Brain-computer Interface With Plantar Pneumoorthoses for Post-stroke Rehabilitation

NCT ID: NCT07081308

Last Updated: 2025-07-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-10-05

Study Completion Date

2026-12-31

Brief Summary

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STUDY PURPOSE The investigators are testing a new rehabilitation system that helps stroke patients recover their ability to walk and think more clearly. This system, called brain-computer interface with plantar pneumorthoses, uses brain signals to control a special device that provides gentle pressure to the feet, similar to what you feel when walking. The goal is to help patients regain walking skills, improve memory and thinking, and feel better emotionally.

STUDY QUESTIONS

The main questions the study aims to answer are:

Whether the investigated technology can improve walking in post-stroke patients? Whether the training to control the technology can improve cognitive function in post-stroke patients?

HOW THE STUDY WORKS The investigators compare two groups - one using the new system, another group receiving standard rehabilitation therapy.

Up to 15 patients will try the new system: 10 sessions, each lasting 12 minutes (about 2 weeks, Monday-Friday).

WHAT HAPPENS DURING TREATMENT?

The equipment includes:

Brain monitoring device: Safe infrared light sensors placed on the patient's head (like a cap) Computer software: Reads brain signals when the patient thinks about walking Foot device: Special pneumatic shoes that provide gentle pressure to the patient's feet Screen: Shows visual feedback during training.

What the patient will do:

Sit comfortably in a chair with special shoes on their feet, Complete the task: imagine walking or relax when instructed, What the patient will experience: They will see colors change on the screen and feel gentle pressure on their feet.

Detailed Description

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INTERVENTION NIRS-BCI-Korvit System Components: NIRScout hardware-software complex (16 light sources, 8 detectors); Software for brain activity classification; Korvit pneumoorthesis for plantar support load reproduction; 22-inch monitor for task demonstration Training Procedure: Patient seated with lower limbs fixed in pneumatic orthoses; Task: kinesthetically imagine walking or relax; Feedback: visual (color change on screen) and tactile (support load through orthosis).

Training structure: 16 blocks alternating walking imagination and relaxation/ ASSESSMENT

Motor Function:

* Fugl-Meyer Scale for Lower Extremity (maximum 34 points, clinically significant improvement ≥6 points);
* 10-meter Walk Test (clinically significant improvement ≥0.16 m/s);
* Timed Up and Go Test (clinically significant improvement ≥3 seconds).

Cognitive Functions and Emotional State:

* Addenbrooke's Cognitive Examination III (ACE III);
* Hospital Anxiety and Depression Scale (HADS). EXPECTED OUTCOMES.

The study aims to confirm the effectiveness of NIRS-BCI combined with plantar support load simulator for:

* Gait restoration;
* Cognitive function improvement;
* Emotional state normalization in post-stroke patients SAFETY The procedure is safe and poses no health risks. Possible minor fatigue after sessions. The study can be discontinued at any stage upon patient request or if adverse effects occur.

INNOVATION This research represents a novel approach combining non-invasive brain-computer interface technology with proprioceptive feedback systems for comprehensive post-stroke rehabilitation, addressing both motor and cognitive recovery simultaneously

Conditions

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Stroke

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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BCI

Stroke patients receiving NIRS-BCI-pneumoorthesis training in combination with standard therapy

Group Type EXPERIMENTAL

NIRS-BCI-pneumoorthesis

Intervention Type DEVICE

Patients recieve 10 NIRS-BCI-pneumoorthesis trainings of 16 minutes each over 2 weeks.

NIRS-BCI-pneumoorthesis Components: NIRScout hardware-software complex (16 light sources, 8 detectors); Software for brain activity classification; Korvit system for plantar support load reproduction; 22-inch monitor for task demonstration.

Training Procedure: Patient seated with lower limbs fixed in pneumatic orthoses; Task: kinesthetically imagine walking or relax; Feedback: visual (color change on screen) and tactile (support load through orthosis).

Training structure: 16 blocks alternating walking imagination and relaxation

Control

Stroke patients receiving standard therapy

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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NIRS-BCI-pneumoorthesis

Patients recieve 10 NIRS-BCI-pneumoorthesis trainings of 16 minutes each over 2 weeks.

NIRS-BCI-pneumoorthesis Components: NIRScout hardware-software complex (16 light sources, 8 detectors); Software for brain activity classification; Korvit system for plantar support load reproduction; 22-inch monitor for task demonstration.

Training Procedure: Patient seated with lower limbs fixed in pneumatic orthoses; Task: kinesthetically imagine walking or relax; Feedback: visual (color change on screen) and tactile (support load through orthosis).

Training structure: 16 blocks alternating walking imagination and relaxation

Intervention Type DEVICE

Other Intervention Names

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neurobiofeedback

Eligibility Criteria

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Inclusion Criteria

* Age 18-80 years
* Primary or recurrent supratentorial ischemic stroke
* Stroke onset 7 days to 24 months
* Moderate to mild post-stroke lower limb motor impairments
* Clinical stability
* Voluntary participation and signing of informed consent

Exclusion Criteria

* Severe cognitive impairments preventing instruction compliance
* Sensory or severe motor aphasia
* Severe visual impairments
* Lower limb contractures
* Inability to maintain sitting position
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Pirogov Russian National Research Medical University

OTHER

Sponsor Role collaborator

Institute of Higher Nervous Activity and Neurophysiology of RAS

UNKNOWN

Sponsor Role collaborator

Research Center of Neurology, Russia

OTHER_GOV

Sponsor Role lead

Responsible Party

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Natalia Suponeva

Director of Institute

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Russian center of Neurology and Neurosciences

Moscow, , Russia

Site Status RECRUITING

Countries

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Russia

Central Contacts

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Roman Kh Lyukmanov, PhD

Role: CONTACT

+74953747776

Olesya Al Mokienko, PhD

Role: CONTACT

+74953747776

Facility Contacts

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Roman Kh Lyukmanov, PhD

Role: primary

4953747776

Olesya Al Mokienko, PhD

Role: backup

+74953747776

Other Identifiers

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NIRS-BCI-Korvit

Identifier Type: -

Identifier Source: org_study_id

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