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The Role of Lung and Diaphragm Ultrasonography in Predicting Clinical Progression in Hypoxemic Respiratory Failure

NCT ID: NCT06706830

Last Updated: 2024-11-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

91 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-01-01

Study Completion Date

2024-08-23

Brief Summary

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The goal of this observational study is to evaluate whether the risk of intubation in patients with hypoxemic respiratory failure who were monitored in the intensive care unit and received non-invasive mechanical ventilation and high-flow nasal oxygen treatment could be predicted using lung and diaphragm ultrasound.

The main question it aims to answer is:

Can lung and diaphragm ultrasound predict the risk of intubation in patients with hypoxemic respiratory failure?

Detailed Description

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Between January 1, 2024, and May 1, 2024, the diaphragm thickness fraction, excursion, LUS score, ROX index, and the LUSS/ROX index ratio were evaluated using lung and diaphragm ultrasound in 91 patients admitted to the intensive care unit with a diagnosis of hypoxemic respiratory failure. These evaluations were performed at the 6th, 12th, 24th, and 48th hours of their ICU stay, and during intubation if the decision for intubation was made

Conditions

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Diaphragm Ultrasonography Lung Ultrasound Hypoxemic Respiratory Failure

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Hypoxemic

Patients whose partial oxygen levels are low

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

-PaO2 \<60 mmHg detected in arterial blood gas samples at the time of admission to the intensive care unit

Exclusion Criteria

* Under the age of 18
* History of lung and diaphragm surgery
* Congenital, acquired or traumatic diaphragmatic hernia
* Diaphragm paralysis
* Hemodynamic instability requiring vasoactive drug support
* Do not agree to participate in the study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Simge Evren

OTHER

Sponsor Role lead

Responsible Party

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Simge Evren

Principal Investigator

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Namigar Turgut

Role: STUDY_DIRECTOR

Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization

Locations

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Prof. Dr. Cemil Tascıoglu City Hospital

Istanbul, Şişli, Turkey (Türkiye)

Site Status

Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization

Istanbul, Şişli, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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291

Identifier Type: -

Identifier Source: org_study_id