Predictive Value of CEA and ctDNA in Lung Cancer Recurrence

NCT ID: NCT07170046

Last Updated: 2025-09-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-09-15

Study Completion Date

2027-08-01

Brief Summary

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The study aims to investigate the predictive value of CEA levels for postoperative recurrence in the highly sensitive CEA lung cancer patients and to explore whether the dynamic changes of postoperative CEA and MRD in this population are related.This study was carried out to accurately predict the recurrence time, save the time and cost of changing the intervention strategy, and provide more personalized treatment for patients.

Detailed Description

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This study will collect two groups of cohorts: prospective and retrospective.

Conditions

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Lung Carcinoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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retrospective cohort

The clinical information of the population in this cohort was retrospectively collected.

No interventions assigned to this group

prospective cohort

The clinical information of the population in this cohort was prospectively collected.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Preoperative CEA \> 5mg/l
2. MRD testing was conducted before the operation
3. The primary lesion was resected through surgery
4. There should be at least two CEA and MRD follow-up tests within 2 years after the operation
5. Postoperative pathology confirmed it as a malignant lung tumor

Exclusion Criteria

1. Those without available imaging records
2. Patients with a history of malignant tumors within the past five years
3. Patients with secondary lung cancer
Minimum Eligible Age

15 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Guangdong Provincial People's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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KY2025-310

Identifier Type: -

Identifier Source: org_study_id

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