Assessment of Diaphragmatic Mobility in Dyspneic Patients With Different Types of Interstitial Lung Diseases

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-02-01

Study Completion Date

2025-06-01

Brief Summary

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dyspnea and impaired exercise capacity in IPF patients can be related, at least in part, to respiratory muscle dysfunction, in particular to diaphragm functionality. Both B-mode and M-mode ultrasound techniques have been employed to assess diaphragm excursion, which measures the distance that the diaphragm is able to move during the respiratory cycle.

recent study using lung ultrasound in assessment of diaphragmatic mobility in IPF patients and found that Diaphragmatic mobility is lower in IPF patients than in healthy controls, especially during deep inspiration. The correlation between reduced FVC and diaphragmatic excursion values in IPF patients can be of interest, since it could represent an index of functional respiratory affection performed by chest ultrasound

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Detailed Description

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Interstitial lung diseases are known to be associated with limitations in daily activities and impaired quality of life. One of the most troublesome burdens for ILD patients is dyspnea during exercise, which extends to the resting state as the disease advances. The causes of dyspnea are suggested to be a progressive decline in total lung capacity (TLC) and vital capacity, along with impairment of diffusion capacity and subsequent development of (primarily hypoxic) respiratory failure along with respiratory muscle dysfunction.

Studies have supported the advantage of ultrasonography in the assessment of diaphragmatic mobility by two-dimensional (BD) or M-mode. Others reported the investigation methods, the criteria for normal and pathological diaphragmatic function, and the perspectives of development in adult patients.

Conditions

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Diaphragm Issues

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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collagen related interstitial lung disease

daiphragm mobility by ultrsound

Intervention Type OTHER

fibrosis score, alveolitis score by CT Chest

spirometry ,DLCo

Intervention Type OTHER

FEV1, FVC, FEV1/FVC, DLCo

idiopathic type (IPF)

daiphragm mobility by ultrsound

Intervention Type OTHER

fibrosis score, alveolitis score by CT Chest

spirometry ,DLCo

Intervention Type OTHER

FEV1, FVC, FEV1/FVC, DLCo

OTHERS(occupational,sarcoid,...)

daiphragm mobility by ultrsound

Intervention Type OTHER

fibrosis score, alveolitis score by CT Chest

spirometry ,DLCo

Intervention Type OTHER

FEV1, FVC, FEV1/FVC, DLCo

Interventions

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daiphragm mobility by ultrsound

fibrosis score, alveolitis score by CT Chest

Intervention Type OTHER

spirometry ,DLCo

FEV1, FVC, FEV1/FVC, DLCo

Intervention Type OTHER

Other Intervention Names

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warricks score

Eligibility Criteria

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Inclusion Criteria

* patients presented to Ain Shams University Hospital outpatient clinic by ILD due to any cause

Exclusion Criteria

* Pregnant females
* Patients with end stage organ failure e.g.: Renal failure, liver cell failure
* Patients with malignancy elsewhere.
* The patients who refuse to be entitled in the study.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No