Balance Evaluation in Adult Hemophilia

NCT ID: NCT07243912

Last Updated: 2025-11-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

81 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-09-10

Study Completion Date

2025-10-20

Brief Summary

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Introduction: Recurrent hemarthrosis in hemophilia can cause deterioration of static and dynamic balance in hemophilia. Studies in AwH report decreased dynamic balance, but consistent results regarding static balance are lacking. The causes of the decrease in dynamic balance and its associated parameters have been under explored.

Aim: To investigate static and dynamic balance in AwH compared to healthy controls and factors such as joint health, physical activity and kinesiophobia that may affect dynamic balance.

Methods: This cross-sectional controlled study included 41 AwH and 40 healthy controlled, totally 81 man and study groups determined as Hemophilia Group (HG) and Control Group (CG). Static (Static Stability Test) and dynamic balance (Limits of Stability Test (LoS) Test) were assessed Pro-kin Technobody Posturographic Platform; physical activity level with International Physical Activity Questionnaire (IPAQ) for all groups. Joint health and kinesiophobia were assessed with Hemophilia Joint Health Score and Tampa Scale for Kinesiophobia (TSK) for HG, respectively. Participants' age, height and weight were questioned in both groups, as well as type and severity of hemophilia, type of treatment, and work/job status in HG.

Detailed Description

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Conditions

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Postural Balance

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Control Group

Healthy individual

Postural balance assessment

Intervention Type DIAGNOSTIC_TEST

Static and dynamic balance was analyzed with the posturographic platform.

Hemophilia Group

Adults with Hemophilia

Postural balance assessment

Intervention Type DIAGNOSTIC_TEST

Static and dynamic balance was analyzed with the posturographic platform.

Interventions

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Postural balance assessment

Static and dynamic balance was analyzed with the posturographic platform.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

Severe or moderate hemophilia A or B

Exclusion Criteria

Diabetus mellitus, hemiplegia, rheumatoid arthritis, Alzheimer's disease, Parkinson's disease, all vestibular system pathologies, lower extremity surgery within the last 6 months, using a walking aid.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Ayse Merve TAT

OTHER

Sponsor Role lead

Responsible Party

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Ayse Merve TAT

Assistant Professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Ayşe M Tat, Asst Prof

Role: PRINCIPAL_INVESTIGATOR

Yuzuncu Yil University

Locations

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Van Yüzüncü Yıl University

Van, Tuşba, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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YuzuncuYil2025

Identifier Type: -

Identifier Source: org_study_id

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