Evolution of Pulmonary Ultrasound in Patients Hospitalized for Covid (Coronavirus Disease) 19

NCT ID: NCT04341766

Last Updated: 2020-07-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

106 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-03-31

Study Completion Date

2020-06-30

Brief Summary

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Clinical thoracic ultrasound plays an important role in the exploration, diagnosis and follow-up of thoracic pathologies.

The COVID (Coronavirus Disease) epidemic is leading to a large influx of patients in the emergency department with respiratory disorders. The rapid diagnosis of respiratory disorders in infected patients is important for further management.

Chest ultrasound has already demonstrated its value in the diagnosis of pneumonia in the emergency department with superiority over chest X-ray.

However, there is little data on the thoracic ultrasound semiology of viral pneumonia in general and of COVID in particular.

Detailed Description

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Chest ultrasound has already shown its value in the diagnosis of pneumonia in the emergency department with superiority over chest X-ray.

However, there is little data on the thoracic ultrasound semiology of viral pneumonia in general and of COVID in particular.

Peng reported data from 20 patients and compared them to chest CT. The abnormalities are a thickening of the pleuropneumonia line, an interstitial syndrome with B lines, corresponding to frosted glass opacities, confluent B lines (snowstorm appearance) corresponding to interstitial infiltrate, sub-pleural alveolar opacities corresponding to sub-pleural condensations, more frank alveolar images corresponding to alveolar opacities. A multifocal aspect was associated with involvement of more than 2 lobes. However, the frequency of these abnormalities as well as the sensitivity of the echo are not detailed in this article.

Another Italian article describes a clinical case of COVID-19 pneumonia with sub-pleural involvement and irregularity of the pleuro-pulmonary line.

Clinical thoracic ultrasound has a major potential interest during the COVID epidemic: available at the patient's bedside, avoiding the need to move around, feasible for the physician during his visit, easy to clean especially if ultraportable devices are used, fast and not exposing the staff any more than the usual clinical examination.

In order to determine whether this technique is useful in the management of infected patients or patients suspected of COVID-19 infection with respiratory signs, we propose a descriptive prospective study evaluating the ultrasound semiology of COVID-19 pneumonia and the interest of ultrasound in the evolutionary follow-up of these patients.

Conditions

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Pneumonia, Viral COVID-19

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patient hospitalised with COVID-19 infection

Patients admitted to hospital with proven COVID-19 infection with respiratory signs warranting a chest CT scan

No special intervention

Intervention Type OTHER

No special intervention : Ultrasound data will be collected

Interventions

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No special intervention

No special intervention : Ultrasound data will be collected

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients admitted to hospital with proven COVID-19 infection with respiratory signs warranting a chest CT scan

Exclusion Criteria

* Patient not agreeing to have his or her data collected for the study
* Unconscious patient
Minimum Eligible Age

18 Years

Maximum Eligible Age

105 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Intercommunal Creteil

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU Amiens

Amiens, , France

Site Status

CH de la Côte Basque

Bayonne, , France

Site Status

CHU Ambroise Paré

Boulogne-Billancourt, , France

Site Status

CHU Caen

Caen, , France

Site Status

CHG de Chambery

Chambéry, , France

Site Status

Centre Hospitalier Intercommunal de Créteil

Créteil, , France

Site Status

CHU de Limoges

Limoges, , France

Site Status

APHM - Hopital Nord

Marseille, , France

Site Status

CHU de Nancy

Nancy, , France

Site Status

CHU Nîmes

Nîmes, , France

Site Status

CHR Orléans

Orléans, , France

Site Status

CHU Cochin

Paris, , France

Site Status

CHU Poitiers

Poitiers, , France

Site Status

CHU Rouen

Rouen, , France

Site Status

CH Saint-Quentin

Saint-Quentin, , France

Site Status

CHU Larrey - Toulouse

Toulouse, , France

Site Status

CHU de Tours

Tours, , France

Site Status

Countries

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France

Other Identifiers

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COVID-ECHO

Identifier Type: -

Identifier Source: org_study_id

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