then chew sugar-free gum continuously for 3 minutes, alternating sides without rest. After each 3-minute interval, static and dynamic EMG recordings will be obtained and participants will rate their fatigue on the VAS. This cycle may be repeated up to six times (maximum 18 minutes). Participants are free to stop chewing at any time if fatigue becomes intolerable.
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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Case group (subjects with TMD)
This group contains subjects with temporomandibular disorders
Mastication of sugar-free chewing gum
The chewing task will last for a maximum of 18 minutes.
Control group (TMD-free subjects)
This group contains healthy subjects without temporomandibular disorders
Mastication of sugar-free chewing gum
The chewing task will last for a maximum of 18 minutes.
Interventions
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Mastication of sugar-free chewing gum
The chewing task will last for a maximum of 18 minutes.
Eligibility Criteria
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Inclusion Criteria
* Chewing-gum users, even occasional
* Good general health
* Good oral health
\- no diagnosed temporomandibular joint disorders
\- diagnosed temporomandibular joint disorders
Exclusion Criteria
* History of neurological disorders
* History of musculoskeletal diseases
* History of facial or cervical injuries
* Presence of cervical pain
* Two or more missing teeth
* Current treatment with fixed or removable orthodontic appliances
* Active periodontal disease
* Presence of cavitated carious lesions
19 Years
35 Years
ALL
Yes
Sponsors
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University of Milan
OTHER
Responsible Party
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Aesha Allam
DDS
Locations
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University of Milan
Milan, Milan, Italy
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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95 /25
Identifier Type: -
Identifier Source: org_study_id
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