Clinical and Paraclinical Characteristics of Severe Bronchiolitis in Children From 2 Months to 12 Months at the Children's Hospital 1 in Ho Chi Minh City - Vietnam

NCT ID: NCT04174430

Last Updated: 2019-11-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

51 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-08-01

Study Completion Date

2019-12-01

Brief Summary

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Goal: The aim of this study is to determine the epidemiological, clinical, paraclinical characteristics and treatment of severe bronchiolitis at the Children Hospital N01 in 2001-2002.

Materials and method: in this cross-sectional study, specimens of 51 patients with severe bronchiolitis at the Children Hospital N01 from March, 1 st 2001 to February, 28th 2002 are described and analyzed.

Detailed Description

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Conditions

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Epidemiological, Clinical, Paraclinical Characterictics of Severe Bronchiolitis

Study Design

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Observational Model Type

CASE_CROSSOVER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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mild to moderate bronchiolitis

Bronchiolistis patients without Prematurity (gestational age ≤36 weeks), Low birth weight, Age less than 12 weeks, Chronic pulmonary disease, particularly bronchopulmonary dysplasia (also known as chronic lung disease), Anatomic defects of the airways, Hemodynamically significant congenital heart disease, Immunodeficiency and Neurologic disease

severe bronchiolitis

Intervention Type BIOLOGICAL

Prematurity (gestational age ≤36 weeks), Low birth weight, Age less than 12 weeks,Chronic pulmonary disease, particularly bronchopulmonary dysplasia (also known as chronic lung disease), Anatomic defects of the airways, Hemodynamically significant congenital heart disease, Immunodeficiency, Neurologic disease

Interventions

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severe bronchiolitis

Prematurity (gestational age ≤36 weeks), Low birth weight, Age less than 12 weeks,Chronic pulmonary disease, particularly bronchopulmonary dysplasia (also known as chronic lung disease), Anatomic defects of the airways, Hemodynamically significant congenital heart disease, Immunodeficiency, Neurologic disease

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* children younger from 2-12 months present fever (usually ≤38.3ºC \[101ºF\]) ,cough, and respiratory distress (eg, increased respiratory rate, retractions, wheezing, crackles)
* preceded by a one- to three-day history of upper respiratory tract symptoms (eg, nasal congestion and/or discharge) \]
* Respiratory distress.

Exclusion Criteria

* refusal to give informed consent
* mucus sample Barlett \<=0
Minimum Eligible Age

2 Months

Maximum Eligible Age

12 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Medicine and Pharmacy at Ho Chi Minh City

OTHER

Sponsor Role lead

Responsible Party

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LAN HUYNH CHI

Pediatric Resident, Clinical Physician, Respiratory Department, Children Hospital N01

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Thinh Tan Nguyen, professor

Role: STUDY_DIRECTOR

HoChiMinh Medical University

Locations

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Respiratory

Ho Chi Minh City, District 10, Vietnam

Site Status RECRUITING

Countries

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Vietnam

Central Contacts

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Dung Van Do, A. Professor

Role: CONTACT

+84396722467

Facility Contacts

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Dung Van Do, a professor

Role: primary

84336729444

References

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Saez-Lopez E, Cristovao P, Costa I, Pechirra P, Conde P, Guiomar R; Portuguese Laboratory Network for the Diagnosis of Influenza Infection; Peres MJ, Viseu R, Lopes P, Soares V, Vale F, Fonseca P, Freitas L, Alves J, Pessanha MA, Toscano C, Mota-Vieira L, Veloso RC, Corte-Real R, Branquinho P, Pereira-Vaz J, Rodrigues F, Cunha M, Martins L, Mota P, Couto AR, Bruges-Armas J, Almeida S, Rodrigues D. Epidemiology and genetic variability of respiratory syncytial virus in Portugal, 2014-2018. J Clin Virol. 2019 Dec;121:104200. doi: 10.1016/j.jcv.2019.104200. Epub 2019 Oct 10.

Reference Type RESULT
PMID: 31707201 (View on PubMed)

Related Links

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Other Identifiers

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IRB00010193

Identifier Type: -

Identifier Source: org_study_id

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