Cardio-circulatory and Respiratory Monitoring for Prediction of Outcome in Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients
NCT ID: NCT07109206
Last Updated: 2025-08-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
104 participants
OBSERVATIONAL
2025-08-30
2028-07-20
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Success
Cases with successful weaning and extubation from mechanical ventilation
No interventions assigned to this group
Failed
Group with failed weaning trial
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
2. Patients with pneumothorax, pleural, or pericardial effusion.
3. Patients with injuries, burns, or wounds which precludes the proper application of the device electrodes.
18 Years
ALL
No
Sponsors
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Assiut University
OTHER
Responsible Party
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Karim Osama Mohammed Sleem
Dr
Principal Investigators
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Karim Sleem, Master's Degree
Role: PRINCIPAL_INVESTIGATOR
Assiut University Medical School
Locations
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Assiut University Medical School.
Asyut, Egypt, Egypt
Countries
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Central Contacts
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Facility Contacts
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References
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Hajian-Tilaki K. Receiver Operating Characteristic (ROC) Curve Analysis for Medical Diagnostic Test Evaluation. Caspian J Intern Med. 2013 Spring;4(2):627-35.
McHugh ML. The chi-square test of independence. Biochem Med (Zagreb). 2013;23(2):143-9. doi: 10.11613/bm.2013.018.
Paulus WJ. H2FPEF Score: At Last, a Properly Validated Diagnostic Algorithm for Heart Failure With Preserved Ejection Fraction. Circulation. 2018 Aug 28;138(9):871-873. doi: 10.1161/CIRCULATIONAHA.118.035711. No abstract available.
Pfeffer MA, Shah AM, Borlaug BA. Heart Failure With Preserved Ejection Fraction In Perspective. Circ Res. 2019 May 24;124(11):1598-1617. doi: 10.1161/CIRCRESAHA.119.313572.
Papadimitriou L, Georgiopoulou VV, Kort S, Butler J, Kalogeropoulos AP. Echocardiography in Acute Heart Failure: Current Perspectives. J Card Fail. 2016 Jan;22(1):82-94. doi: 10.1016/j.cardfail.2015.08.001. Epub 2015 Aug 13.
Fathy S, Hasanin AM, Raafat M, Mostafa MMA, Fetouh AM, Elsayed M, Badr EM, Kamal HM, Fouad AZ. Thoracic fluid content: a novel parameter for predicting failed weaning from mechanical ventilation. J Intensive Care. 2020 Mar 5;8:20. doi: 10.1186/s40560-020-00439-2. eCollection 2020.
Vahedian-Azimi A, Gohari-Moghadam K, Rahimi-Bashar F, Samim A, Khoshfetrat M, Mohammadi SM, de Souza LC, Mahmoodpoor A. New integrated weaning indices from mechanical ventilation: A derivation-validation observational multicenter study. Front Med (Lausanne). 2022 Jul 22;9:830974. doi: 10.3389/fmed.2022.830974. eCollection 2022.
Schmidt GA, Girard TD, Kress JP, Morris PE, Ouellette DR, Alhazzani W, Burns SM, Epstein SK, Esteban A, Fan E, Ferrer M, Fraser GL, Gong MN, Hough CL, Mehta S, Nanchal R, Patel S, Pawlik AJ, Schweickert WD, Sessler CN, Strom T, Wilson KC, Truwit JD. Liberation From Mechanical Ventilation in Critically Ill Adults: Executive Summary of an Official American College of Chest Physicians/American Thoracic Society Clinical Practice Guideline. Chest. 2017 Jan;151(1):160-165. doi: 10.1016/j.chest.2016.10.037. Epub 2016 Nov 3.
Sungono V, Hariyanto H, Soesilo TEB, Adisasmita AC, Syarif S, Lukito AA, Widysanto A, Puspitasari V, Tampubolon OE, Sutrisna B, Sudaryo MK. Cohort study of the APACHE II score and mortality for different types of intensive care unit patients. Postgrad Med J. 2022 Dec 1;98(1166):914-918. doi: 10.1136/postgradmedj-2021-140376.
Abdelgawad TA, Ibrahim HM, Elsayed EM, Abdelhamid NS, Bawady SAH, Rezk AR. Hemodynamic monitoring during weaning from mechanical ventilation in critically ill pediatric patients: a prospective observational study. BMC Pediatr. 2024 Oct 26;24(1):681. doi: 10.1186/s12887-024-05110-5.
Faul F, Erdfelder E, Lang AG, Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods. 2007 May;39(2):175-91. doi: 10.3758/bf03193146.
Zakarias D, Marics G, Kovacs K, Jermendy A, Vatai B, Schuster G, Toth-Heyn P, Szabo J A, Lodi C. [Clinical application of the electric cardiometry based non-invasive ICON(R) hemodynamic monitor]. Orv Hetil. 2018 Nov;159(44):1775-1781. doi: 10.1556/650.2018.31225. Hungarian.
Greiwe G, Saad R, Hapfelmeier A, Neumann N, Tariparast P, Saugel B, Flick M. Electrical cardiometry for non-invasive cardiac output monitoring: a method comparison study in patients after coronary artery bypass graft surgery. J Clin Monit Comput. 2025 Apr;39(2):371-376. doi: 10.1007/s10877-024-01246-y. Epub 2024 Dec 11.
Nemer SN, Barbas CS, Caldeira JB, Carias TC, Santos RG, Almeida LC, Azeredo LM, Noe RA, Guimaraes BS, Souza PC. A new integrative weaning index of discontinuation from mechanical ventilation. Crit Care. 2009;13(5):R152. doi: 10.1186/cc8051. Epub 2009 Sep 22.
Agusti A, Vogelmeier C, Faner R. COPD 2020: changes and challenges. Am J Physiol Lung Cell Mol Physiol. 2020 Nov 1;319(5):L879-L883. doi: 10.1152/ajplung.00429.2020. Epub 2020 Sep 23. No abstract available.
Huo Y, Guo S, Zhang K, Zhang T, Li B, Zhang Q, Han Y, Wang X, Hu Z. A clinical study on the ability of the integrative weaning index to predict weaning from mechanical ventilation. Ann Palliat Med. 2020 Sep;9(5):3162-3169. doi: 10.21037/apm-20-1335.
Gadre SK, Duggal A, Mireles-Cabodevila E, Krishnan S, Wang XF, Zell K, Guzman J. Acute respiratory failure requiring mechanical ventilation in severe chronic obstructive pulmonary disease (COPD). Medicine (Baltimore). 2018 Apr;97(17):e0487. doi: 10.1097/MD.0000000000010487.
Other Identifiers
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KarimPhD1
Identifier Type: -
Identifier Source: org_study_id
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