Hypophosphatemia and Bronchiolitis

NCT ID: NCT04814641

Last Updated: 2021-03-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-03-21

Study Completion Date

2021-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Bronchiolitis is a major public health problem and the leading cause of paediatric intensive care unit admission in infants. Hypophosphatemia is common in adult intensive care units and was associated with an increase of the duration of mechanical ventilation and the length of stay. Our hypothesis is that hypophosphatemia is common in bronchiolitis and could be a marker of severity.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Hypophosphatemia Bronchiolitis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Infants with hypophosphatemia

Infant less than 3 months with severe bronchiolitis admitted in a pediatric intensive care unit, with hypophosphatemia in the first 5th days

hypophosphatemia occurrence in infants with severe bronchiolitis admitted in a pediatric intensive care unit

Intervention Type BIOLOGICAL

Serum phosphorus level \< 1.55 mmol/L at any time between admission and the 5th day.

Infants without hypophosphatemia

Infant less than 3 months with severe bronchiolitis admitted in a pediatric intensive care unit, without hypophosphatemia

hypophosphatemia occurrence in infants with severe bronchiolitis admitted in a pediatric intensive care unit

Intervention Type BIOLOGICAL

Serum phosphorus level \< 1.55 mmol/L at any time between admission and the 5th day.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

hypophosphatemia occurrence in infants with severe bronchiolitis admitted in a pediatric intensive care unit

Serum phosphorus level \< 1.55 mmol/L at any time between admission and the 5th day.

Intervention Type BIOLOGICAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age \> 7 days and \< 3 months of life
* Admission to the pediatric intensive care unit from 01/11/2016 to 31/03/2020
* With a diagnosis of moderate to severe bronchiolitis according to HAS 2019 criteria

Exclusion Criteria

* Renal Failure and tubulopathy
* Previous disorder of phospho-calcium balance
* Malignant pathology
* Lenght of stay less than 24 hours
* History of cardiac, aortic or hepatic surgery
Minimum Eligible Age

7 Days

Maximum Eligible Age

3 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Hopital Femme Mere Enfant - Groupement Hospitalier Est

Bron, , France

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

France

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Florent Baudin, Dr

Role: CONTACT

4 72 12 97 35 ext. +33

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Florent Baudin, Dr

Role: primary

4 72 12 97 35 ext. +33

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

A289

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Bronchiolitis All-study, SE-Norway
NCT00817466 UNKNOWN PHASE4
Hypertonic Saline for Acute Bronchiolitis
NCT01247064 COMPLETED PHASE4
The Bronchiolitis in Hospitalized Infants Study
NCT05994183 WITHDRAWN EARLY_PHASE1