The Prognostic and Predictive Value of the CA-125 Marker in Lung Cancer Monitoring

NCT ID: NCT02437760

Last Updated: 2015-05-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-02-28

Study Completion Date

2018-02-28

Brief Summary

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The tumor associated CA-125antigen for diagnosis and follow-up of ovarian cancer was well defined. Increased serum CA125 level may have many diagnoses other than ovarian cancer, including breast, colorectal and lung cancer. 80% lung cancer patients were diagnosed at advanced stage. Malignant pleural effusion secondary to lung cancer represented the condition of cancer cell involved pleura.

The CA-125 level may reflect the extent of tumor involved in pleura (tumor burden), it could be correlated with the prognosis. This study was performed to examine the properties of CA-125 by measuring pleural and blood CA-125 levels in lung cancer with or without malignant pleural effusion; meanwhile to examine whether the rate of decline in CA 125 during primary therapy as a surrogate indicator for survival.

Detailed Description

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Conditions

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Lung Cancer

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Interventions

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serum and pleural effusion CA-125 level

serum and pleural effusion(if exist) CA-125 are collected:

* at time of diagnosis
* every 3 month during treatment
* stop at the progression or after 12 months

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Histologically proved lung cancer

Exclusion Criteria

* History of other cancers within the past 5 years
* Pregnancy or breast milk feeding
* TB pleuritis and peritonitis
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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E-DA Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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E-DA hospital

Kaohsiung City, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Jiun-Ting Wu, MD

Role: CONTACT

886-07-6150011 ext. 5026

Facility Contacts

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Jiun-Ting Wu, MD

Role: primary

886-7-615-0011 ext. 5026

Other Identifiers

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EMRP49103N

Identifier Type: -

Identifier Source: org_study_id

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