Efficacy of Different Types of Chemical Peels in the Treatment of Acne Vulgaris
NCT ID: NCT07240051
Last Updated: 2025-11-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
90 participants
INTERVENTIONAL
2024-03-09
2024-07-12
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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glycolic acid group
30 patients received 50% glycolic acid peels
Glycolic acid peel alone
Using a cotton tip applicator, a single coat of commercially prepared 50% GA peeling agent was evenly applied to the patient's face. Neutralization of the peel was done on reaching uniform erythema (endpoint) within 3-5 minutes. If frosting was observed in any area before the set time or endpoint, the area was neutralized with sodium bicarbonate
Salicylic acid group
30 patients received Salicylic acid 30%
salicylic acid
Using a cotton tip applicator, a single coat of commercially prepared 30% SA peeling agent was evenly applied to the patient's face, moving from the forehead and advancing to the cheeks, chin, glabella, nose, and perioral area. Once white crystallization appeared, patients were asked to wash their faces with water.
Modified Jessener group
30 patients received MJ peel
modified jessener
Commercially prepared MJ peel was applied using a gauze piece and light hand pressure. A single coat of peel was uniformly applied over the entire face. The coat was allowed to dry completely until erythema or frosting occurred, at which point patients were asked to wash their faces with cold water.
Interventions
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Glycolic acid peel alone
Using a cotton tip applicator, a single coat of commercially prepared 50% GA peeling agent was evenly applied to the patient's face. Neutralization of the peel was done on reaching uniform erythema (endpoint) within 3-5 minutes. If frosting was observed in any area before the set time or endpoint, the area was neutralized with sodium bicarbonate
salicylic acid
Using a cotton tip applicator, a single coat of commercially prepared 30% SA peeling agent was evenly applied to the patient's face, moving from the forehead and advancing to the cheeks, chin, glabella, nose, and perioral area. Once white crystallization appeared, patients were asked to wash their faces with water.
modified jessener
Commercially prepared MJ peel was applied using a gauze piece and light hand pressure. A single coat of peel was uniformly applied over the entire face. The coat was allowed to dry completely until erythema or frosting occurred, at which point patients were asked to wash their faces with cold water.
Eligibility Criteria
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Inclusion Criteria
* post-acne hyperpigmentation
* a minimum age of 18 years
* skin phototype III or IV
Exclusion Criteria
* active infection in the treatment area (e.g., verrucae and herpes simplex)
* systemic disease (hypertension, diabetes, or bleeding tendency)
* systemic retinoid or laser treatment within the last 6 months
* history of keloidal tendency or Aspirin sensitivity.
65 Years
ALL
Yes
Sponsors
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Nahla Maher Mahmoud Mahran
OTHER
Responsible Party
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Nahla Maher Mahmoud Mahran
lecturer of Dermatology
Locations
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Cairo University
Cairo, , Egypt
Countries
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Other Identifiers
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MS-327-2023
Identifier Type: -
Identifier Source: org_study_id
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