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Lung Ultrasound in Pleuritic Chest Pain

NCT ID: NCT02107001

Last Updated: 2015-12-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-03-31

Study Completion Date

2015-11-30

Brief Summary

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Chest pain is an alarming symptom and one of the most frequent causes of access to the Emergency Departement. Although chest X-ray remains an essential step in the diagnostic process, several studies showed numerous limitations of radiography which frequently is inconclusive. Ultrasonography is a non-radiating imaging technique. Albeit a wide use of ultrasound, the utilization of ultrasound in the study of the lung has only recently been introduced in the clinical practice. Several studies proved that lung ultrasound is useful in the diagnosis of lung consolidation in community acquired pneumonia. Nowadays, ultrasound is not routinely used in the presence of chest pain. Our hypothesis based on clinical experience is that, in patients with pleuritic chest pain, lung ultrasound is very sensitive in detecting pneumonia and other lung diseases (such as pneumothorax) thus performing better than radiography. The primary aim of this study is to verify, in patients affected by pleuritic chest pain, the accuracy of lung ultrasound compared to chest-X-ray. The secondary aim is to evaluate the accuracy of lung ultrasound consolidations in distinguishing lung consolidation in pneumonia, atelectasis, pulmonary infarction, or tumors.

Detailed Description

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Conditions

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Community Acquired Pneumonia Pleuritis Pulmonary Embolism Lung Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with pleuritic chest pain

Study investigators will perform lung ultrasound in each patient with pleuritic chest pain at inclusion

Lung ultrasound

Intervention Type PROCEDURE

Lung ultrasonography performed and interpreted by a physician (Pulmonologist or Emergency Physician) possessing specific knowledge in the procedure and a training of at least 100 thoracic ultrasonographies in accordance to a prespecified protocol.

Interventions

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Lung ultrasound

Lung ultrasonography performed and interpreted by a physician (Pulmonologist or Emergency Physician) possessing specific knowledge in the procedure and a training of at least 100 thoracic ultrasonographies in accordance to a prespecified protocol.

Intervention Type PROCEDURE

Other Intervention Names

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Lung sonography

Eligibility Criteria

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Inclusion Criteria

* patient aged 18 years and older
* patient affected by thoracic pleuritic pain

Exclusion Criteria

* patient affected by a chronic condition causing thoracic pain
* patient affected by acute cardiovascular diseases (e.g. acute coronary syndrome)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Milan

OTHER

Sponsor Role lead

Responsible Party

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Fabiano Di Marco

M.D., Ph.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Giuseppe Francesco Sferrazza Papa, M.D.

Role: PRINCIPAL_INVESTIGATOR

Respiratory Unit, San Paolo Hospital, Dipartimento Scienze della Salute, Università degli Studi di Milano, Milan, Italy.

Stefano Centanni, M.D, Ph.D.

Role: STUDY_CHAIR

Respiratory Unit, San Paolo Hospital, Dipartimento Scienze della Salute, Università degli Studi di Milano, Milan, Italy.

Giovanni Volpicelli, M.D.

Role: STUDY_DIRECTOR

Emergency Medicine staff Physician San Luigi Gonzaga University Hospital Torino, Italy.

Locations

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Emergency Department, Azienda Ospedaliera Universitaria Careggi, Firenze.

Florence, , Italy

Site Status

USC Pneumologia, Azienda Ospedaliera della Provincia di Lodi

Lodi, , Italy

Site Status

- U.O.C Broncopneumologia, IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano.

Milan, , Italy

Site Status

Emergency Department, San Paolo Hospital

Milan, , Italy

Site Status

Respiratory Unit, San Paolo Hospital, Dipartimento Scienze della Salute, Università degli Studi di Milano.

Milan, , Italy

Site Status

S.O.C. Pneumologia, Ospedale S. Luca, Rovigo.

Rovigo, , Italy

Site Status

- Dipartimento di Medicina d'Urgenza, Ospedale Universitario, S. Luigi Gonzaga, Orbassano (TO).

Turin, , Italy

Site Status

Countries

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Italy

Other Identifiers

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UPP08032014

Identifier Type: -

Identifier Source: org_study_id