Wrist Reduction Intervention: Supracondylar Technique for Radial Nerve Block vs. Hematoma Block (WRIST Block Study)

NCT ID: NCT07268547

Last Updated: 2025-12-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Clinical Phase

PHASE4

Total Enrollment

105 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-12-09

Study Completion Date

2027-12-01

Brief Summary

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The purpose of this study is to compare different types of local anesthesia-a supracondylar radial nerve block, a hematoma block, or a combination of the two-for reducing pain in people with a broken wrist (distal radius fracture). This is being done to find out which method provides better pain relief after the injury and during treatment in the emergency room.

Detailed Description

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This study is testing different ways to provide pain relief before reducing a broken wrist. Participants will receive one of three techniques: (1) a nerve block where a doctor injects lidocaine near the radial nerve under ultrasound guidance; (2) a hematoma block where a doctor injects lidocaine into the area where the bone broke; or (3) both the nerve block and the hematoma block. Patients will be asked how much pain they feel before the numbing, after the numbing, and after the wrist is reduced.

Conditions

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Wrist Fracture

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

The purpose of this study is to compare different types of local anesthesia-a supracondylar radial nerve block, a hematoma block, or a combination of the two-for lowering pain in people with a broken wrist (distal radius fracture). We want to find out which method provides better pain relief after the injury and during treatment in the emergency room. Each of these methods is a different standard procedure for pain control prior to wrist fracture reduction.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Supracondylar radial nerve blocks

Lidocaine injection given near the radial never under ultrasound guidance

Group Type EXPERIMENTAL

Supracondylar radial nerve block

Intervention Type PROCEDURE

Supracondylar radial nerve blocks given at the radial nerve not as the same location of the fracture site, prior to fracture reduction.

Hematoma blocks

Injecting analgesia into the hematoma that forms surrounding the wrist fracture

Group Type EXPERIMENTAL

Hematoma block

Intervention Type PROCEDURE

Injection of analgesia into the hematoma that forms surrounding the wrist fracture.

Combination of supracondylar radial nerve block and hematoma block

Supracondylar radial nerve block given first followed by hematoma block

Group Type EXPERIMENTAL

Combination of blocks

Intervention Type PROCEDURE

Supracondylar radial nerve block given first, followed by hematoma block, before fracture reduction.

Interventions

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Supracondylar radial nerve block

Supracondylar radial nerve blocks given at the radial nerve not as the same location of the fracture site, prior to fracture reduction.

Intervention Type PROCEDURE

Hematoma block

Injection of analgesia into the hematoma that forms surrounding the wrist fracture.

Intervention Type PROCEDURE

Combination of blocks

Supracondylar radial nerve block given first, followed by hematoma block, before fracture reduction.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* 18 years of age or older
* Patients admitted to the ECC with a distal radius fracture requiring closed reduction
* Patient must be willing and able to provide informed consent to the study

Exclusion Criteria

* Under 18 years of age
* Pregnant
* Prisoner
* Allergy to lidocaine
* Patients unable to provide informed consent and/or perform study-related activities
* Patients undergoing procedural sedation
* Patients may be excluded at the discretion of the investigator based on their clinical judgment, if the participant no longer meets criteria, and/or if the health or safety of the patient may be impacted by taking part in the study.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sarasota Memorial Health Care System

OTHER

Sponsor Role lead

Responsible Party

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Aaron Grossberg

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Aaron Grossberg, DO

Role: PRINCIPAL_INVESTIGATOR

Sarasota Memorial Health Care System

Locations

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Sarasota Memorial Health Care System

Sarasota, Florida, United States

Site Status

Countries

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United States

References

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Gottlieb M, Cosby K. Ultrasound-guided hematoma block for distal radial and ulnar fractures. J Emerg Med. 2015 Mar;48(3):310-2. doi: 10.1016/j.jemermed.2014.09.063. Epub 2014 Dec 9.

Reference Type BACKGROUND
PMID: 25497895 (View on PubMed)

Tseng PT, Leu TH, Chen YW, Chen YP. Hematoma block or procedural sedation and analgesia, which is the most effective method of anesthesia in reduction of displaced distal radius fracture? J Orthop Surg Res. 2018 Mar 27;13(1):62. doi: 10.1186/s13018-018-0772-7.

Reference Type BACKGROUND
PMID: 29580286 (View on PubMed)

Siebelt M, Hartholt KA, van Winden DFM, Boot F, Papathanasiou D, Verdouw BC, de Vries MR, Mathijssen NM, Kraan GA. Ultrasound-Guided Nerve Blocks as Analgesia for Nonoperative Management of Distal Radius Fractures-Two Consecutive Randomized Controlled Trials. J Orthop Trauma. 2019 Apr;33(4):e124-e130. doi: 10.1097/BOT.0000000000001388.

Reference Type BACKGROUND
PMID: 30893220 (View on PubMed)

Oakley B, Busby C, Kulkarni S, Arnold SJ, Kulkarni SS, Ollivere BJ. Manipulation of distal radius fractures: a comparison of Bier's block vs haematoma block. Ann R Coll Surg Engl. 2023 May;105(5):434-440. doi: 10.1308/rcsann.2022.0116. Epub 2022 Oct 14.

Reference Type BACKGROUND
PMID: 36239973 (View on PubMed)

Maia GAS, Cunha JC, Feijo CQ, Leal DM, Moreira JJ, Herrero CFPDS. Radial Nerve Supracondylar Block Versus Fracture Hematoma Block. Comparison of Their Efficacy in Cases of Fractures of the Distal Third of the Radius. Rev Bras Ortop (Sao Paulo). 2023 Aug 30;58(4):e557-e562. doi: 10.1055/s-0043-1768623. eCollection 2023 Aug.

Reference Type BACKGROUND
PMID: 37663190 (View on PubMed)

Handoll HH, Madhok R, Dodds C. Anaesthesia for treating distal radial fracture in adults. Cochrane Database Syst Rev. 2002;2002(3):CD003320. doi: 10.1002/14651858.CD003320.

Reference Type BACKGROUND
PMID: 12137688 (View on PubMed)

Haley CB, Beauchesne AR, Fox JC, Nelson AM. Block Time: A Multispecialty Systematic Review of Efficacy and Safety of Ultrasound-guided Upper Extremity Nerve Blocks. West J Emerg Med. 2023 Jun 30;24(4):774-785. doi: 10.5811/westjem.56058.

Reference Type BACKGROUND
PMID: 37527380 (View on PubMed)

Martinez-Arboleda JJ, Moreno M, Diaz-Solorzano JP, Mejia-Grueso A. Ultrasound-guided supracondylar radial nerve block for closed reduction of a distal radius fracture in the emergency department: Case report. Trauma Case Rep. 2024 Sep 25;54:101116. doi: 10.1016/j.tcr.2024.101116. eCollection 2024 Dec.

Reference Type BACKGROUND
PMID: 39399762 (View on PubMed)

Che Daud AZ, Mohd Nayan NA, Ahmad A, Alrashdi M, Kadar M, Mohd Poot EF. Distal radius fracture rehabilitation: A bibliometric and scoping review. J Hand Ther. 2025 Jul 3:S0894-1130(25)00089-4. doi: 10.1016/j.jht.2025.05.016. Online ahead of print.

Reference Type BACKGROUND
PMID: 40615307 (View on PubMed)

Abbasi S, Garjani N, Mahshidfar B, Farsi D, Mofidi M, Hafezimoghadam P, Rezai M, Javan A. Comparative Study of Radial and Median Nerve Blocks with Hematoma Block under Ultrasound Guide in Distal Radius Fracture Reduction: A Randomized Clinical Trial. Med J Islam Repub Iran. 2023 Oct 23;37:113. doi: 10.47176/mjiri.37.113. eCollection 2023.

Reference Type BACKGROUND
PMID: 38145179 (View on PubMed)

Other Identifiers

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25-MEDI-58

Identifier Type: -

Identifier Source: org_study_id

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