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Use of Lactate-to-Albumin, CRP-to-Albumin, and Procalcitonin-to-Albumin Ratios to Predict Mortality in ICU Patients

NCT ID: NCT07242027

Last Updated: 2025-11-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

212 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-03-21

Study Completion Date

2025-09-20

Brief Summary

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This observational study aims to determine whether three blood test ratios - lactate-to-albumin, CRP-to-albumin, and procalcitonin-to-albumin - can predict in-hospital mortality among critically ill adults. The study includes all adult patients admitted in 2024 to the ICU Ward B at the Silesian Center for Heart Diseases (SCCS) in Zabrze. Researchers will analyze retrospective clinical and laboratory data from electronic medical records, including lab values collected at ICU admission, patient demographics, diagnoses, and outcomes. The biomarker ratios will be manually calculated in Excel and statistically evaluated. The main goal is to assess whether these ratios are associated with patient survival and to identify predictive cut-off values to support early risk stratification in the ICU setting.

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Detailed Description

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Conditions

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Sepsis Respiratory Failure Cardiac Arrest Circulatory Failure Critical Illness Sudden Cardiac Arrest

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Survivors

Critically ill adult patients admitted to the ICU who survived hospitalization and were discharged alive.

No interventions assigned to this group

Non-Survivors

Critically ill adult patients admitted to the ICU who died during the course of hospitalization.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 18 years
* Admission to ICU in 2024
* Availability of data for lactate, CRP, procalcitonin, and albumin

Exclusion Criteria

* Missing outcome data (e.g. unknown survival status)
* Lack of laboratory parameters necessary for ratio calculation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Silesia

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Department of Acute Medicine, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland

Zabrze, Silesian Voivodeship, Poland

Site Status

Countries

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Poland

Other Identifiers

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SUM-SKNIPG-LARCARPAR-ICU-2025

Identifier Type: -

Identifier Source: org_study_id

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