Culturally Tailored Nutrition Therapy to Improve Dietary Adherence of Type 2 Diabetes Patients in Benin, Africa

NCT ID: NCT07145684

Last Updated: 2025-08-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-10-02

Study Completion Date

2026-10-30

Brief Summary

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The clinical trial aims to assess the effectiveness of the Objectif Santé Diabète Benin (OSanDiaBé), a culturally tailored medical nutrition therapy (MNT), in enhancing diabetes management and nutrition choices. It seeks to answer two main questions:

1. Does the culturally tailored MNT lower HbA1c levels at 12 months compared to usual care?
2. Does it improve dietary behaviors at 12 months compared to usual care?

Detailed Description

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This study is a 12-month, parallel-group, randomized controlled trial involving individuals diagnosed with type 2 diabetes. Participants will be randomly assigned in a 1:1 ratio to either (1) usual care (wait-list control group) or (2) nutrition counseling with group-based education (intervention group). The intervention group will receive the OSanDiaBé resource package, which includes weekly presentations, a workbook, and an Eating Plan based on the 4-A framework of food security. They will participate in four individual home sessions and eight group sessions in the first six months, with no contact between months six and twelve. The primary outcome will be the change in HbA1c levels, while secondary outcomes will include lipid profile, anthropometric measures, dietary adherence, diabetes self-efficacy, and diabetes-related quality of life. All outcomes will be assessed at baseline, 3, 6, and 12 months.

Conditions

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Type 2 Diabetes

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Caregivers Outcome Assessors

Study Groups

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OSanDiaBé intervention

The Objectif Sante Diabète Bénin (OSanDiaBé) intervention group will participate in four individual home sessions and eight group sessions in the first six months, with no contact between months six and twelve. They will receive the OSanDiaBé resource package, which includes weekly presentations, a workbook, and an Eating Plan based on the 4-A framework of food security.

Group Type EXPERIMENTAL

A culturally tailored medical nutrition therapy

Intervention Type BEHAVIORAL

This MNT intervention combines evidence-based menu plans based on the 4A framework of food security with individual nutrition counseling and group diabetes education.

Individual standard care

The Individual standard care arm will be a wait-list control group who will receive standard care, including blood glucose management and general lifestyle advice, and will access the OSanDiaBe program at the end of the intervention for equitable treatment.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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A culturally tailored medical nutrition therapy

This MNT intervention combines evidence-based menu plans based on the 4A framework of food security with individual nutrition counseling and group diabetes education.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* outpatient in one of the participating health centers
* be aged between 40 and 65 years old,
* have a confirmed diagnosis of T2D for a year or longer,
* with uncontrolled diabetes (HbA1c \>7%)
* able to read and write in French or a support who read and write in French
* self-identify as Beninese (born in Benin or have parents from Benin),
* willing to commit to the study and able to attend weekly meetings
* have family member support for behavioral change
* suitable for general diet and lifestyle advice (i.e., no complex diet needs; suitability determined by the referring healthcare provider)
* be willing to provide informed consent to participate.

Exclusion Criteria

* being pregnant, breastfeeding or planning pregnancy,
* participants with type 1 diabetes
* use of medication that might affect weight loss
* planning to travel before the end of the intervention
* have recent cardiovascular complications (e.g., myocardial infarction, stroke, and congestive heart failure),
* currently involved in a similar nutritional educational program (to avoid contamination bias).
* unable to provide consent (e.g., cognitive impairment).
Minimum Eligible Age

40 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fogarty International Center of the National Institute of Health

NIH

Sponsor Role collaborator

University of Arizona

OTHER

Sponsor Role lead

Responsible Party

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Halimatou Alaofe

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Waliou Amoussa-Hounkpatin, PhD

Role: PRINCIPAL_INVESTIGATOR

Université d'Abomey-Calavi

Edward Bedric, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Arizona

Locations

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University of Abomey-Calavi

Cotonou, Littoral Department, Benin

Site Status

Countries

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Benin

Central Contacts

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Halimatou Alaofe, Ph.D

Role: CONTACT

520-369-6356

John Ehiri, PhD

Role: CONTACT

520-626-1355

Facility Contacts

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Waliou Amoussa-Hounkpatin, PhD

Role: primary

+229 97 05 20 20

Halimatou Alaofe, PhD

Role: backup

5203696356

Other Identifiers

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K01TW012422

Identifier Type: NIH

Identifier Source: secondary_id

View Link

STUDY00002233

Identifier Type: -

Identifier Source: org_study_id

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