Effect of Regular Physical Activity in Normal-Weight Individuals With Type 2 Diabetes and Abdominal Obesity

NCT ID: NCT07071545

Last Updated: 2025-07-17

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 249247 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2010-01-01
• Study Completion Date: 2023-09-30

Brief Summary

Individuals with T2DM accompanied by abdominal obesity tend to experience worse clinical outcomes. To identify modifiable factors that may improve these outcomes, the investigators conducted a retrospective cohort study using data from the Korean National Health Insurance Service (K-NHIS) database to evaluate the impact of regular physical activity.

Detailed Description

It is well established that patients with T2DM and abdominal obesity have worse clinical outcomes. This holds true even among individuals with a normal body weight but central (abdominal) obesity. In this study, the investigators aimed to determine whether engaging in regular physical activity (defined as vigorous exercise at least three times per week) is associated with improved clinical outcomes in normal-weight individuals with abdominal obesity. Specifically, we compared the incidence of MACCE between normal-weight patients with type 2 diabetes who had abdominal obesity and those who did not.

Conditions

Diabetes (DM); Physical Activity

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Study Groups

Abdominal obesity

Individuals were classified as having abdominal obesity.

Regular physical activity

Intervention Type: BEHAVIORAL

Moderate-to-vigorous physical activity at least three times per week.

No regular physical activity

Intervention Type: BEHAVIORAL

The group that did not engage in physical activity according to the guidelines

Without abdominal obesity

Individuals were classified as not having abdominal obesity.

No interventions assigned to this group

Interventions

Regular physical activity

Moderate-to-vigorous physical activity at least three times per week.

Intervention Type: BEHAVIORAL

No regular physical activity

The group that did not engage in physical activity according to the guidelines

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Patients who were newly diagnosed with T2DM and had a normal body weight at the time of diagnosis.

Exclusion Criteria

• Patients with any pre-existing diabetes-related complications
• Patients who were overweight or obese based on BMI criteria

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Samsung Medical Center

OTHER

Sponsor Role: lead

Responsible Party

Ki Hong Choi

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

DM_abdominalobesity

Identifier Type: -

Identifier Source: org_study_id