Functional Exercise Performance in Children With Cerebral Palsy: Is the One-Minute Sit-to-Stand Test an Alternative to the Six-Minute Walk Test

NCT ID: NCT07136129

Last Updated: 2025-08-22

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 78 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2024-12-31
• Study Completion Date: 2025-07-01

Brief Summary

This study investigates the validity of the 1-minute sit-to-stand test (1MSTS) as a practical and time-efficient alternative to the 6-minute walk test (6MWT) for assessing functional exercise capacity in children with spastic cerebral palsy (CP). Children aged 5 to 18 years with spastic hemiplegic CP, classified as Level I or II according to the Gross Motor Function Classification System (GMFCS), will perform both tests on the same day. Cardiopulmonary responses and fatigue will be monitored before and after each test. The study aims to determine whether the 1MSTS can be reliably used in clinical settings as a simpler assessment tool for this population.

Detailed Description

This cross-sectional study was conducted between December 2024 and July 2025 at Kayseri City Hospital with children diagnosed with spastic hemiplegic cerebral palsy, aged 5-18 years, classified as Level I or II on the Gross Motor Function Classification System (GMFCS). Children with severe cognitive impairment, additional neurological disorders, or uncontrolled health conditions were excluded.

Participants completed both the 6-minute walk test (6MWT) and the 1-minute sit-to-stand test (1MSTS) on the same day, in random order. Tests were performed twice, and a 1-hour rest was given between them. Cardiovascular and respiratory parameters (heart rate, oxygen saturation, blood pressure), dyspnea, and leg fatigue were measured before and after each test using standard tools (pulse oximeter, sphygmomanometer, Modified Borg Scale).

The 6MWT followed ATS guidelines. The 1MSTS was performed using a height-adjustable chair without armrests, and participants stood up and sat down repeatedly for one minute. The number of completed repetitions was recorded. This study followed the Declaration of Helsinki, and written informed consent was obtained from all participants and their guardians.

Conditions

Cerebral Palsy; Cerebral Palsy Spastic Hemiplegic

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

Spastic hemiplegic type SP

Individuals between 5 and 18 years of age, diagnosed with spastic hemiplegic type CP and in level I or II according to the Gross Motor Function Classification System (GMFCS) were included.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Having spastic hemiplegic CP between 5-18
• Being level 1 and 2 according to KMFSS

Exclusion Criteria

• Having cognitive/mental problems at a level that may prevent communication
• Having genetic and/or neurological problems in addition to CP
• Having uncontrolled heart disease
• Having any infection Removal Criteria
• The child or his/her parents wanting to leave the study
• Failure to complete the tests to be applied within the scope of the study
• Having an additional disease/surgical operation during the study

• Minimum Eligible Age: 5 Years
• Maximum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Kayseri University

OTHER

Sponsor Role: collaborator

Inonu University

OTHER

Sponsor Role: lead

Responsible Party

Betul Ergun

research asistant

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Kayseri City Hospital

Kayseri, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

SP-1sts6dyt

Identifier Type: -

Identifier Source: org_study_id