Chest U/S in Differentiating Lung Congestion & Pneumonia in Adult Critically-ill Patients and Its Prognostic Impact
NCT ID: NCT05636631
Last Updated: 2022-12-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
60 participants
OBSERVATIONAL
2022-11-01
2025-07-31
Brief Summary
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Detailed Description
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Several pathological etiologies can fill the alveolar spaces, with fluid (heart failure), pus (pneumonia which is the commonest), blood (pulmonary hemorrhage), and cells (lung cancer).
Other causes of lung consolidation may include atelectasis, pulmonary edema, infarction, and lung cancer. Chest imaging with CT is regarded as the gold standard modality allowing for the diagnosis of pneumonia in earlier stage and with higher sensitivity and specificity. On the contrary, cardiogenic pulmonary edema (CPE) is defined as alveolar transudation caused by elevated pulmonary capillary hydrostatic pressure secondary to increased pulmonary venous pressure with low-protein content in the interstitial tissue of lung as a result of cardiac dysfunction
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Patients with Pneumonia (1)
Patients presented with symptoms suggestive of pneumonia as fever, tachypnea, cough with sputum. These patients will receive IV fluids \& antibiotics with follow up of sepsis parameters
Chest ultrasound
chest ultrasound as a non invasive, low cost \& bedside device for differentiation \& follow up of lung congestion \& pneumonia
Patients with decongestive heart failure (2)
Patients presented with symptoms suggestive of acute congestive heart failure as dyspnea, orthopnea, bilateral lower limb edema. These patients will receive anti-failure treatment as diuretics, ACE inhibitors \& Beta blockers with follow up of resolving signs of decompensated heart failure
Chest ultrasound
chest ultrasound as a non invasive, low cost \& bedside device for differentiation \& follow up of lung congestion \& pneumonia
Interventions
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Chest ultrasound
chest ultrasound as a non invasive, low cost \& bedside device for differentiation \& follow up of lung congestion \& pneumonia
Eligibility Criteria
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Inclusion Criteria
* Both genders
* Patient with symptoms suggestive of pneumonia
* Patient with symptoms suggestive of acute congestive heart failure
* admitted to Critical care unit
Exclusion Criteria
18 Years
ALL
No
Sponsors
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Assiut University
OTHER
Responsible Party
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Nardin Aymn Boshra
Doctor
Principal Investigators
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Mahmoud Ashry, Professor
Role: STUDY_DIRECTOR
Professor Faculty of Medicine, Assiut University
Locations
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Nardin Aymn
Asyut, Asyut Governorate, Egypt
Countries
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Central Contacts
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References
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Volpicelli G, Cardinale L, Garofalo G, Veltri A. Usefulness of lung ultrasound in the bedside distinction between pulmonary edema and exacerbation of COPD. Emerg Radiol. 2008 May;15(3):145-51. doi: 10.1007/s10140-008-0701-x. Epub 2008 Jan 31.
Lichtenstein DA. BLUE-protocol and FALLS-protocol: two applications of lung ultrasound in the critically ill. Chest. 2015 Jun;147(6):1659-1670. doi: 10.1378/chest.14-1313.
Other Identifiers
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chest US for lung conditions
Identifier Type: -
Identifier Source: org_study_id
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