Outcome of Bronchoscopy in FB Aspiration

NCT ID: NCT07150689

Last Updated: 2025-09-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

75 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-10-31

Study Completion Date

2026-10-31

Brief Summary

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Outcome of Bronchoscopy in Pediatric patient with foreign body aspiration

Detailed Description

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Conditions

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Foreign Body Aspiration

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Masking Description

Study Groups

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Rigid Bronchoscopy

Standard of care in most pediatric centers; performed under general anesthesia to visualize and remove FB. Gold standard for both diagnosis and treatment

Group Type ACTIVE_COMPARATOR

Rigid bronchoscopy

Intervention Type PROCEDURE

Participants will undergo rigid bronchoscopy under general anesthesia using an age-appropriate rigid bronchoscope. The airway will be systematically inspected. Any identified foreign body will be removed using appropriate retrieval devices (optical forceps, retrieval basket, suction). Post-removal, the airway will be re-examined to confirm clearance and detect trauma.

Flexible Bronchoscop

Flexible scope used for diagnosis and sometimes removal (especially in distal airways or when FB is small). Evaluate if less invasive flexible bronchoscopy can be effective.

Group Type EXPERIMENTAL

Flexible scope

Intervention Type PROCEDURE

Participants will undergo flexible fiberoptic bronchoscopy under sedation or general anesthesia. The bronchoscope will be inserted transorally or transnasally. The airway will be inspected, and foreign body retrieval attempted using retrieval baskets, forceps, or cryoprobe

Combined Approach

Initial flexible bronchoscopy for diagnosis and airway inspection, followed by rigid bronchoscopy for removal if needed. Compare efficiency and safety of combined method.

Group Type EXPERIMENTAL

Combined Flexible-Rigid Bronchoscopy

Intervention Type PROCEDURE

Initial flexible bronchoscopy will be performed to locate the foreign body and inspect distal airways, followed by rigid bronchoscopy for definitive removal.

Imaging-Guided Approach

High-resolution CT or virtual bronchoscopy first; bronchoscopy only if imaging suggests FB. Assess if imaging can reduce unnecessary bronchoscopies.

Group Type EXPERIMENTAL

Imaging-Guided Bronchoscopy

Intervention Type PROCEDURE

Participants will undergo pre-procedure high-resolution CT or virtual bronchoscopy. Based on imaging, either rigid or flexible bronchoscopy will be performed, targeting the suspected location to reduce procedure time.

Interventions

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Rigid bronchoscopy

Participants will undergo rigid bronchoscopy under general anesthesia using an age-appropriate rigid bronchoscope. The airway will be systematically inspected. Any identified foreign body will be removed using appropriate retrieval devices (optical forceps, retrieval basket, suction). Post-removal, the airway will be re-examined to confirm clearance and detect trauma.

Intervention Type PROCEDURE

Flexible scope

Participants will undergo flexible fiberoptic bronchoscopy under sedation or general anesthesia. The bronchoscope will be inserted transorally or transnasally. The airway will be inspected, and foreign body retrieval attempted using retrieval baskets, forceps, or cryoprobe

Intervention Type PROCEDURE

Combined Flexible-Rigid Bronchoscopy

Initial flexible bronchoscopy will be performed to locate the foreign body and inspect distal airways, followed by rigid bronchoscopy for definitive removal.

Intervention Type PROCEDURE

Imaging-Guided Bronchoscopy

Participants will undergo pre-procedure high-resolution CT or virtual bronchoscopy. Based on imaging, either rigid or flexible bronchoscopy will be performed, targeting the suspected location to reduce procedure time.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* children less than 18 years with suspected foreign body aspiration

Exclusion Criteria

* children with congenital airway anomalies other than foreign body aspiration
Minimum Eligible Age

1 Day

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Marsail Refat Kadry

Resident

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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FB bronchoscopy

Identifier Type: -

Identifier Source: org_study_id

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