Clinical and Biological Signs of Dapagliflozin Overdose in ICU Patients With Metformin Poisoning

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-04-11

Study Completion Date

2026-04-11

Brief Summary

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This study looks at patients admitted to intensive care for drug poisoning involving metformin, a common diabetes medication. Researchers will compare two groups: patients who overdosed on metformin alone and those who took both metformin and dapagliflozin, another diabetes drug. The goal is to find clinical or laboratory signs that could help doctors quickly recognize a dapagliflozin overdose in this context, which could improve treatment and patient outcomes.

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Detailed Description

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Conditions

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Drug Overdose Metformin Dapagliflozin Lactic Acidosis Diabetic Ketoacidosis Intensive Care Units

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Adults aged 18 years or older
* Admission to an intensive care unit (ICU) due to acute drug poisoning
* Documented exposure to either:
* Metformin alone
* Metformin in combination with dapagliflozin