Impact of Integrating Two Nano Based Irrigants With Two Activation Techniques in Treatment of Teeth With Acute Pulpitis on Postoperative Pain and Flare up Incidence
NCT ID: NCT07084194
Last Updated: 2025-07-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
64 participants
INTERVENTIONAL
2025-09-10
2026-08-10
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
OTHER
SINGLE
Study Groups
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GROUP I
treated with nanochitosan and passive ultrasonic activation
Chitosan Nanoparticles Irrigant
using Chitosan Nanoparticles irrigant as a final irrigation solution.
ultrasonic activator
activation of nanoparticles irrigants using ultrasonic activator
GROUP II
treated with nanochitosan and laser activation
Chitosan Nanoparticles Irrigant
using Chitosan Nanoparticles irrigant as a final irrigation solution.
Diode Laser Activation
activation of nanoparticles irrigants using diode laser
GROUP III
treated with nano-Aloe Vera and passive ultrasonic activation
aloe vera nanoparticles irrigant
using Aloe Vera Nanoparticles irrigant as a final irrigation solution.
ultrasonic activator
activation of nanoparticles irrigants using ultrasonic activator
GROUP IV
treated with nano-Aloe Vera and laser activation
aloe vera nanoparticles irrigant
using Aloe Vera Nanoparticles irrigant as a final irrigation solution.
Diode Laser Activation
activation of nanoparticles irrigants using diode laser
Interventions
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Chitosan Nanoparticles Irrigant
using Chitosan Nanoparticles irrigant as a final irrigation solution.
aloe vera nanoparticles irrigant
using Aloe Vera Nanoparticles irrigant as a final irrigation solution.
Diode Laser Activation
activation of nanoparticles irrigants using diode laser
ultrasonic activator
activation of nanoparticles irrigants using ultrasonic activator
Eligibility Criteria
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Inclusion Criteria
* multiple-rooted with multiple root canal.
* Permanent teeth with mature apex and complete root formation.
* Without root caries.
* Tooth must be restorable.
* Without anatomical abnormalities such as fusion.
* Healthy patient category I according to ASA.
* Vital tooth, with acute irreversible pulpitis and without peri-apical periodontitis.
* No periapical radiolucency.
* Consent Patients for who consent to participate and attend follow-up appointments.
Exclusion Criteria
* Root canal calcifications.
* Root resorption or fracture.
* Previously root canal treated teeth.
* immunocompromised patients.
* Pregnant females
* Patients with systemic diseases as diabetic or hypertension patients.
* Patients with facial swelling.
* patients who use analgesics or antibiotics within 48-72 hours.
* Allergy to any materials used (e.g., irrigants or anesthetics).
* psychiatric illness
* Teeth that are not indicated for endodontic treatment: bad oral hygiene, mobile teeth, or recessed teeth.
* Previously endodontically treated teeth.
* Teeth with sinus tract.
ALL
Yes
Sponsors
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Minia University
OTHER
Responsible Party
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Rabee Ibrahaim Ismail Alhabibi
Rabee Alhabibi
Central Contacts
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Other Identifiers
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EC Reaseach NO.1079
Identifier Type: -
Identifier Source: org_study_id
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