Lung Ultrasound for the Detection of Volume Overload in Patients With Severe Preeclampsia
NCT ID: NCT07261956
Last Updated: 2025-12-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
202 participants
INTERVENTIONAL
2025-08-25
2026-01-31
Brief Summary
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The study will be a prospective, longitudinal observational study with a diagnostic validation component. It will involve patients with a diagnosis of severe preeclampsia who meet specific inclusion criteria. Each participant will undergo a clinical exam and a lung ultrasound, which will assess eight zones of the lungs. The total number of B-lines-a sign of interstitial edema-will be documented.
Data will be collected at three key times: upon admission, in the immediate postpartum period (within 24 hours of delivery), and 7-10 days postpartum. The results from the LUS will be compared to clinical signs like shortness of breath, rapid breathing, crackling sounds in the lungs, and oxygen saturation levels.
The expected impact of this research is to provide evidence that LUS is a valuable, non-invasive, and accessible tool for the early detection of pulmonary congestion in patients with severe preeclampsia. This could lead to improved clinical decision-making and a reduction in maternal respiratory complications.
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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Severe preeclampsia
Pregnant subjects (24 weeks - 41 weeks) with severe preeclampsia
Lung ultrasound
Lung ultrasounf at three moments (at admission, before delivery and immediate post partum) to determine B Lines
Interventions
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Lung ultrasound
Lung ultrasounf at three moments (at admission, before delivery and immediate post partum) to determine B Lines
Eligibility Criteria
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Inclusion Criteria
* Gestational age 24 weeks - 41 weeks.
Exclusion Criteria
* Known heart disease.
* Diagnosis of lung edema at admission
* Body mass index \> 40
* Need for immediate delivery
FEMALE
No
Sponsors
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Saint Thomas Hospital, Panama
OTHER
Responsible Party
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Osvaldo A. Reyes T.
Head of Research Department
Principal Investigators
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Osvaldo Reyes, MD
Role: STUDY_DIRECTOR
Saint Thomas Hospital, Panama
Locations
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Saint Thomas Hospital
Panama City, Provincia de Panamá, Panama
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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4377
Identifier Type: -
Identifier Source: org_study_id
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