Concussion Recovery and Support Program

NCT ID: NCT07097792

Last Updated: 2025-11-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-10-13

Study Completion Date

2026-07-31

Brief Summary

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Pilot randomized controlled trial (RCT) comparing a novel intervention Concussion Recovery and Support Program (CRISP) for adolescents and young adults (AYA) 18-29 yo with concussion/ mild TBI.

Detailed Description

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The authors are conducting a pilot study to examine the feasibility, acceptability and pilot efficacy of a novel intervention called CRISP for young adults with persistent concussion/ mTBI. CRISP is an adaptation of an evidence-based treatment for chronic pain called Emotional Awareness and Expression Therapy (EAET). EAET targets underlying emotional responses that appear to drive persistent symptoms, and has been found effective for treating headache and other types of pain in randomized controlled trials with moderately strong effect sizes (0.4-0.5).

Individuals who participate in this study will complete 6 sessions of CRISP with a trained therapist over zoom (each 60 minutes) and will also fill out surveys at multiple time points (baseline, 5 weeks, 10 weeks).

Aim 1: Evaluate feasibility and acceptability of CRISP with a pilot study of n=40 individuals with concussion ages 18-30 years who are struggling with headache. Hypothesis: CRISP will be a feasible and acceptable approach to treating AYA with concussion.

Aim 2: Collect pilot data regarding efficacy of CRISP for reducing concussion symptoms and improving function (particularly regarding headache). Hypothesis: Pilot data may show benefit from this approach for improving recovery, though we do not expect significance given the sample size.

Conditions

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Brain Concussion Mild Traumatic Brain Injury Headache

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized Controlled Trial
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors
Data analyst will be blinded

Study Groups

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CRISP

CRISP is an adaptation of an approach called EAET that was originally designed to treat individuals with chronic pain. The goal of this approach is to target underlying emotional reactions that may be causing symptoms to persist. This intervention will be delivered in 6 sessions over 10 weeks.

Group Type EXPERIMENTAL

CRISP (Concussion Recovery and Support Program)

Intervention Type BEHAVIORAL

Mental health intervention targeting suppressed emotion with a goal of facilitating recovery.

Treatment as usual (TAU)

Treatment as usual.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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CRISP (Concussion Recovery and Support Program)

Mental health intervention targeting suppressed emotion with a goal of facilitating recovery.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Diagnosed with a concussion and at least 2 weeks from injury but less than two years.
* New or worsening headache since concussion
* Had at least one day with headache last week of moderate severity or two days with headache of any severity

Exclusion Criteria

* Non-English speaking
* Chronic medical illness/ medical complexity
* Housing instability
* Acute mental health issues such as active suicidality, psychiatric hospitalization within the past 6 months, ER visit for suicidality in the past 6 months or experiencing psychosis or delusions
Minimum Eligible Age

18 Years

Maximum Eligible Age

29 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Seattle Children's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Sara PD Chrisman, MD MPH

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Seattle Children's Research Institute

Seattle, Washington, United States

Site Status RECRUITING

University of Washington

Seattle, Washington, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Sara PD Chrisman, MD MPH

Role: CONTACT

206-884-1490

Allina Flaat, MPH

Role: CONTACT

Facility Contacts

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Sara P Chrisman, MD MPH

Role: primary

206-884-1490

Bethany Pester, PhD

Role: primary

206-884-1490

References

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Lumley MA, Schubiner H. Emotional Awareness and Expression Therapy for Chronic Pain: Rationale, Principles and Techniques, Evidence, and Critical Review. Curr Rheumatol Rep. 2019 May 23;21(7):30. doi: 10.1007/s11926-019-0829-6.

Reference Type BACKGROUND
PMID: 31123837 (View on PubMed)

Other Identifiers

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00005446

Identifier Type: -

Identifier Source: org_study_id

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