Treatment of Tempromandibular Joint Anterior Disc Displacement With Different Materials
NCT ID: NCT06441279
Last Updated: 2024-12-04
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
60 participants
INTERVENTIONAL
2024-04-01
2024-10-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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group 1
30 patients that will have intra-articular injection of 2 ml of Platelet lysate (PL).
intra-articular injection with Platelet lysate (PL).
2 ml of Platelet lysate will be deposited into the superior joint space (SJS) in the affected joint at the entry point slowly
group 2
30 patients that will have intra-articular injection of Hyaluronic Acid.
intra-articular injection with Hyaluronic Acid.
2 ml of Hyaluronic Acid will be deposited into the superior joint space (SJS) in the affected joint at the entry point slowly.
Interventions
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intra-articular injection with Platelet lysate (PL).
2 ml of Platelet lysate will be deposited into the superior joint space (SJS) in the affected joint at the entry point slowly
intra-articular injection with Hyaluronic Acid.
2 ml of Hyaluronic Acid will be deposited into the superior joint space (SJS) in the affected joint at the entry point slowly.
Eligibility Criteria
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Inclusion Criteria
* Patients who will not respond to a previous conservative therapy.
* Patients with pain in temporomandibular joints.
* Patients with normal or limitation in mouth opening.
* Patients with clicking sound.
Exclusion Criteria
* Patients with inflammatory or connective tissue diseases.
* Patients with neurologic disorders.
* Patients with history of bony or fibrous adhesion.
* Patients having gross mechanical restrictions and condylar fractures.
* Patients with psychological problems.
* Patients receiving anti-coagulation treatment, non-steroidal anti-inflammatory drugs within 48 hours pre-operatively, corticosteroid injection at the treatment site within one month or systemic use of corticosteroids within 2 weeks.
18 Years
60 Years
ALL
Yes
Sponsors
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Mansoura University
OTHER
Responsible Party
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Locations
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Heba Elsheikh
Mansoura, Egypt, , Egypt
Countries
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Other Identifiers
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A0103024OS
Identifier Type: -
Identifier Source: org_study_id