Inflammatory Responses After CrossFit and Resistance Trainings in Untrained Subjects

NCT ID: NCT07190924

Last Updated: 2025-09-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-11-08

Study Completion Date

2022-04-17

Brief Summary

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Considering the remarkable increase of the fitness programs, the purpose of this study was to assess and compare the effect of Crossfit (CF) and periodized resistance (RT) trainings on inflammatory/oxidative responses in untrained individuals.

Twenty-four participants (20 men and 4 women, age= 25.7 ± 2.2 years, BMI= 25.7 kg.m-2) were randomly assigned into 12 weeks of these trainings with a rate of five sessions/week. Before and after intervention, participants anthropometric data and graded exercise tests were performed. Before (pre), immediately after (post) and 60min after test (p60) a 20mL venous blood sample were drawn for a later measure of c-reactive protein (CRP), interleukin 1 beta (IL-1ß), tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6), interleukin 10 (IL-10), thiobarbituric acid reactive substances (TBARS), antioxidant enzymes catalase (CAT) and glutathione peroxidase (GPx).

Detailed Description

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Conditions

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Inflammation Oxidative Stress Plasma Volume Hormones

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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CrossFit

High intensity functional training

Group Type EXPERIMENTAL

12 week training

Intervention Type BEHAVIORAL

Anti-inflammatory and oxidative environment following 12-weeks of CF training by evaluating inflammatory markers and oxidative precursors in untrained participants

Resistance

Periodized resistance training

Group Type EXPERIMENTAL

12 week training

Intervention Type BEHAVIORAL

Anti-inflammatory and oxidative environment following 12-weeks of resistance training by evaluating inflammatory markers and oxidative precursors in untrained participants

Interventions

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12 week training

Anti-inflammatory and oxidative environment following 12-weeks of CF training by evaluating inflammatory markers and oxidative precursors in untrained participants

Intervention Type BEHAVIORAL

12 week training

Anti-inflammatory and oxidative environment following 12-weeks of resistance training by evaluating inflammatory markers and oxidative precursors in untrained participants

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Participants must be non-smokers,
* Participants should not suffer from respiratory issues
* Participants should have healthy kidney and liver
* Participants have no metabolic and neurological disorders

Exclusion Criteria

* The use of medications during the previous 4 weeks
* Consumption of any product related to anti-inflammatory/oxidative supplements
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Habil Hamdouni

OTHER

Sponsor Role lead

Responsible Party

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Habil Hamdouni

Doctor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Institut Supérieur du Sport et de l'Education Physique de Ksar-Saïd

Aryanah, Ariana Governorate, Tunisia

Site Status

Countries

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Tunisia

Other Identifiers

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ISS-1386

Identifier Type: -

Identifier Source: org_study_id

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