The Effects of Liquid IV's Multi-Ingredient Recovery Supplement on Muscle Recovery Following Exercise
NCT ID: NCT07224867
Last Updated: 2025-11-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
30 participants
INTERVENTIONAL
2025-12-01
2026-05-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
DOUBLE
Study Groups
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proprietary post workout recovery supplement
Liquid I.V. post workout recovery powder mixture
proprietary post workout recovery supplement
proprietary post workout recovery supplement
Control Treatment
inactive/inert placebo mixture
Control placebo
inactive/inert placebo mix
Interventions
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proprietary post workout recovery supplement
proprietary post workout recovery supplement
Control placebo
inactive/inert placebo mix
Eligibility Criteria
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Inclusion Criteria
* Must be recreationally trained or trained/developmental as previously defined (McKay et al., 2021).
* Able to read and write in English.
* Cessation of current use of tart cherry extract, protein powders, essential amino acids/BCAAs, collagen/collagen peptides, or anabolic agents for a minimum of 1-weeks prior to, and throughout the duration of the study.
* Willing to maintain regular supplement routine otherwise during the trial, and will not introduce or discontinue a supplement, other than what was previously mentioned.
* Will not participate in any strenuous exercise for a minimum of 1-week prior exercise performance assessments, as well as during the days of exercise testing. Strenuous exercise as defined for this study includes ½ and full marathons (or more), heavy (i.e.,\>80% 1RM) lifting, and any high intensity, physical activity that could make your muscles sore.
* During the study, you agree not to take any NSAIDs or other anti-inflammatory medications.
Exclusion Criteria
* Vegan, unwilling to consume animal bovine collagen
* Highly trained/national level or professional athlete
* Known diagnosis of any cardiovascular, metabolic, musculoskeletal, endocrine, or renal disease/disorder.
* Recent musculoskeletal injury (\<3-months)
* Recent orthopaedic surgery (\<12-months)
* History or current malignancy.
* Current respiratory infection (i.e., cold) or high temperature (fever) within the past 4-weeks.
* Previous gastrointestinal surgery within the past 12 months.
* Regular smoker.
* Regular drinker (\>14 drinks per week).
* Those regularly using anti-inflammatory drugs within the last 4-weeks.
* Current use of prescription medications that may influence adaptation to exercise (hormone therapies, peptides, etc.).
* Allergies to study-related materials.
* Any condition that impairs their ability to complete the required exercises.
* Female subjects must not be pregnant or lactating.
* Are unable to provide informed consent or are non-English speakers.
* Presently using GLP-1 medications.
18 Years
55 Years
ALL
Yes
Sponsors
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Applied Science & Performance Institute
INDUSTRY
Responsible Party
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Principal Investigators
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Eric Sikorski, PhD
Role: PRINCIPAL_INVESTIGATOR
Applied Science and Performance Institute
Locations
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Applied Science & Performance Institute
Tampa, Florida, United States
Countries
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Central Contacts
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Facility Contacts
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References
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Skurvydas A, Brazaitis M, Venckunas T, Kamandulis S. Predictive value of strength loss as an indicator of muscle damage across multiple drop jumps. Appl Physiol Nutr Metab. 2011 Jun;36(3):353-60. doi: 10.1139/h11-023. Epub 2011 May 16.
Shimomura Y, Yamamoto Y, Bajotto G, Sato J, Murakami T, Shimomura N, Kobayashi H, Mawatari K. Nutraceutical effects of branched-chain amino acids on skeletal muscle. J Nutr. 2006 Feb;136(2):529S-532S. doi: 10.1093/jn/136.2.529S.
Connolly DA, McHugh MP, Padilla-Zakour OI, Carlson L, Sayers SP. Efficacy of a tart cherry juice blend in preventing the symptoms of muscle damage. Br J Sports Med. 2006 Aug;40(8):679-83; discussion 683. doi: 10.1136/bjsm.2005.025429. Epub 2006 Jun 21.
Blomstrand E, Eliasson J, Karlsson HK, Kohnke R. Branched-chain amino acids activate key enzymes in protein synthesis after physical exercise. J Nutr. 2006 Jan;136(1 Suppl):269S-73S. doi: 10.1093/jn/136.1.269S.
Impellizzeri FM, Maffiuletti NA. Convergent evidence for construct validity of a 7-point likert scale of lower limb muscle soreness. Clin J Sport Med. 2007 Nov;17(6):494-6. doi: 10.1097/JSM.0b013e31815aed57.
Laurent CM, Green JM, Bishop PA, Sjokvist J, Schumacker RE, Richardson MT, Curtner-Smith M. A practical approach to monitoring recovery: development of a perceived recovery status scale. J Strength Cond Res. 2011 Mar;25(3):620-8. doi: 10.1519/JSC.0b013e3181c69ec6.
Other Identifiers
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Pro00089373
Identifier Type: -
Identifier Source: org_study_id
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