Knee Strengthening With Hip vs. Ankle Exercises in Women With Patellofemoral Pain Syndrome

NCT ID: NCT07210060

Last Updated: 2025-10-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-07-01

Study Completion Date

2024-07-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Eight weeks of telehealth-based supervised exercise effectively reduced DKV and pain in women with anterior knee pain. Both intervention groups demonstrated comparable benefits.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This study compared the effects of knee strengthening combined with either hip or ankle joint exercises on dynamic knee valgus (DKV), visual analogue scale (VAS) scores during activity, tendon stiffness, muscle structure, ankle range of motion, and muscle strength in women with anterior knee pain. Forty-five female recreational athletes aged 20-40 with anterior knee pain were randomly assigned to three groups: hip + knee exercises (HK group, n = 15), ankle + knee exercises (AK group, n = 15), and stretching alone (control group, n = 15). The HK and AK groups received supervised telehealth-based exercise sessions (30 minutes/day, 3 times/week for 8 weeks), while the control group received only an educational pamphlet. Assessments were conducted at baseline, 4 weeks, and 8 weeks.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Patellofemoral Pain Syndrome Anterior Knee Pain Exercise Therapy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

HK group

hip + knee joint exercise group

Group Type EXPERIMENTAL

hip + knee joint exercise group

Intervention Type OTHER

Hip: squat, glute bridge and gluteus medius exercise Knee: knee flexor and extensor, isometric squat hold

AK group

ankle + knee joint exercise group

Group Type EXPERIMENTAL

ankle + knee joint exercise group

Intervention Type OTHER

Knee: knee flexor and extensor, isometric squat hold Ankle: plantar flexor, dorsi flexor and lunge

Stretching group

Stretching group

Group Type SHAM_COMPARATOR

Stretching group

Intervention Type OTHER

Education Handout on Lower Limb Stretching

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

hip + knee joint exercise group

Hip: squat, glute bridge and gluteus medius exercise Knee: knee flexor and extensor, isometric squat hold

Intervention Type OTHER

ankle + knee joint exercise group

Knee: knee flexor and extensor, isometric squat hold Ankle: plantar flexor, dorsi flexor and lunge

Intervention Type OTHER

Stretching group

Education Handout on Lower Limb Stretching

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. Female recreational athletes aged 20-40 years who engage in regular exercise
2. Experiencing pain in the anterior or surrounding patella during at least two or more of the following activities: walking, running, jumping, kneeling, squatting, climbing stairs, or prolonged sitting
3. A pain index of 3 or higher on the Numeric Pain Rating Scale (NPRS) and symptoms persisting for at least 3 months
4. Knee pain unrelated to trauma.

Exclusion Criteria

1. Inability to operate a smartphone or computer
2. History of fractures or surgeries involving the hip, knee, ankle, or foot
3. History of meniscus, knee ligament injuries, or ankle sprains within the last six months
4. Knee ligament laxity, inflammation, swelling, patellar dislocation, or subluxation
5. Cognitive impairment or inability to follow simple instructions
6. History of cardiovascular or neurological disorders
7. Advised by a physician to avoid exercise. Use of over-the-counter pain medication was not an exclusion criterion.
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Kaohsiung Medical University Chung-Ho Memorial Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Nai-Jen Chang

Tainan City, Kaohsiung City, Taiwan

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Taiwan

Provided Documents

Download supplemental materials such as informed consent forms, study protocols, or participant manuals.

Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

KMUHIRB-E(I)-20220334

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

PNF Stretching for TKA on ROM
NCT00797875 UNKNOWN NA