T1 Tissue Mapping as a Non Invasive Biomarker for Quantification of Chronic Thyroid Related Microscopic Myocardial Fibrosis.

NCT ID: NCT07247981

Last Updated: 2025-11-25

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Total Enrollment: 40 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2026-01-01
• Study Completion Date: 2027-01-31

Brief Summary

CMR T1 tissue mapping helps in detection and quantification of the microscopic myocardial fibrosis and is more accurate and non invasive maneuver.

Detailed Description

Chronic thyroid diseased patients either hypo or hyperthyroidism may develop arrhythmias or even atrial fibrillation which is worrisome. And since early detection provides the early management, T1 tissue mapping of the heart provides accurate quantification of the myocardial fibrosis throughout the imaged organ.

Conditions

Chronic Thyroid Disease

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: CROSS_SECTIONAL

Eligibility Criteria

Inclusion Criteria

• patients with chronic thyroid disease.

Exclusion Criteria

• patients with other chronic illnesses ( diabetes, hypertension, .. etc).
• patients received neck radiation therapy.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Lina Mohamed Farid

Lina Mohamed Farid

Responsibility Role: PRINCIPAL_INVESTIGATOR

Central Contacts

Lina M Farid, MSc

Role: CONTACT

Lina.m.farid@gmail.com

01063455559

Moustafa A Sayyed, MD

Role: CONTACT

Most.rad@aun.edu.eg

01092300511

Other Identifiers

CMR T1 tissue mapping

Identifier Type: -

Identifier Source: org_study_id